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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
14221
World Ranking
8740
National Ranking
115

Overview

Janne Lehtiö is affiliated with the Karolinska Institute in Sweden and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research covers a broad range of subfields including molecular biology, oncology, cancer research, immunology, and genetics.

The scientist's work addresses various main topics such as cancer genomics and diagnostics, bioinformatics and genomic networks, RNA modifications and cancer, acute myeloid leukemia research, immunotherapy and immune responses, ubiquitin and proteasome pathways, and chronic lymphocytic leukemia research.

Janne Lehtiö has published in several well-known scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • eLife
  • Blood
  • Cancer Research

Recent papers authored or co-authored by Lehtiö include:

  • DEqMS: A Method for Accurate Variance Estimation in Differential Protein Expression Analysis, 2020, Molecular & Cellular Proteomics
  • The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology, 2022, Nature Cancer
  • Subcellular proteomics, 2021, Nature Reviews Methods Primers
  • Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms, 2021, Nature Cancer
  • Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal, 2020, Nature Medicine

Lehtiö's frequent co-authors include:

  • Mattias Vesterlund
  • Georgios Mermelekas
  • Lukas M. Orre
  • Henrik J. Johansson
  • Rozbeh Jafari

Their research contributions span over 114 publications in biochemistry, genetics, and molecular biology and 87 in medicine, indicating a multidisciplinary approach within the biomedical sciences. The work also involves significant exploration into molecular techniques that support precision oncology and clinical decision-making systems.

Best Publications

  • Cells release subpopulations of exosomes with distinct molecular and biological properties

    Eduard Willms;Henrik J. Johansson;Imre Mäger;Imre Mäger;Yi Lee

  • Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

    Joel Z. Nordin;Yi Lee;Pieter Vader;Imre Mäger;Imre Mäger

  • Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-kappaB signaling

    Johnathon D. Anderson;Henrik J. Johansson;Calvin S. Graham;Mattias Vesterlund

  • Significantly higher levels of vascular endothelial growth factor (VEGF) and shorter survival times for patients with primary operable triple-negative breast cancer

    B.K. Linderholm;H. Hellborg;U. Johansson;G. Elmberger

  • The binding specificity and affinity determinants of family 1 and family 3 cellulose binding modules

    Janne Lehtiö;Junji Sugiyama;Malin Gustavsson;Linda Fransson

  • Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.

    Samir E L Andaloussi;Taavi Lehto;Imre Mäger;Katri Rosenthal-Aizman

  • HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics

    Rui M M Branca;Lukas M Orre;Henrik J Johansson;Viktor Granholm

  • RIFINs are adhesins implicated in severe Plasmodium falciparum malaria

    Suchi Goel;Mia Palmkvist;Kirsten Moll;Nicolas Joannin

  • MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

    Hanna Zirath;Anna Frenzel;Ganna Oliynyk;Lova Segerström

  • Multiple Ionization Mass Spectrometry Strategy Used To Reveal the Complexity of Metabolomics

    Anders Nordström;Elizabeth Want;Trent Northen;Janne Lehtiö

  • Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach.

    Erika Bereczki;Rui M. Branca;Paul T. Francis;Joana B. Pereira

  • The viral protein corona directs viral pathogenesis and amyloid aggregation

    Kariem Ezzat;Kariem Ezzat;Maria Pernemalm;Sandra Pålsson;Thomas C. Roberts;Thomas C. Roberts

  • SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization.

    Lukas Minus Orre;Mattias Vesterlund;Yanbo Pan;Taner Arslan

  • Breast cancer quantitative proteome and proteogenomic landscape

    Henrik J Johansson;Fabio Socciarelli;Nathaniel M Vacanti;Nathaniel M Vacanti;Mads H Haugen

  • Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles

    Jinghuan Li;Yi Lee;Henrik J. Johansson;Imre Mäger

  • In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

    Oscar E. Simonson;Dimitrios Mougiakakos;Nina Heldring;Giulio Bassi

  • DEqMS: A Method for Accurate Variance Estimation in Differential Protein Expression Analysis.

    Yafeng Zhu;Lukas M. Orre;Yan Zhou Tran;Georgios Mermelekas

  • Multi-omic data analysis using Galaxy

    Jorrit Boekel;John M Chilton;Ira R Cooke;Peter L Horvatovich

  • Stable linker peptides for a cellulose-binding domain–lipase fusion protein expressed in Pichia pastoris

    Malin Gustavsson;Janne Lehtiö;Stuart Denman;Tuula T. Teeri

  • Tumour suppressor p16INK4a – anoikis‐favouring decrease in N/O‐glycan/cell surface sialylation by down‐regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model

    Maho Amano;Hanna Eriksson;Joachim C. Manning;Katharina M. Detjen

Frequent Co-Authors

Samir El Andaloussi
Samir El Andaloussi Karolinska Institute
Per-Johan Jakobsson
Per-Johan Jakobsson Karolinska University Hospital
Matthew J.A. Wood
Matthew J.A. Wood University of Oxford
Catharina Larsson
Catharina Larsson Karolinska University Hospital
Thomas Helleday
Thomas Helleday Karolinska Institute
Peter Nilsson
Peter Nilsson Royal Institute of Technology
Tuula T. Teeri
Tuula T. Teeri Royal Swedish Academy of Engineering Sciences
Johan Hansson
Johan Hansson Karolinska Institute
Elzbieta Glaser
Elzbieta Glaser Stockholm University
Annika Scheynius
Annika Scheynius Karolinska Institute

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