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D-Index
87
Citations
30964
World Ranking
13561
National Ranking
255

Overview

Johan Hansson is a researcher affiliated with the Karolinska Institute in Sweden. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, focusing on oncology and molecular biology within these broader domains.

Their work addresses several specialized subfields, including Oncology, Molecular Biology, Immunology, Genetics, and Dermatology. The main topics covered in their research include Cutaneous Melanoma Detection and Management, Melanoma and MAPK Pathways, PI3K/AKT/mTOR signaling in cancer, Genetic Associations and Epidemiology, Mast cells and histamine, Immune Cells in Cancer, and Cancer Immunotherapy and Biomarkers.

Johan Hansson has contributed to a number of scientific publications, featured in various journals and venues such as Nature Genetics, Scientific Reports, Cancer Immunology Immunotherapy, BMC Public Health, and bioRxiv (Cold Spring Harbor Laboratory). Key recent papers include:

  • Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility (2020, Nature Genetics)
  • PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma (2021, Scientific Reports)
  • High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma (2020, Cancer Immunology Immunotherapy)
  • Birth cohort-specific trends of sun-related behaviors among individuals from an international consortium of melanoma-prone families (2021, BMC Public Health)
  • PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma (2020, bioRxiv - Cold Spring Harbor Laboratory)

Collaboration is a significant aspect of their work, as evidenced by frequent co-authors such as Christian Ingvar, Håkan Olsson, D. Timothy Bishop, Paola Ghiorzo, and Esther Azizi. Each of these collaborators has contributed to multiple publications alongside Johan Hansson.

Best Publications

  • Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

    G.V. Long;D. Stroyakovskiy;H. Gogas;E. Levchenko

  • Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

    Georgina V. Long;Georgina V. Long;Daniil Stroyakovskiy;Helen Gogas;Evgeny Levchenko

  • Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

    Thorunn Rafnar;Patrick Sulem;Simon N Stacey;Frank Geller

  • Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.

    G. V. Long;K. T. Flaherty;D. Stroyakovskiy;H. Gogas

  • Geographical Variation in the Penetrance of CDKN2A Mutations for Melanoma

    D. Timothy Bishop;Florence Demenais;Alisa M. Goldstein;Wilma Bergman

  • A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma

    Omid Hamid;Henrik Schmidt;Aviram Nissan;Laura Ridolfi

  • FBXW7/hCDC4 is a general tumor suppressor in human cancer

    Shahab Akhoondi;Dahui Sun;Natalie von der Lehr;Sophia Apostolidou

  • Genome-wide association study identifies three loci associated with melanoma risk.

    D Timothy Bishop;Florence Demenais;Mark M Iles;Mark Harland

  • Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity.

    Koji Kono;Flavio Salazar-Onfray;Max Petersson;Johan Hansson

  • NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.

    Katarina Omholt;Anton Platz;Lena Kanter;Ulrik Ringborg

  • Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma‐prone families from three continents

    Alisa M Goldstein;May Chan;Mark Harland;Nicholas K Hayward

  • Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign

    Isabel Poschke;Dimitrios Mougiakakos;Johan Hansson;Giuseppe V. Masucci

  • High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL

    Alisa M. Goldstein;May Chan;Mark Harland;Elizabeth M. Gillanders

  • A Prospective Study of Pigmentation, Sun Exposure, and Risk of Cutaneous Malignant Melanoma in Women

    Marit Bragelien Veierød;Elisabete Weiderpass;Magnus Thörn;Johan Hansson

  • Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

    Elisa A Rozeman;Alexander M Menzies;Alexander C J van Akkooi;Chandra Adhikari

  • Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expression.

    M Matsuda;F Salazar;M Petersson;G Masucci

  • ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma.

    Daniel F Gudbjartsson;Patrick Sulem;Simon N Stacey;Alisa M Goldstein

  • New common variants affecting susceptibility to basal cell carcinoma

    Simon N Stacey;Patrick Sulem;Gisli Masson;Sigurjon A Gudjonsson

  • NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing

    Esther Edlundh-Rose;Suzanne Egyházi;Katarina Omholt;Eva Månsson-Brahme

  • Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas.

    Keiran S.M. Smalley;Mercedes Lioni;Maurizia Dalla Palma;Min Xiao

Frequent Co-Authors

Håkan Olsson
Håkan Olsson Lund University
Susana Puig
Susana Puig University of Barcelona
Giuseppe Masucci
Giuseppe Masucci Karolinska Institute
Nelleke A. Gruis
Nelleke A. Gruis Leiden University Medical Center
Rolf Kiessling
Rolf Kiessling Karolinska Institute
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute
Florence Demenais
Florence Demenais Université Paris Cité
Graham J. Mann
Graham J. Mann Australian National University
Alisa M. Goldstein
Alisa M. Goldstein National Institutes of Health
D. Timothy Bishop
D. Timothy Bishop University of Leeds

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