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Overview

Jinru Shia is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on medicine, with a significant emphasis on oncology, pathology and forensic medicine, surgery, pulmonary and respiratory medicine, and cancer research.

The scientist has concentrated on several main topics throughout their work, including:

  • Genetic factors in colorectal cancer
  • Colorectal cancer surgical treatments
  • Colorectal cancer treatments and studies
  • Colorectal and anal carcinomas
  • Cancer genomics and diagnostics
  • Gastric cancer management and outcomes
  • Colorectal cancer screening and detection

Several of their recent papers include:

  • PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer, 2022, New England Journal of Medicine
  • Mismatch Repair-Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy, 2020, Clinical Cancer Research
  • L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer, 2020, Nature Cancer
  • A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers, 2021, JNCI Journal of the National Cancer Institute
  • Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer, 2022, Nature Medicine

Jinru Shia frequently publishes in the following venues:

  • Journal of Clinical Oncology
  • Laboratory Investigation
  • Modern Pathology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JCO Precision Oncology

Their work involves collaboration with multiple researchers, with frequent co-authors including:

  • Julio García-Aguilar
  • Martin R. Weiser
  • Andrea Cercek
  • Zsofia K. Stadler
  • Rona Yaeger

Best Publications

  • Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors That Do Not Express the Epidermal Growth Factor Receptor by Immunohistochemistry

    Ki Young Chung;Jinru Shia;Nancy E. Kemeny;Manish Shah

  • Immunotherapy in colorectal cancer: rationale, challenges and potential.

    Karuna Ganesh;Zsofia K. Stadler;Andrea Cercek;Robin B. Mendelsohn

  • Immunohistochemistry versus Microsatellite Instability Testing For Screening Colorectal Cancer Patients at Risk For Hereditary Nonpolyposis Colorectal Cancer Syndrome: Part I. The Utility of Immunohistochemistry

    Jinru Shia

  • Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer

    Rona Yaeger;Walid K. Chatila;Marla D. Lipsyc;Jaclyn F. Hechtman

  • Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

    Wassim Abida;Michael L. Cheng;Joshua Armenia;Sumit Middha

  • Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer

    Alicia Latham;Preethi Srinivasan;Yelena Kemel;Jinru Shia

  • Operative blood loss independently predicts recurrence and survival after resection of hepatocellular carcinoma.

    Steven C Katz;Jinru Shia;Kui Hin Liau;Mithat Gonen

  • Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.

    Andrea Cercek;Campbell S.D. Roxburgh;Campbell S.D. Roxburgh;Paul Strombom;J. Joshua Smith

  • Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Bryony A Thompson;Bryony A Thompson;Amanda B Spurdle;John-Paul Plazzer;Marc S Greenblatt

  • Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer.

    Jose G. Guillem;David B. Chessin;Alfred M. Cohen;Jinru Shia

  • Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies

    James J Harding;Subhiksha Nandakumar;Joshua Armenia;Danny N Khalil

  • Neoadjuvant Chemotherapy Without Routine Use of Radiation Therapy for Patients With Locally Advanced Rectal Cancer: A Pilot Trial

    Deborah Schrag;Martin R. Weiser;Karyn A. Goodman;Mithat Gon̈en

  • Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy

    J. Joshua Smith;Paul Strombom;Oliver S. Chow;Campbell S. Roxburgh;Campbell S. Roxburgh

  • Long-term survival following treatment of pseudomyxoma peritonei: an analysis of surgical therapy

    Thomas J. Miner;Jinru Shia;David P. Jaques;David S. Klimstra

  • Neuroendocrine carcinomas of the colon and rectum.

    P. E. Bernick;D. S. Klimstra;J. Shia;B. Minsky

  • A rectal cancer organoid platform to study individual responses to chemoradiation.

    Karuna Ganesh;Chao Wu;Kevin P. O’Rourke;Bryan C. Szeglin

  • Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

    A Rose Brannon;Efsevia Vakiani;Brooke E Sylvester;Sasinya N Scott

  • Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix.

    Laura H Tang;Jinru Shia;Robert A Soslow;Deepti Dhall

  • Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data.

    Sumit Middha;Liying Zhang;Khedoudja Nafa;Gowtham Jayakumaran

  • Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations

    Zishuo I. Hu;Jinru Shia;Jinru Shia;Zsofia K. Stadler;Zsofia K. Stadler;Anna M. Varghese;Anna M. Varghese

Frequent Co-Authors

Martin R. Weiser
Martin R. Weiser Memorial Sloan Kettering Cancer Center
Philip B. Paty
Philip B. Paty Memorial Sloan Kettering Cancer Center
David S. Klimstra
David S. Klimstra Yale University
Jose G. Guillem
Jose G. Guillem University of North Carolina at Chapel Hill
Leonard Saltz
Leonard Saltz Memorial Sloan Kettering Cancer Center
Mithat Gonen
Mithat Gonen Memorial Sloan Kettering Cancer Center
William R. Jarnagin
William R. Jarnagin Memorial Sloan Kettering Cancer Center
Michael F. Berger
Michael F. Berger Memorial Sloan Kettering Cancer Center
Michael I. D’Angelica
Michael I. D’Angelica Memorial Sloan Kettering Cancer Center
Julio Garcia-Aguilar
Julio Garcia-Aguilar Memorial Sloan Kettering Cancer Center

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