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Kutty Selva Nandakumar

Kutty Selva Nandakumar

D-Index & Metrics

Immunology

D-Index
49
Citations
8821
World Ranking
4344
National Ranking
98

Overview

Kutty Selva Nandakumar is affiliated with the Karolinska Institute in Sweden, with a research focus primarily on medicine, immunology, and microbiology. Their academic output has extensively covered immunology and related subfields such as rheumatology, molecular biology, infectious diseases, and immunology and allergy.

The scientist's major research topics include rheumatoid arthritis research and therapies, systemic lupus erythematosus research, psoriasis treatment and pathogenesis, NF-κB signaling pathways, cell adhesion molecules research, dermatology and skin diseases, and immune cell function and interaction.

Frequent coauthors contributing to their publications include Rikard Holmdahl, Kui Cheng, Huimei Wu, Jiaxin Ou, and Yanpeng Li. Their work is commonly published in venues such as Frontiers in Immunology, Vaccines, Journal of Inflammation Research, Journal of Medicinal Chemistry, and International Immunopharmacology.

Notable recent papers authored or co-authored by Nandakumar include:

  • Recent Research on Flavonoids and their Biomedical Applications, 2020, Current Medicinal Chemistry
  • Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis, 2020, Mediators of Inflammation
  • 'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models, 2021, Annals of the Rheumatic Diseases
  • Optimization of CAR-T Cell-Based Therapies Using Small-Molecule-Based Safety Switches, 2021, Journal of Medicinal Chemistry
  • Kaempferol modulates IFN-γ induced JAK-STAT signaling pathway and ameliorates imiquimod-induced psoriasis-like skin lesions, 2022, International Immunopharmacology

Kutty Selva Nandakumar has contributed to book publications, including a title published by Frontiers Media: Systemic Lupus Erythematosus - Predisposition Factors, Pathogenesis, Diagnosis, Treatment and Disease Models (2023).

Best Publications

  • Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.

    Kutty Selva Nandakumar;Lars Svensson;Rikard Holmdahl

  • Inhibiting the C5–C5a receptor axis

    Trent M. Woodruff;Kutty S. Nandakumar;Francesco Tedesco

  • Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease.

    René Pfeifle;Tobias Rothe;Natacha Ipseiz;Hans U Scherer

  • Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

    Hüseyin Uysal;Robert Bockermann;Kutty S. Nandakumar;Kutty S. Nandakumar;Bettina Sehnert

  • Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

    Gustaf Wigerblad;Duygu B. Bas;Cátia Fernades-Cerqueira;Akilan Krishnamurthy

  • In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012.

    Anders Kielland;Thomas Blom;Kutty Selva Nandakumar;Rikard Holmdahl

  • Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

    Kutty Selva Nandakumar;Rikard Holmdahl

  • Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

    Kutty Selva Nandakumar;Johan Bäcklund;Mikael Vestberg;Rikard Holmdahl

  • Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse.

    Harald Burkhardt;Tobias Koller;Åke Engström;Kutty Selva Nandakumar

  • Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcγRIIB

    Kutty Selva Nandakumar;Maria Andrén;Pernilla Martinsson;Estelle Bajtner

  • Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice

    Ia Khmaladze;Tiina Kelkka;Simon Guerard;Kajsa Wing

  • Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

    Max Albert Hietala;Kutty S Nandakumar;Linda Persson;Susann Fahlén

  • ‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models

    Silvia Hayer;Margriet J Vervoordeldonk;Maria C Denis;Marietta Armaka

  • Ethanol prevents development of destructive arthritis

    Ing-Marie Jonsson;Margareta Verdrengh;Mikael Brisslert;Sofia Lindblad

  • Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.

    Kutty Selva Nandakumar;Rikard Holmdahl

  • Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.

    Duygu B. Bas;Jie Su;Katalin Sandor;Nilesh M. Agalave

  • IL-10-deficient B10.Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with anti-type II collagen antibodies

    Åsa C. M. Johansson;Ann-Sofie Hansson;Kutty S. Nandakumar;Johan Bäcklund

  • Blocking of experimental arthritis by cleavage of IgG antibodies in vivo

    Kutty Selva Nandakumar;Björn P Johansson;Lars Björck;Rikard Holmdahl

  • Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases.

    Akhilesh Kumar Shakya;Kutty Selva Nandakumar

  • Antibodies to citrullinated proteins: molecular interactions and arthritogenicity.

    Hüseyin Uysal;Kutty Selva Nandakumar;Christoph Kessel;Sabrina Haag

  • Collagen antibody induced arthritis

    Kutty Selva Nandakumar;Rikard Holmdahl

Frequent Co-Authors

Rikard Holmdahl
Rikard Holmdahl Karolinska Institute
Lars Björck
Lars Björck Lund University
Ashok Kumar
Ashok Kumar Indian Institute of Technology Kanpur
Camilla I. Svensson
Camilla I. Svensson Karolinska Institute
Vivianne Malmström
Vivianne Malmström Karolinska University Hospital
Donald McNaughton
Donald McNaughton Monash University
Per-Johan Jakobsson
Per-Johan Jakobsson Karolinska University Hospital
Anca I. Catrina
Anca I. Catrina Karolinska University Hospital
Trent M. Woodruff
Trent M. Woodruff University of Queensland
Lars Klareskog
Lars Klareskog Karolinska Institute

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