John D. Lambris focuses on Complement system, Immunology, Innate immune system, Immune system and Complement. His Complement system research is multidisciplinary, relying on both Biochemistry and Cell biology. Immunology is frequently linked to Neuroscience in his study.
His biological study spans a wide range of topics, including Cell, Crosstalk, Immunity, Transplantation and Effector. His work in Complement addresses subjects such as Drug discovery, which are connected to disciplines such as Eculizumab. He combines subjects such as Complement inhibitor and TLR2 with his study of Complement receptor.
John D. Lambris mainly investigates Complement system, Immunology, Complement, Biochemistry and Cell biology. Complement system is closely attributed to Molecular biology in his study. His Molecular biology study incorporates themes from Receptor, Peptide sequence and Epitope, Antibody, Monoclonal antibody.
Immunology is a component of his Inflammation, Immune system, Innate immune system, C5a receptor and Sepsis studies. Many of his studies on Cell biology involve topics that are commonly interrelated, such as Anaphylatoxin. His Alternative complement pathway research incorporates elements of Complement factor B and Factor H.
Complement system, Immunology, Inflammation, Complement and Immune system are his primary areas of study. His Complement system study integrates concerns from other disciplines, such as Receptor and Cell biology. In Immunology, John D. Lambris works on issues like Disease, which are connected to Bioinformatics.
His work carried out in the field of Inflammation brings together such families of science as C5a receptor, Complement C5a and Cancer research. His studies in Complement integrate themes in fields like Neuroscience, Drug discovery and Intensive care medicine. His work in Alternative complement pathway addresses issues such as Classical complement pathway, which are connected to fields such as Complement receptor.
John D. Lambris spends much of his time researching Complement system, Immunology, Innate immune system, Immune system and Complement. John D. Lambris interconnects Regulator, Drug discovery and Cell biology in the investigation of issues within Complement system. As a member of one scientific family, he mostly works in the field of Immunology, focusing on Disease and, on occasion, Transplantation and Crosstalk.
His research integrates issues of Sepsis, Anaphylatoxin, Signal transduction, Polytrauma and Effector in his study of Innate immune system. The various areas that John D. Lambris examines in his Complement study include Targeted therapy, Clinical trial, Neuroscience and Intensive care medicine. He has researched Alternative complement pathway in several fields, including Classical complement pathway and Glomerulopathy.
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Complement: a key system for immune surveillance and homeostasis
Daniel Ricklin;George Hajishengallis;Kun Yang;John D Lambris.
Nature Immunology (2010)
The classical complement cascade mediates CNS synapse elimination.
Beth Stevens;Nicola J. Allen;Luis E. Vazquez;Gareth R. Howell.
Cell (2007)
Generation of C5a in the absence of C3: a new complement activation pathway.
Markus Huber-Lang;J Vidya Sarma;Firas S Zetoune;Daniel Rittirsch.
Nature Medicine (2006)
Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement
George Hajishengallis;Shuang Liang;Mark A. Payne;Ahmed Hashim.
Cell Host & Microbe (2011)
Complement evasion by human pathogens
John D. Lambris;Daniel Ricklin;Brian V. Geisbrecht.
Nature Reviews Microbiology (2008)
Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
Guillermina Girardi;Jessica Berman;Patricia Redecha;Lynn Spruce.
Journal of Clinical Investigation (2003)
Modulation of the antitumor immune response by complement
Maciej M Markiewski;Robert A DeAngelis;Fabian Benencia;Fabian Benencia;Salome K Ricklin-Lichtsteiner.
Nature Immunology (2008)
Drusen complement components C3a and C5a promote choroidal neovascularization
Miho Nozaki;Brian J. Raisler;Eiji Sakurai;J. Vidya Sarma.
Proceedings of the National Academy of Sciences of the United States of America (2006)
The Role of Complement in Inflammatory Diseases From Behind the Scenes into the Spotlight
Maciej M. Markiewski;John D. Lambris.
American Journal of Pathology (2007)
Molecular Intercommunication between the Complement and Coagulation Systems
Umme Amara;Michael A. Flierl;Daniel Rittirsch;Andreas Klos.
Journal of Immunology (2010)
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