D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 105 Citations 38,974 316 World Ranking 222 National Ranking 149

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

John D. Lambris focuses on Complement system, Immunology, Innate immune system, Immune system and Complement. His Complement system research is multidisciplinary, relying on both Biochemistry and Cell biology. Immunology is frequently linked to Neuroscience in his study.

His biological study spans a wide range of topics, including Cell, Crosstalk, Immunity, Transplantation and Effector. His work in Complement addresses subjects such as Drug discovery, which are connected to disciplines such as Eculizumab. He combines subjects such as Complement inhibitor and TLR2 with his study of Complement receptor.

His most cited work include:

  • Complement: a key system for immune surveillance and homeostasis (2210 citations)
  • The classical complement cascade mediates CNS synapse elimination. (1764 citations)
  • Generation of C5a in the absence of C3: a new complement activation pathway. (744 citations)

What are the main themes of his work throughout his whole career to date?

John D. Lambris mainly investigates Complement system, Immunology, Complement, Biochemistry and Cell biology. Complement system is closely attributed to Molecular biology in his study. His Molecular biology study incorporates themes from Receptor, Peptide sequence and Epitope, Antibody, Monoclonal antibody.

Immunology is a component of his Inflammation, Immune system, Innate immune system, C5a receptor and Sepsis studies. Many of his studies on Cell biology involve topics that are commonly interrelated, such as Anaphylatoxin. His Alternative complement pathway research incorporates elements of Complement factor B and Factor H.

He most often published in these fields:

  • Complement system (44.00%)
  • Immunology (34.21%)
  • Complement (18.48%)

What were the highlights of his more recent work (between 2014-2021)?

  • Complement system (44.00%)
  • Immunology (34.21%)
  • Inflammation (12.14%)

In recent papers he was focusing on the following fields of study:

Complement system, Immunology, Inflammation, Complement and Immune system are his primary areas of study. His Complement system study integrates concerns from other disciplines, such as Receptor and Cell biology. In Immunology, John D. Lambris works on issues like Disease, which are connected to Bioinformatics.

His work carried out in the field of Inflammation brings together such families of science as C5a receptor, Complement C5a and Cancer research. His studies in Complement integrate themes in fields like Neuroscience, Drug discovery and Intensive care medicine. His work in Alternative complement pathway addresses issues such as Classical complement pathway, which are connected to fields such as Complement receptor.

Between 2014 and 2021, his most popular works were:

  • Complement in disease: a defence system turning offensive (240 citations)
  • Complement as a target in COVID-19? (233 citations)
  • PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer (208 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

John D. Lambris spends much of his time researching Complement system, Immunology, Innate immune system, Immune system and Complement. John D. Lambris interconnects Regulator, Drug discovery and Cell biology in the investigation of issues within Complement system. As a member of one scientific family, he mostly works in the field of Immunology, focusing on Disease and, on occasion, Transplantation and Crosstalk.

His research integrates issues of Sepsis, Anaphylatoxin, Signal transduction, Polytrauma and Effector in his study of Innate immune system. The various areas that John D. Lambris examines in his Complement study include Targeted therapy, Clinical trial, Neuroscience and Intensive care medicine. He has researched Alternative complement pathway in several fields, including Classical complement pathway and Glomerulopathy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Complement: a key system for immune surveillance and homeostasis

Daniel Ricklin;George Hajishengallis;Kun Yang;John D Lambris.
Nature Immunology (2010)

2947 Citations

The classical complement cascade mediates CNS synapse elimination.

Beth Stevens;Nicola J. Allen;Luis E. Vazquez;Gareth R. Howell.
Cell (2007)

2218 Citations

Generation of C5a in the absence of C3: a new complement activation pathway.

Markus Huber-Lang;J Vidya Sarma;Firas S Zetoune;Daniel Rittirsch.
Nature Medicine (2006)

1000 Citations

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

George Hajishengallis;Shuang Liang;Mark A. Payne;Ahmed Hashim.
Cell Host & Microbe (2011)

861 Citations

Complement evasion by human pathogens

John D. Lambris;Daniel Ricklin;Brian V. Geisbrecht.
Nature Reviews Microbiology (2008)

749 Citations

Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

Guillermina Girardi;Jessica Berman;Patricia Redecha;Lynn Spruce.
Journal of Clinical Investigation (2003)

720 Citations

Drusen complement components C3a and C5a promote choroidal neovascularization

Miho Nozaki;Brian J. Raisler;Eiji Sakurai;J. Vidya Sarma.
Proceedings of the National Academy of Sciences of the United States of America (2006)

673 Citations

The Role of Complement in Inflammatory Diseases From Behind the Scenes into the Spotlight

Maciej M. Markiewski;John D. Lambris.
American Journal of Pathology (2007)

619 Citations

Modulation of the antitumor immune response by complement

Maciej M Markiewski;Robert A DeAngelis;Fabian Benencia;Fabian Benencia;Salome K Ricklin-Lichtsteiner.
Nature Immunology (2008)

612 Citations

Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

Arvind Sahu;John D. Lambris.
Immunological Reviews (2001)

589 Citations

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