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Microbiology

D-Index
94
Citations
27903
World Ranking
577
National Ranking
266

Overview

Gary H. Cohen is a researcher affiliated with the University of Pennsylvania in the United States. Their work primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these fields, Cohen's focus includes subfields such as Epidemiology, Immunology, Genetics, Virology, and Molecular Biology.

The main topics of Cohen's research involve Herpesvirus Infections and Treatments, Cytomegalovirus and herpesvirus research, Virus-based gene therapy research, Poxvirus research and outbreaks, Toxin Mechanisms and Immunotoxins, Animal Virus Infections Studies, and Immunotherapy and Immune Responses.

Gary H. Cohen has published extensively in various scientific venues. The most frequent publication outlets include:

  • Viruses
  • Journal of Virology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • PLoS Pathogens

Their recent publications illustrate a focus on viral vaccine development and molecular interactions related to herpes simplex virus (HSV). Selected recent papers include:

  • "An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection" (2020, PLoS Pathogens)
  • "Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine" (2020, Vaccine)
  • "Localization of the Interaction Site of Herpes Simplex Virus Glycoprotein D (gD) on the Membrane Fusion Regulator, gH/gL" (2020, Journal of Virology)
  • "A Trivalent HSV-2 gC2, gD2, gE2 Nucleoside-Modified mRNA-LNP Vaccine Provides Outstanding Protection in Mice against Genital and Non-Genital HSV-1 Infection, Comparable to the Same Antigens Derived from HSV-1" (2023, Viruses)
  • "Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies" (2020, Molecular Therapy - Methods & Clinical Development)

Gary H. Cohen frequently collaborates with several other researchers. Notable frequent co-authors include:

  • Tina M. Cairns
  • Harvey M. Friedman
  • Doina Atanasiu
  • Sita Awasthi
  • Lauren M. Hook

Best Publications

  • A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry

    Deepak Shukla;Jian Liu;Peter Blaiklock;Nicholas W. Shworak;Nicholas W. Shworak

  • Entry of Alphaherpesviruses Mediated by Poliovirus Receptor-Related Protein 1 and Poliovirus Receptor

    Robert J. Geraghty;Claude Krummenacher;Claude Krummenacher;Gary H. Cohen;Gary H. Cohen;Roselyn J. Eisenberg;Roselyn J. Eisenberg

  • LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

    Davide N Mauri;Reinhard Ebner;Rebecca I Montgomery;Kristine D Kochel

  • A Cell Surface Protein with Herpesvirus Entry Activity (HveB) Confers Susceptibility to Infection by Mutants of Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, and Pseudorabies Virus

    Morgyn S. Warner;Robert J. Geraghty;Wanda M. Martinez;Rebecca I. Montgomery

  • Crystal structure of glycoprotein B from herpes simplex virus 1.

    Ekaterina E. Heldwein;Huan Lou;Florent C. Bender;Gary H. Cohen

  • Three classes of cell surface receptors for alphaherpesvirus entry.

    Patricia G. Spear;Roselyn J. Eisenberg;Gary H. Cohen

  • Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

    Patricia L. Earl;Jeffrey L. Americo;Linda S. Wyatt;Leigh Anne Eller

  • Herpes simplex virus glycoprotein D bound to the human receptor HveA.

    Andrea Carfı́;Sharon H. Willis;J.Charles Whitbeck;Claude Krummenacher

  • Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells.

    Harvey M. Friedman;Gary H. Cohen;Roselyn J. Eisenberg;Cynthia A. Seidel

  • Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry

    J C Whitbeck;C Peng;H Lou;R Xu

  • Herpes virus fusion and entry: a story with many characters.

    Roselyn J. Eisenberg;Doina Atanasiu;Tina M. Cairns;John R. Gallagher

  • Structure of Unliganded Hsv Gd Reveals a Mechanism for Receptor-Mediated Activation of Virus Entry.

    Claude Krummenacher;Vinit M Supekar;J Charles Whitbeck;Eric Lazear

  • Protective Immunity to Vaccinia Virus Induced by Vaccination with Multiple Recombinant Outer Membrane Proteins of Intracellular and Extracellular Virions

    Christiana Fogg;Shlomo Lustig;J. Charles Whitbeck;Roselyn J. Eisenberg

  • Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL

    Tirumala K Chowdary;Tina M Cairns;Doina Atanasiu;Gary H Cohen

  • Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

    Doina Atanasiu;Wan Ting Saw;Gary H. Cohen;Roselyn J. Eisenberg

  • Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry

    Claude Krummenacher;Anthony V. Nicola;Anthony V. Nicola;J. Charles Whitbeck;Huan Lou

  • The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

    Isabelle A. Rooney;Kris D. Butrovich;Alison A. Glass;Stephen Borboroglu

  • Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C.

    R J Frink;R Eisenberg;G Cohen;E K Wagner

  • Glycoprotein D Receptor-Dependent, Low-pH-Independent Endocytic Entry of Herpes Simplex Virus Type 1

    Richard S. B. Milne;Anthony V. Nicola;J. Charles Whitbeck;Roselyn J. Eisenberg

  • Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion.

    Doina Atanasiu;J. Charles Whitbeck;Tina M. Cairns;Brigid Reilly

Frequent Co-Authors

Roselyn J. Eisenberg
Roselyn J. Eisenberg University of Pennsylvania
J. Charles Whitbeck
J. Charles Whitbeck Integral Molecular (United States)
Harvey M. Friedman
Harvey M. Friedman University of Pennsylvania
Patricia G. Spear
Patricia G. Spear Northwestern University
John D. Lambris
John D. Lambris University of Pennsylvania
Andrea Carfi
Andrea Carfi Novartis (Switzerland)
Bernard Moss
Bernard Moss National Institutes of Health
Don C. Wiley
Don C. Wiley Harvard University
Joseph C. Glorioso
Joseph C. Glorioso University of Pittsburgh
William R. Abrams
William R. Abrams New York University

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