World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
91
Citations
26190
World Ranking
662
National Ranking
308

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Roselyn J. Eisenberg was affiliated with the University of Pennsylvania in the United States. Their research primarily focused on virology and immunology, with significant contributions to the understanding of herpesvirus infections and related mechanisms.

Their scholarly work explored several main fields of study, including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Subfields that featured prominently in their work were Epidemiology, Immunology, Virology, Genetics, and Cell Biology. Key topics covered in their research involved Herpesvirus Infections and Treatments, Toxin Mechanisms and Immunotoxins, Poxvirus research and outbreaks, Virus-based gene therapy research, Cytomegalovirus and herpesvirus research, and Proteoglycans and glycosaminoglycans research.

Roselyn J. Eisenberg authored multiple research papers. Notable publications include:

  • Localization of the Interaction Site of Herpes Simplex Virus Glycoprotein D (gD) on the Membrane Fusion Regulator, gH/gL (2020, Journal of Virology)
  • Using Split Luciferase Assay and Anti-Herpes Simplex Virus Glycoprotein Monoclonal Antibodies To Predict a Functional Binding Site between gD and gH/gL (2021, Journal of Virology)
  • Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion (2023, Viruses)
  • Characterization of a Heparan Sulfate Octasaccharide That Binds to Herpes Simplex Virus Type 1 Glycoprotein D (2021, UNC Libraries)

The frequent publication venues for their work included:

  • Journal of Virology
  • Viruses
  • UNC Libraries

Collaborations were an important aspect of their research, with frequent coauthors including Gary H. Cohen, Tina M. Cairns, Doina Atanasiu, Wan Ting Saw, and Huan Lou.

In recognition of their contributions to science, Roselyn J. Eisenberg was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry

    Deepak Shukla;Jian Liu;Peter Blaiklock;Nicholas W. Shworak;Nicholas W. Shworak

  • Entry of Alphaherpesviruses Mediated by Poliovirus Receptor-Related Protein 1 and Poliovirus Receptor

    Robert J. Geraghty;Claude Krummenacher;Claude Krummenacher;Gary H. Cohen;Gary H. Cohen;Roselyn J. Eisenberg;Roselyn J. Eisenberg

  • LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

    Davide N Mauri;Reinhard Ebner;Rebecca I Montgomery;Kristine D Kochel

  • A Cell Surface Protein with Herpesvirus Entry Activity (HveB) Confers Susceptibility to Infection by Mutants of Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, and Pseudorabies Virus

    Morgyn S. Warner;Robert J. Geraghty;Wanda M. Martinez;Rebecca I. Montgomery

  • Crystal structure of glycoprotein B from herpes simplex virus 1.

    Ekaterina E. Heldwein;Huan Lou;Florent C. Bender;Gary H. Cohen

  • Three classes of cell surface receptors for alphaherpesvirus entry.

    Patricia G. Spear;Roselyn J. Eisenberg;Gary H. Cohen

  • Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

    Patricia L. Earl;Jeffrey L. Americo;Linda S. Wyatt;Leigh Anne Eller

  • Herpes simplex virus glycoprotein D bound to the human receptor HveA.

    Andrea Carfı́;Sharon H. Willis;J.Charles Whitbeck;Claude Krummenacher

  • Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells.

    Harvey M. Friedman;Gary H. Cohen;Roselyn J. Eisenberg;Cynthia A. Seidel

  • Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry

    J C Whitbeck;C Peng;H Lou;R Xu

  • Herpes virus fusion and entry: a story with many characters.

    Roselyn J. Eisenberg;Doina Atanasiu;Tina M. Cairns;John R. Gallagher

  • Structure of Unliganded Hsv Gd Reveals a Mechanism for Receptor-Mediated Activation of Virus Entry.

    Claude Krummenacher;Vinit M Supekar;J Charles Whitbeck;Eric Lazear

  • Protective Immunity to Vaccinia Virus Induced by Vaccination with Multiple Recombinant Outer Membrane Proteins of Intracellular and Extracellular Virions

    Christiana Fogg;Shlomo Lustig;J. Charles Whitbeck;Roselyn J. Eisenberg

  • Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL

    Tirumala K Chowdary;Tina M Cairns;Doina Atanasiu;Gary H Cohen

  • Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

    Doina Atanasiu;Wan Ting Saw;Gary H. Cohen;Roselyn J. Eisenberg

  • Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry

    Claude Krummenacher;Anthony V. Nicola;Anthony V. Nicola;J. Charles Whitbeck;Huan Lou

  • The Lymphotoxin-β Receptor Is Necessary and Sufficient for LIGHT-mediated Apoptosis of Tumor Cells

    Isabelle A. Rooney;Kris D. Butrovich;Alison A. Glass;Stephen Borboroglu

  • Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C.

    R J Frink;R Eisenberg;G Cohen;E K Wagner

  • Glycoprotein D Receptor-Dependent, Low-pH-Independent Endocytic Entry of Herpes Simplex Virus Type 1

    Richard S. B. Milne;Anthony V. Nicola;J. Charles Whitbeck;Roselyn J. Eisenberg

  • Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion.

    Doina Atanasiu;J. Charles Whitbeck;Tina M. Cairns;Brigid Reilly

Frequent Co-Authors

Gary H. Cohen
Gary H. Cohen University of Pennsylvania
J. Charles Whitbeck
J. Charles Whitbeck Integral Molecular (United States)
Patricia G. Spear
Patricia G. Spear Northwestern University
Harvey M. Friedman
Harvey M. Friedman University of Pennsylvania
Andrea Carfi
Andrea Carfi Novartis (Switzerland)
John D. Lambris
John D. Lambris University of Pennsylvania
Bernard Moss
Bernard Moss National Institutes of Health
Don C. Wiley
Don C. Wiley Harvard University
Carl F. Ware
Carl F. Ware Sanford Burnham Prebys Medical Discovery Institute
Patricia L. Earl
Patricia L. Earl National Institute of Allergy and Infectious Diseases

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