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Immunology
Norway
2026

D-Index & Metrics

Immunology

D-Index
98
Citations
45651
World Ranking
778
National Ranking
5

Medicine

D-Index
99
Citations
46055
World Ranking
8466
National Ranking
33

Research.com Recognitions

  • 2026 - Research.com Immunology in Norway Leader Award
  • 2025 - Research.com Immunology in Norway Leader Award
  • 2022 - Research.com Immunology in Norway Leader Award
  • Member of the Norwegian Academy of Science and Letters Biochemistry, Biophysics, and Molecular Biology
  • Member of the Norwegian Academy of Science and Letters Biochemistry, Biophysics, and Molecular Biology
  • Member of the Norwegian Academy of Science and Letters Biochemistry, Biophysics, and Molecular Biology
  • Member of the Norwegian Academy of Science and Letters Biochemistry, Biophysics, and Molecular Biology

Overview

Terje Espevik is affiliated with the Norwegian University of Science and Technology in Norway. Their research activity focuses on immunology, molecular biology, and medicine, with substantial contributions across the fields of Biochemistry, Genetics, and Molecular Biology.

Espevik's main research areas cover topics such as inflammasomes and immune disorders, the complement system in diseases, immune response and inflammation, interferon and immune responses, atherosclerosis and cardiovascular diseases, NF-κB signaling pathways, and immune cell function and interaction.

Frequent publication venues for Espevik include:

  • The Journal of Immunology (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • Frontiers in Immunology (2 publications)
  • Immunobiology (2 publications)
  • Science Immunology (1 publication)

Some of the recent papers authored or co-authored by Espevik are:

  • "Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation" (2021) published in Science Immunology
  • "Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis" (2020) published in EBioMedicine
  • "Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells" (2022) published in iScience
  • "TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria" (2020) published in Journal of Leukocyte Biology
  • "Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation" (2023) published in Cell Reports Medicine

Espevik frequently collaborates with other researchers, including Liv Ryan, Tom Eirik Mollnes, Maria Yurchenko, Astrid Skjesol, and Nathalie Niyonzima, with whom Espevik has co-authored multiple publications.

Espevik is a member of the Norwegian Academy of Science and Letters in the section of Biochemistry, Biophysics, and Molecular Biology.

Best Publications

  • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

    Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois

  • TLR9 signals after translocating from the ER to CpG DNA in the lysosome

    Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald

  • A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes.

    Terje Espevik;Jon Nissen-Meyer

  • The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

    A Waage;P Brandtzaeg;A Halstensen;P Kierulf

  • Association between tumour necrosis factor in serum and fatal outcome in patients with meningococcal disease.

    A. Waage;A. Halstensen;T. Espevik

  • TOLL-LIKE RECEPTOR 2 FUNCTIONS AS A PATTERN RECOGNITION RECEPTOR FOR DIVERSE BACTERIAL PRODUCTS

    Egil Lien;Egil Lien;Timothy J. Sellati;Atsutoshi Yoshimura;Trude H. Flo

  • The Proinflammatory CD14+CD16+DR++ Monocytes Are a Major Source of TNF

    Kai-Uwe Belge;Farshid Dayyani;Alexia Horelt;Maciej Siedlar

  • Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming

    Anette Christ;Anette Christ;Patrick Günther;Mario A.R. Lauterbach;Peter Duewell

  • Soluble CD14 participates in the response of cells to lipopolysaccharide.

    E A Frey;D S Miller;T G Jahr;A Sundan

  • The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

    Bernardo S Franklin;Lukas Bossaller;Dominic De Nardo;Jacqueline M Ratter

  • A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.

    Desiree van der Kleij;Desiree van der Kleij;Eicke Latz;Jos F.H.M. Brouwers;Yvonne C.M. Kruize

  • Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.

    Pål Aukrust;Thor Ueland;Egil Lien;Klaus Bendtzen

  • Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.

    Eicke Latz;Alberto Visintin;Egil Lien;Egil Lien;Katherine A. Fitzgerald

  • Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

    G E Ranges;I S Figari;T Espevik;M A Palladino

  • Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response.

    A Waage;A Halstensen;R Shalaby;P Brandtzaeg

  • Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity

    Harald Husebye;Øyvind Halaas;Harald Stenmark;Harald Stenmark;Gro Tunheim

  • Inhibition of cytokine production by cyclosporin A and transforming growth factor beta.

    T Espevik;I S Figari;M R Shalaby;G A Lackides

  • Ligand-induced conformational changes allosterically activate Toll-like receptor 9

    Eicke Latz;Anjali Verma;Alberto Visintin;Mei Gong

  • The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

    Øystein Sandanger;Trine Ranheim;Leif Erik Vinge;Leif Erik Vinge;Marte Bliksøen

  • Inflammatory Response After Open Heart Surgery: Release of Heat-Shock Protein 70 and Signaling Through Toll-Like Receptor-4

    Brit Dybdahl;Alexander Wahba;Egil Lien;Trude H. Flo

  • Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (Nature (2010) 464 (1357-1361))

    Peter Duewell;Hajime Kono;Katey J. Rayner;Cherilyn M. Sirois

Frequent Co-Authors

Tom Eirik Mollnes
Tom Eirik Mollnes Oslo University Hospital
Gudmund Skjåk-Bræk
Gudmund Skjåk-Bræk Norwegian University of Science and Technology
Egil Lien
Egil Lien University of Massachusetts Chan Medical School
Anders Sundan
Anders Sundan Norwegian University of Science and Technology
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Pål Aukrust
Pål Aukrust Oslo University Hospital
Stig S. Frøland
Stig S. Frøland University of Oslo
Douglas T. Golenbock
Douglas T. Golenbock University of Massachusetts Chan Medical School
Olav Smidsrød
Olav Smidsrød Norwegian University of Science and Technology
Anders Waage
Anders Waage Norwegian University of Science and Technology

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