World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
82
Citations
22940
World Ranking
939
National Ranking
500

Overview

Paul A. Overbeek is affiliated with Baylor College of Medicine in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable emphasis on cancer research and molecular biology subfields. Additional areas of study include clinical biochemistry and cardiology and cardiovascular medicine.

Their work spans several main topics, including cancer-related molecular mechanisms research, epigenetics and DNA methylation, RNA research and splicing, RNA modifications and cancer, metabolism and genetic disorders, and lipid metabolism and disorders.

Paul A. Overbeek has contributed to multiple publications in a variety of venues. Some of the notable recent papers include:

  • Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1, 2020, Journal of Biological Chemistry
  • PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites, 2021, Cell Reports
  • PGC1α is Required for the Renoprotective Effect of LncRNA Tug1 in vivo and Links Tug1 with Urea Cycle Metabolites, 2021, SSRN Electronic Journal
  • A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development, 2023, Research Square (Research Square)
  • A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development, 2025, Communications Biology

The scientist has collaborated frequently with other researchers, including Jianyin Long, Daniel L. Galvan, Koki Mise, Farhad R. Danesh, and Lin Tan.

Paul A. Overbeek's publications have appeared in various scientific journals and platforms, including:

  • Journal of Biological Chemistry
  • Cell Reports
  • SSRN Electronic Journal
  • Research Square (Research Square)
  • Communications Biology

Best Publications

  • X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.

    Rainer Döffinger;Asma Smahi;Christine Bessia;Frédéric Geissmann

  • Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

    R Agah;P A Frenkel;B A French;L H Michael

  • FVB/N: an inbred mouse strain preferable for transgenic analyses.

    M Taketo;A C Schroeder;L E Mobraaten;K B Gunning

  • CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo

    Robert Passier;Hong Zeng;Norbert Frey;Francisco J. Naya

  • Conserved left–right asymmetry of nodal expression and alterations in murine situs inversus

    Linda A. Lowe;Dorothy M. Supp;Karuna Sampath;Takahiko Yokoyama

  • Reversal of left-right asymmetry : a situs inversus mutation

    Takahiko Yokoyama;Neal G. Copeland;Nancy A. Jenkins;Charles A. Montgomery

  • Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells.

    Wenjian Wang;Yin Wang;Jianyin Long;Jinrong Wang

  • Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia

    Alex W. Monreal;Betsy M. Ferguson;Denis J. Headon;Summer L. Street

  • Involvement of a novel Tnf receptor homologue in hair follicle induction.

    Denis J. Headon;Paul A. Overbeek

  • Gene defect in ectodermal dysplasia implicates a death domain adapter in development.

    Denis J. Headon;Stephanie A. Emmal;Betsy M. Ferguson;Abigail S. Tucker

  • TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice

    Dou Zhang;Vinciane Gaussin;George E. Taffet;Narasimhaswamy S. Belaguli

  • Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy

    Jianyin Long;Shawn S. Badal;Zengchun Ye;Yin Wang

  • A transgenic insertion upstream of Sox9 is associated with dominant XX sex reversal in the mouse

    Colin E. Bishop;Deanne J. Whitworth;Yanjun Qin;Alexander I. Agoulnik

  • Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

    Hidemasa Oh;George E. Taffet;Keith A. Youker;Mark L. Entman

  • Reciprocal requirements for Eda/Edar/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction

    Yuhang Zhang;Philip Tomann;Thomas Andl;Natalie M. Gallant

  • Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse

    David Morgan;Lee Turnpenny;Judith Goodship;Weilie Dai

  • Regulation of mouse lens fiber cell development and differentiation by the Maf gene.

    Brian Z. Ring;Sabine P. Cordes;Paul A. Overbeek;Gregory S. Barsh

  • Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

    Paul A. Overbeek;Ana B. Chepelinsky;Jaspal S. Khillan;Joram Piatigorsky

  • Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice.

    M L Robinson;P A Overbeek;D J Verran;W E Grizzle

  • Mutant Cohesin in Premature Ovarian Failure

    Sandrine Caburet;Valerie A. Arboleda;Elena Llano;Paul A. Overbeek

Frequent Co-Authors

Colin E. Bishop
Colin E. Bishop Wake Forest University
Heiner Westphal
Heiner Westphal National Institutes of Health
Kirill V. Larin
Kirill V. Larin University of Houston
Frank J. Lovicu
Frank J. Lovicu University of Sydney
Eric N. Olson
Eric N. Olson The University of Texas Southwestern Medical Center
Kenneth E. Bernstein
Kenneth E. Bernstein Cedars-Sinai Medical Center
Gerri Hanten
Gerri Hanten Baylor College of Medicine
Richard R. Behringer
Richard R. Behringer The University of Texas MD Anderson Cancer Center
Joram Piatigorsky
Joram Piatigorsky National Institutes of Health
Michael W. Lieberman
Michael W. Lieberman Baylor College of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in Molecular Biology opens many versatile career options, both in research and applied fields. For those looking to apply their scientific foundation in new directions, there are several relevant online degrees and pathways worth considering.

If you are interested in the intersection of science and mental health, an online masters in clinical psychology can leverage your biological knowledge in clinical or research settings. Alternatively, if you are passionate about community work, a human services degree online may offer a quicker route to rewarding roles that support individual and public well-being.

For educators or those wanting to pivot their expertise, making a career change from teacher to speech and language therapist is one pathway that benefits from a scientific background. Similarly, the critical thinking and analytical skills gained from Molecular Biology studies can prepare you for creative industries, such as design and planning, through the best online architecture degree programs.

Exploring these related degrees can help tailor your education and skills to fit evolving industry demands while expanding your impact across diverse professional sectors.

Best Scientists Citing Paul A. Overbeek

Trending Scientists

Recently Published Articles