John W. McAvoy

Overview

Best Publications

• Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration.

  J.W. McAvoy;C.G. Chamberlain

  475
  Citations

• GROWTH FACTOR REGULATION OF LENS DEVELOPMENT

  Frank Lovicu;Johnston McAvoy;Johnston McAvoy

  395
  Citations

• Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition in the Lens: A Model for Cataract Formation

  R.U. de Iongh;E. Wederell;F.J. Lovicu;J.W. McAvoy

  357
  Citations

• Cataract induction in lenses cultured with transforming growth factor-beta

  Angela M. Hales;Coral G. Chamberlain;John W. McAvoy

  267
  Citations

• TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts.

  Angela M. Hales;Mark W. Schulz;Coral G. Chamberlain;John W. McAvoy

  257
  Citations

• Acidic and basic FGF in ocular media and lens: implications for lens polarity and growth patterns

  M.W. Schulz;C.G. Chamberlain;R.U. de Iongh;J.W. McAvoy

  239
  Citations

• Induction of cataract-like changes in rat lens epithelial explants by transforming growth factor beta.

  Jie Liu;Angela M. Hales;Coral G. Chamberlain;John W. McAvoy

  239
  Citations

• FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling.

  Frank J. Lovicu;John W. McAvoy

  237
  Citations

• Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF).

  Coral G. Chamberlain;John W. McAvoy

  217
  Citations

• Growth factors in the eye.

  John W. McAvoy;Coral G. Chamberlain

  181
  Citations

• TGFβ induces morphological and molecular changes similar to human anterior subcapsular cataract

  Frank J Lovicu;Mark W Schulz;Angela M Hales;Lisa N Vincent

  180
  Citations

• Evidence that fibroblast growth factor promotes lens fibre differentiation

  Coral G. Chamberlain;John W. McAvoy

  176
  Citations

• Smad translocation and growth suppression in lens epithelial cells by endogenous TGFbeta2 during wound repair

  Shizuya Saika;Yuka Okada;Takeshi Miyamoto;Yoshitaka Ohnishi

  160
  Citations

• Induction of the Eye Lens

  J.W. McAVOY

  158
  Citations

• A role for Wnt/β-catenin signaling in lens epithelial differentiation

  Richard J.W Stump;Sharyn Ang;Yongjuan Chen;Tatiana von Bahr

  157
  Citations

• Estrogen Protects Lenses against Cataract Induced by Transforming Growth Factor-β (TGFβ)

  Angela M. Hales;Coral G. Chamberlain;Christopher R. Murphy;John W. McAvoy

  154
  Citations

• The role of fibroblast growth factor in eye lens development.

  J. W. McAVOY;C. G. Chamberlain;R. U. De Iongh;N. A. Richardson

  150
  Citations

• Requirement for TGFβ receptor signaling during terminal lens fiber differentiation

  Robbert U. de Iongh;Frank J. Lovicu;Paul A. Overbeek;Michael D. Schneider

  146
  Citations

• TGFβ-Smad signalling in postoperative human lens epithelial cells

  S Saika;T Miyamoto;I Ishida;K Shirai

  143
  Citations

• Understanding the role of growth factors in embryonic development: insights from the lens

  FJ Lovicu;JW McAvoy;RU de Iongh

  128
  Citations