What is she best known for?
The fields of study she is best known for:
Her primary areas of study are Cell biology, Kidney, Kidney development, Internal medicine and Stem cell.
Her Cell biology research includes elements of Cellular differentiation, Induced pluripotent stem cell and Nephron.
Melissa H. Little interconnects Cell type, Transplantation and Directed differentiation in the investigation of issues within Kidney.
Her Kidney development research incorporates elements of Regulation of gene expression and Morphogenesis.
Her Internal medicine research is multidisciplinary, relying on both Endocrinology and Pathology.
The concepts of her Stem cell study are interwoven with issues in Molecular biology and Adult stem cell.
Her most cited work include:
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis (688 citations)
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis (688 citations)
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis (688 citations)
What are the main themes of her work throughout her whole career to date?
Her main research concerns Cell biology, Kidney, Kidney development, Induced pluripotent stem cell and Internal medicine.
Melissa H. Little interconnects Cellular differentiation and Nephron in the investigation of issues within Cell biology.
Bioinformatics is closely connected to Kidney disease in her research, which is encompassed under the umbrella topic of Kidney.
Her Kidney development study also includes
- Regulation of gene expression together with Gene expression profiling,
- Anatomy together with Morphogenesis.
Her work deals with themes such as Reprogramming, Intermediate mesoderm and Organoid, which intersect with Induced pluripotent stem cell.
While the research belongs to areas of Internal medicine, Melissa H. Little spends her time largely on the problem of Endocrinology, intersecting her research to questions surrounding Offspring.
She most often published in these fields:
- Cell biology (53.69%)
- Kidney (32.74%)
- Kidney development (19.76%)
What were the highlights of her more recent work (between 2017-2021)?
- Cell biology (53.69%)
- Induced pluripotent stem cell (23.89%)
- Kidney (32.74%)
In recent papers she was focusing on the following fields of study:
Melissa H. Little mostly deals with Cell biology, Induced pluripotent stem cell, Kidney, Nephron and Kidney development.
Her studies in Cell biology integrate themes in fields like Cell type and Cellular differentiation.
Melissa H. Little has researched Induced pluripotent stem cell in several fields, including Wnt signaling pathway, Reprogramming, Organoid, Kidney morphogenesis and Cell therapy.
Her biological study spans a wide range of topics, including Cell culture, Regenerative medicine, Kidney disease and Directed differentiation.
Her Nephron research focuses on Organogenesis and how it connects with Mesenchyme, Downregulation and upregulation, microRNA, LIN28 and Process.
Melissa H. Little focuses mostly in the field of Kidney development, narrowing it down to topics relating to Internal medicine and, in certain cases, Endocrinology, TSC1, Lesion and PI3K/AKT/mTOR pathway.
Between 2017 and 2021, her most popular works were:
- Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo. (129 citations)
- Evaluation of variability in human kidney organoids. (77 citations)
- Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms (67 citations)
In her most recent research, the most cited papers focused on:
Melissa H. Little focuses on Cell biology, Induced pluripotent stem cell, Organoid, Cellular differentiation and Nephron.
The various areas that Melissa H. Little examines in her Cell biology study include Cell type, Single-cell analysis, Kidney development and Gene expression profiling.
Her Induced pluripotent stem cell research is multidisciplinary, incorporating elements of Reprogramming, Stem cell, Transgene and Cilium.
In her study, Directed differentiation is strongly linked to Kidney, which falls under the umbrella field of Organoid.
Her Cellular differentiation research focuses on Wnt signaling pathway and how it relates to Lineage, Fate mapping and Kidney morphogenesis.
As a member of one scientific family, she mostly works in the field of Nephron, focusing on Kidney metabolism and, on occasion, Organogenesis, microRNA, Downregulation and upregulation, Mesenchyme and LIN28.
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