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Genetics

D-Index
105
Citations
38890
World Ranking
629
National Ranking
94

Research.com Recognitions

  • 2002 - Fellow of the Royal Society, United Kingdom
  • 2001 - Member of Academia Europaea
  • 1993 - Fellow of the Royal Society of Edinburgh

Overview

Nicholas D. Hastie is affiliated with the University of Edinburgh in the United Kingdom. Their research spans several fields within biological and medical sciences, with a focus on genetic and molecular mechanisms related to congenital conditions and physical performance.

The main fields of study covered by their work include Biochemistry, Genetics and Molecular Biology, and Medicine. Within these, subfields emphasized are Molecular Biology, Surgery, Epidemiology, and Genetics.

The primary scientific topics addressed in their research are:

  • Congenital heart defects research
  • Congenital gastrointestinal and neural anomalies
  • Congenital Heart Disease Studies
  • Genetics and Physical Performance
  • Renal and related cancers

Throughout their career, Nicholas D. Hastie has contributed to several publication venues, notably:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Nature Communications

Among their recent published papers are:

  • "Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice," 2021, Scientific Reports
  • "Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability," 2021, Nature Communications
  • "A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape," 2020, UNC Libraries
  • "Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium," 2020, UNC Libraries

Frequent collaborators over various projects have included Thomas P. Wilm, Helen Tanton, Fiona Mutter, Veronica Foisor, and Ben Middlehurst.

Nicholas D. Hastie has been recognized with several honors during their career, including being named a Fellow of the Royal Society of Edinburgh in 1993, a Member of Academia Europaea in 2001, and a Fellow of the Royal Society in the United Kingdom in 2002.

Best Publications

  • Telomere reduction in human colorectal carcinoma and with ageing

    Nicholas D. Hastie;Maureen Dempster;Malcolm G. Dunlop;Alastair M. Thompson

  • Mouse small eye results from mutations in a paired-like homeobox-containing gene.

    Robert E. Hill;Jack Favor;Brigid L. M. Hogan;Carl C. T. Ton

  • Modulation of genetic associations with serum urate levels by body-mass-index in humans

    Jennifer E. Huffman;Eva Albrecht;Alexander Teumer;Massimo Mangino

  • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

    Yurii S Aulchenko;Samuli Ripatti;Ida Lindqvist;Dorret Boomsma

  • GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

    Cornelius A. Rietveld;Sarah E. Medland;Jaime Lane Derringer;Jian Yang

  • The candidate Wilms' tumour gene is involved in genitourinary development

    Kathryn Pritchard-Jones;Stewart Fleming;Duncan Davidson;Wendy Bickmore

  • Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region.

    Carl C. T. Ton;Harri Hirvonen;Hiroshi Miwa;Michael M. Weil

  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

    Anna Köttgen;Anna Köttgen;Eva Albrecht;Alexander Teumer;Veronique Vitart

  • SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

    Veronique Vitart;Igor Rudan;Igor Rudan;Caroline Hayward;Nicola K Gray;Nicola K Gray

  • New loci associated with kidney function and chronic kidney disease

    Anna Köttgen;Anna Köttgen;Cristian Pattaro;Carsten A. Böger;Christian Fuchsberger

  • The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo

    Jane F. Armstrong;Kathryn Pritchard-Jones;Wendy A. Bickmore;Nicholas D. Hastie

  • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Thomas W. Winkler;Anne E. Justice;Mariaelisa Graff;Llilda Barata

  • The human PAX6 gene is mutated in two patients with aniridia.

    Tim Jordan;Isabel Hanson;Dmitri Zaletayev;Shirley Hodgson

  • YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis

    A W Moore;L McInnes;J Kreidberg;N D Hastie

  • High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations

    Maja Pucić;Ana Knezević;Jana Vidic;Barbara Adamczyk

  • Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

    Stefan H Larsson;Jean-Paul Charlieu;Jean-Paul Charlieu;Kiyoshi Miyagawa;Dieter Engelkamp

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Human telomeres contain at least three types of G-rich repeat distributed non-randomly

    Robin C Allshire;Maureen Dempster;Nicholas D. Hastie

  • Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities.

    Andreas Schedl;Allyson Ross;Muriel Lee;Dieter Engelkamp

  • Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

    You-Ying Chau;Roberto Bandiera;Alan Serrels;Ofelia M. Martínez-Estrada

Frequent Co-Authors

Igor Rudan
Igor Rudan University of Edinburgh
Caroline Hayward
Caroline Hayward University of Edinburgh
Harry Campbell
Harry Campbell University of Edinburgh
Veronique Vitart
Veronique Vitart University of Edinburgh
Ozren Polasek
Ozren Polasek University of Split
James F. Wilson
James F. Wilson University of Edinburgh
Alan F. Wright
Alan F. Wright University of Edinburgh
Ivana Kolcic
Ivana Kolcic University of Split
Sarah H. Wild
Sarah H. Wild University of Edinburgh
Jennifer E. Huffman
Jennifer E. Huffman VA Boston Healthcare System

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