World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
73
Citations
32675
World Ranking
2007
National Ranking
915

Overview

Lin Chen is affiliated with the University of Chicago in the United States and conducts research primarily within the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans several subfields including Molecular Biology, Neurology, Oncology, Cellular and Molecular Neuroscience, and Immunology.

The scientist's research topics cover a broad range of areas such as Histone Deacetylase Inhibitors Research, Neuroinflammation and Neurodegeneration Mechanisms, Signaling Pathways in Disease, RNA Research and Splicing, Cancer-related Molecular Pathways, Amyotrophic Lateral Sclerosis Research, and Ubiquitin and Proteasome Pathways.

Frequent publication venues for Lin Chen include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Research Square (Research Square)
  • Nucleic Acids Research
  • Cell Death and Disease

Lin Chen has contributed to several recent scientific papers, including:

  • "Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis," published in 2021 in Nature Communications
  • "A signalling pathway for transcriptional regulation of sleep amount in mice," published in 2022 in Nature
  • "Lipids, apolipoproteins, and prognosis of amyotrophic lateral sclerosis," published in 2020 in Neurology
  • "Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis," published in 2020 in Cell Metabolism
  • "Mechanism of forkhead transcription factors binding to a novel palindromic DNA site," published in 2021 in Nucleic Acids Research

The scientist collaborates frequently with several coauthors, including Yongheng Chen, Yi Kou, Zhuchu Chen, Xiao Lei, and Hudie Wei, reflecting ongoing partnerships in their research endeavors.

Best Publications

  • The GTEx Consortium atlas of genetic regulatory effects across human tissues

    F Aguet;AN Barbeira;R Bonazzola;A Brown

  • Transcriptional regulation by calcium, calcineurin, and NFAT

    Patrick G. Hogan;Lin Chen;Julie Nardone;Anjana Rao

  • FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

    Yongqing Wu;Madhuri Borde;Vigo Heissmeyer;Markus Feuerer

  • The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

    Christine G. Elsik;Christine G. Elsik;Christine G. Elsik;Ross L. Tellam;Kim C. Worley;Kim C. Worley;Richard A. Gibbs

  • Mapping and sequencing of structural variation from eight human genomes

    Jeffrey M. Kidd;Gregory M. Cooper;William F. Donahue;Hillary S. Hayden

  • Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

    Alvaro N. Barbeira;Scott P. Dickinson;Rodrigo Bonazzola;Jiamao Zheng

  • The genome of a songbird

    Wesley C. Warren;David F. Clayton;Hans Ellegren;Arthur P. Arnold

  • Genome analysis of the platypus reveals unique signatures of evolution

    Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney

  • DNA binding site sequence directs glucocorticoid receptor structure and activity.

    Sebastiaan H. Meijsing;Miles A. Pufall;Miles A. Pufall;Alex Y. So;Alex Y. So;Darren L. Bates;Darren L. Bates

  • Comparative and demographic analysis of orang-utan genomes.

    Devin P. Locke;LaDeana W. Hillier;Wesley C. Warren;Kim C. Worley

  • Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.

    David J. Clark;Saravana M. Dhanasekaran;Francesca Petralia;Jianbo Pan

  • Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

    Lin Chen;J. N. Mark Glover;Patrick G. Hogan;Anjana Rao

  • Proteogenomic and metabolomic characterization of human glioblastoma

    Liang-Bo Wang;Alla Karpova;Marina A. Gritsenko;Jennifer E. Kyle

  • Genome architectures revealed by tethered chromosome conformation capture and population-based modeling

    Reza Kalhor;Harianto Tjong;Nimanthi Jayathilaka;Frank Alber

  • The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing

    Karin M. Reinisch;Lin Chen;Gregory L. Verdine;William N. Lipscomb

  • Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.

    Cosma D Dellisanti;Yun Yao;James C Stroud;Zuo-Zhong Wang

  • Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

    Ulrike Peters;Ulrike Peters;Shuo Jiao;Fredrick R. Schumacher;Carolyn M. Hutter;Carolyn M. Hutter

  • Determinants of telomere length across human tissues

    Kathryn Demanelis;Farzana Jasmine;Lin S. Chen;Meytal Chernoff

  • Proteogenomic Characterization of Endometrial Carcinoma.

    Yongchao Dou;Emily A. Kawaler;Daniel Cui Zhou;Marina A. Gritsenko

  • Structure of the DNA-binding domains from NFAT, FOS and JUN bound specifically to DNA

    L. Chen;M. Glover;P. Hogan;A. Rao

Frequent Co-Authors

Evan E. Eichler
Evan E. Eichler University of Washington
Habibul Ahsan
Habibul Ahsan University of Chicago
Gregory L. Verdine
Gregory L. Verdine Harvard University
Eric R. Gamazon
Eric R. Gamazon Vanderbilt University Medical Center
Pei Wang
Pei Wang Icahn School of Medicine at Mount Sinai
Anjana Rao
Anjana Rao La Jolla Institute For Allergy & Immunology
Nancy J. Cox
Nancy J. Cox Vanderbilt University Medical Center
Tina Graves
Tina Graves Washington University in St. Louis
Paul Flicek
Paul Flicek The Jackson Laboratory
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital

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