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Medicine

D-Index
85
Citations
26591
World Ranking
14607
National Ranking
7393

Overview

Benjamin D. Humphreys is affiliated with Washington University in St. Louis in the United States. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with a substantial number of publications also related to Medicine. Within these broad fields, their work focuses on several subfields including Molecular Biology, Nephrology, Pulmonary and Respiratory Medicine, Genetics, and Cancer Research.

The scientist's principal topics of investigation involve Renal and related cancers, Single-cell and spatial transcriptomics, Chronic Kidney Disease and Diabetes, Renal cell carcinoma treatment, Pluripotent Stem Cells Research, Acute Kidney Injury Research, and Renal Transplantation Outcomes and Treatments.

Benjamin D. Humphreys has authored a number of recent papers, several of which have considerable citations. Notable publications include:

  • Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury, 2020, Proceedings of the National Academy of Sciences
  • Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney, 2021, Nature Communications
  • Multi-omics integration in the age of million single-cell data, 2021, Nature Reviews Nephrology
  • Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies, 2022, Cell Metabolism
  • Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis, 2022, Cell Metabolism

The scientist frequently collaborates with colleagues who include Hao Wu, Yoshiharu Muto, Parker C. Wilson, Nicolas Ledru, and Eryn E. Dixon.

Benjamin D. Humphreys has published extensively in several key venues in their research domain. Frequent publication outlets include:

  • Journal of the American Society of Nephrology
  • Kidney International
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Clinical Investigation

Best Publications

  • Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

    Benjamin D. Humphreys;Benjamin D. Humphreys;Shuei Liong Lin;Shuei Liong Lin;Akio Kobayashi;Thomas E. Hudson

  • Intrinsic Epithelial Cells Repair the Kidney after Injury

    Benjamin D. Humphreys;Benjamin D. Humphreys;M. Todd Valerius;Akio Kobayashi;Joshua W. Mugford

  • Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

    Takaharu Ichimura;Edwin J.P.v. Asseldonk;Benjamin D. Humphreys;Lakshman Gunaratnam

  • Mechanisms of Renal Fibrosis.

    Benjamin D Humphreys

  • Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis

    Rafael Kramann;Rafael Kramann;Rebekka K. Schneider;Derek P. DiRocco;Flavia Machado

  • Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis

    Haojia Wu;Yuhei Kirita;Erinn L. Donnelly;Benjamin D. Humphreys

  • Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

    Haojia Wu;Kohei Uchimura;Erinn L. Donnelly;Yuhei Kirita

  • Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis

    Ivica Grgic;Ivica Grgic;Gabriela Campanholle;Vanesa Bijol;Chang Wang

  • Differentiated kidney epithelial cells repair injured proximal tubule

    Tetsuro Kusaba;Matthew Lalli;Rafael Kramann;Rafael Kramann;Rafael Kramann;Akio Kobayashi;Akio Kobayashi

  • Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

    Yuhei Kirita;Yuhei Kirita;Haojia Wu;Kohei Uchimura;Parker C. Wilson

  • Repair of injured proximal tubule does not involve specialized progenitors

    Benjamin D. Humphreys;Suzanne Czerniak;Derek P. DiRocco;Wirasat Hasnain

  • The single-cell transcriptomic landscape of early human diabetic nephropathy

    Parker C. Wilson;Haojia Wu;Yuhei Kirita;Kohei Uchimura

  • Mesenchymal Stem Cells in Acute Kidney Injury

    Benjamin D. Humphreys;Joseph V. Bonventre

  • Mesenchymal Stem Cells in Fibrotic Disease

    Elie El Agha;Elie El Agha;Rafael Kramann;Rebekka K. Schneider;Rebekka K. Schneider;Xiaokun Li

  • Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis

    Benjamin D. Humphreys;Fengfeng Xu;Venkata Sabbisetti;Ivica Grgic

  • Cediranib, an Oral Inhibitor of Vascular Endothelial Growth Factor Receptor Kinases, Is an Active Drug in Recurrent Epithelial Ovarian, Fallopian Tube, and Peritoneal Cancer

    Ursula A. Matulonis;Suzanne Berlin;Percy Ivy;Karin Tyburski

  • Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response.

    Haojia Wu;Andrew F. Malone;Erinn L. Donnelly;Yuhei Kirita

  • Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney.

    Yoshiharu Muto;Parker C. Wilson;Nicolas Ledru;Haojia Wu

  • Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease.

    Rafael Kramann;Rafael Kramann;Claudia Goettsch;Janewit Wongboonsin;Hiroshi Iwata

  • Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney

    Yoshiharu Muto;Parker C. Wilson;Haojia Wu;Sushrut S. Waikar

Frequent Co-Authors

Joseph V. Bonventre
Joseph V. Bonventre Brigham and Women's Hospital
Andrew P. McMahon
Andrew P. McMahon University of Southern California
Sushrut S. Waikar
Sushrut S. Waikar Boston University
Helmut G. Rennke
Helmut G. Rennke Brigham and Women's Hospital
George R. Dubyak
George R. Dubyak Case Western Reserve University
Erik Ingelsson
Erik Ingelsson Stanford University
Johan Ärnlöv
Johan Ärnlöv Karolinska Institute
Steven L. Brody
Steven L. Brody Washington University in St. Louis
Andrew P. Morris
Andrew P. Morris University of Liverpool
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford

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