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Medicine

D-Index
115
Citations
47505
World Ranking
4558
National Ranking
174

Overview

Ton J. Rabelink is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on fields related to medicine and biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology and nephrology.

The main topics of their work include:

  • Renal and related cancers
  • Vasculitis and related conditions
  • Chronic Kidney Disease and Diabetes
  • Systemic Lupus Erythematosus Research
  • Tissue Engineering and Regenerative Medicine
  • Renal Diseases and Glomerulopathies
  • Pluripotent Stem Cells Research

Rabelink has published extensively in several frequent venues, including:

  • Journal of the American Society of Nephrology
  • Nephrology Dialysis Transplantation
  • Kidney International Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Reviews Nephrology

Recent publications demonstrate involvement in studying kidney metabolism, renal cell specialization, and artificial intelligence applications in nephrology. Selected papers include:

  • "Analyzing cell-type-specific dynamics of metabolism in kidney repair" (2022, Nature Metabolism)
  • "Phenotypic diversity and metabolic specialization of renal endothelial cells" (2021, Nature Reviews Nephrology)
  • "Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation" (2022, Cell Stem Cell)
  • "Development and testing of an artificial intelligence tool for predicting end-stage kidney disease in patients with immunoglobulin A nephropathy" (2020, Kidney International)
  • "Oxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell Identity" (2021, Frontiers in Immunology)

They frequently collaborate with a core group of coauthors, including:

  • Y K Onno Teng
  • Bernard M. van den Berg
  • Cees van Kooten
  • Gangqi Wang
  • Cathelijne W. van den Berg

Ton J. Rabelink's subfields of study span molecular biology, nephrology, pulmonary and respiratory medicine, surgery, and rheumatology. Their scholarly output reflects interdisciplinary engagement in these areas related to kidney function, cellular metabolism, and disease mechanisms, supporting ongoing research developments in renal medicine and associated biomedical fields.

Best Publications

  • Endothelial Function and Dysfunction Testing and Clinical Relevance

    John E. Deanfield;Julian P. Halcox;Ton J. Rabelink

  • Olmesartan for the Delay or Prevention of Microalbuminuria in Type 2 Diabetes

    Hermann Haller;Sadayoshi Ito;Joseph L. Izzo;Andrzej Januszewicz

  • Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes

    Cindy J.M. Loomans;Eelco J.P. de Koning;Frank J.T. Staal;Maarten B. Rookmaaker

  • Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

    E Stroes;J Kastelein;F Cosentino;W Erkelens

  • Stent Placement in Patients With Atherosclerotic Renal Artery Stenosis and Impaired Renal Function: A Randomized Trial

    Liesbeth Bax;Arend-Jan J. Woittiez;Hans J. Kouwenberg;Willem P. T. M. Mali

  • Expression of connective tissue growth factor in human renal fibrosis

    Yasuhiko Ito;Jan Aten;Richard J. Bende;Barry S. Oemar

  • Cellular regulation of endothelial nitric oxide synthase.

    Roland Govers;Ton J. Rabelink

  • Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication.

    E.S.G. Stroes;H.A. Koomans;T.J. Rabelink;T.W.A. de Bruin

  • Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

    Anna Rita Cantelmo;Lena Christin Conradi;Aleksandra Brajic;Jermaine Goveia

  • Endothelin-A Receptor Antagonist–Mediated Vasodilatation Is Attenuated by Inhibition of Nitric Oxide Synthesis and by Endothelin-B Receptor Blockade

    Marianne C. Verhaar;Fiona E. Strachan;David E. Newby;Nicholas L. Cruden

  • The relevance of tissue angiotensin-converting enzyme: Manifestations in mechanistic and endpoint data

    Victor J. Dzau;Kenneth Bernstein;David Celermajer;Jerome Cohen;Jerome Cohen

  • Metabolic and Additional Vascular Effects of Thiazolidinediones

    Fabrice M. A. C Martens;Frank L. J. Visseren;Jacinthe Lemay;Eelco J. P. de Koning

  • 5-Methyltetrahydrofolate, the Active Form of Folic Acid, Restores Endothelial Function in Familial Hypercholesterolemia

    M. C. Verhaar;R. M. F. Wever;J. J. P. Kastelein;T. Van Dam

  • Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation.

    Michel L Hijmering;Erik S.G Stroes;Jobien Olijhoek;Barbara A Hutten

  • Atherosclerosis and the two faces of endothelial nitric oxide synthase

    Robert M. F. Wever;Thomas F. Lüscher;Francesco Cosentino;Ton J. Rabelink

  • Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase.

    R. M. F. Wever;T. Van Dam;H. J. M. Van Rijn;F. De Groot

  • Folic acid reverts dysfunction of endothelial nitric oxide synthase

    E. S. G. Stroes;E. E. van Faassen;M. Yo;P. Martasek

  • The Metabolic Syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm

    Jobien K. Olijhoek;Yolanda van der Graaf;Jan-Dirk Banga;Ale Algra

  • Autologous Bone Marrow-Derived Mesenchymal Stromal Cells for the Treatment of Allograft Rejection After Renal Transplantation: Results of a Phase I Study

    Marlies E.J. Reinders;Johan W. de Fijter;Helene Roelofs;Ingeborg M. Bajema

  • Folates and Cardiovascular Disease

    M.C. Verhaar;E. Stroes;T.J. Rabelink

Frequent Co-Authors

Cees van Kooten
Cees van Kooten Leiden University Medical Center
J. Wouter Jukema
J. Wouter Jukema Leiden University Medical Center
Johan van der Vlag
Johan van der Vlag Radboud University
Martin J. Schalij
Martin J. Schalij Leiden University Medical Center
Jeroen J. Bax
Jeroen J. Bax Leiden University Medical Center
Menno V. Huisman
Menno V. Huisman Leiden University Medical Center
Erik S.G. Stroes
Erik S.G. Stroes University of Amsterdam
Friedo W. Dekker
Friedo W. Dekker Leiden University Medical Center
Alberto M. Pereira
Alberto M. Pereira University of Amsterdam

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