George R. Dubyak

Overview

Best Publications

• Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

  G. R. Dubyak;Chakib El-Moatassim

  1584
  Citations

• Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

  Minh Lam;George R Dubyak;Lie Chen;Gabriel Nuñez

  872
  Citations

• Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.

  Michael Scott Simonson;S. Wann;P. Mene;George R Dubyak

  739
  Citations

• Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells

  Michael G. Strainic;Jinbo Liu;Danping Huang;Fengqi An

  682
  Citations

• Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages

  Yan Qu;Luigi Franchi;Gabriel Nunez;George R. Dubyak

  678
  Citations

• Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis

  Joseph K. Rathkey;Junjie Zhao;Zhonghua Liu;Yinghua Chen

  559
  Citations

• The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor.

  G R Dubyak;A Kleinzeller

  504
  Citations

• Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.

  Mausita Karmakar;Michael A. Katsnelson;George R. Dubyak;Eric Pearlman

  471
  Citations

• Towards a revised nomenclature for P1 and P2 receptors

  Bertil B. Fredholm;Maria P. Abbracchio;Geoffrey Burnstock;George R. Dubyak

  468
  Citations

• Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

  J. Michelle Kahlenberg;George R. Dubyak

  447
  Citations

• Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

  Luigi Franchi;Thirumala Devi Kanneganti;George R. Dubyak;Gabriel Núñez

  412
  Citations

• Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

  Yan Qu;Shahram Misaghi;Kim Newton;Laurie L. Gilmour

  407
  Citations

• Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase

  Reza Beigi;Eiry Kobatake;Masuo Aizawa;George R. Dubyak

  373
  Citations

• N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

  Mausita Karmakar;Martin Minns;Elyse N. Greenberg;Jose Diaz-Aponte

  328
  Citations

• K+ Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+ Signaling

  Michael A. Katsnelson;L. Graham Rucker;Hana M. Russo;George R. Dubyak

  305
  Citations

• Intracellular calcium changes trigger connexin 32 hemichannel opening

  Elke De Vuyst;Elke Decrock;Liesbet Cabooter;George R Dubyak

  301
  Citations

• Colocalization of ATP Release Sites and Ecto-ATPase Activity at the Extracellular Surface of Human Astrocytes

  Sheldon M. Joseph;Marisa R. Buchakjian;George R. Dubyak

  280
  Citations

• Signal transduction by P2-purinergic receptors for extracellular ATP.

  George R. Dubyak

  276
  Citations

• Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor.

  Benjamin D. Humphreys;Janet Rice;Sylvia B. Kertesy;George R. Dubyak

  271
  Citations

• Isoquinolines as Antagonists of the P2X7 Nucleotide Receptor: High Selectivity for the Human versus Rat Receptor Homologues

  Benjamin D. Humphreys;Caterina Virginio;Annmarie Surprenant;Janet Rice

  255
  Citations