James S. Wiley

Overview

Best Publications

• Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

  Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  1397
  Citations

• Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

  Melanie Bahlo;David R Booth;Simon A Broadley;Matthew A Brown;Matthew A Brown

  531
  Citations

• Modification of red cell membrane structure by cholesterol-rich lipid dispersions. A model for the primary spur cell defect.

  R A Cooper;E C Arner;J S Wiley;S J Shattil

  479
  Citations

• A GLU (496) TO ALA POLYMORPHISM LEADS TO LOSS OF FUNCTION OF THE HUMAN P2X7 RECEPTOR

  Ben J. Gu;Weiyi Zhang;Rebecca A. Worthington;Ronald Sluyter

  402
  Citations

• A Furosemide-Sensitive Cotransport of Sodium plus Potassium in the Human Red Cell

  James S. Wiley;Richard A. Cooper

  329
  Citations

• Cytosine Arabinoside Influx and Nucleoside Transport Sites in Acute Leukemia

  J. S. Wiley;S. P. Jones;W. H. Sawyer;A. R. P. Paterson

  287
  Citations

• A Polymorphism in the P2X7 Gene Increases Susceptibility to Extrapulmonary Tuberculosis

  Suran L. Fernando;Bernadette M. Saunders;Ronald Sluyter;Kristen K. Skarratt

  279
  Citations

• Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.

  Mia Thorsélius;Alexander Kröber;Fiona Murray;Ulf Thunberg

  274
  Citations

• Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors

  B. J. Gu;W. Y. Zhang;L. J. Bendall;I. P. Chessell

  251
  Citations

• The isoquinoline derivative KN‐62 a potent antagonist of the P2Z‐receptor of human lymphocytes

  Caroline Eve Gargett;James S. Wiley

  248
  Citations

• P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region

  Megan L. Smart;Ben Gu;Rekha G. Panchal;James Wiley

  243
  Citations

• The human P2X7 receptor and its role in innate immunity

  J. S. Wiley;R. Sluyter;R. Sluyter;B. J. Gu;B. J. Gu;L. Stokes

  229
  Citations

• An Ile-568 to Asn Polymorphism Prevents Normal Trafficking and Function of the Human P2X7 Receptor

  James S. Wiley;Lan-Phuong Dao-Ung;Changping Li;Anne N. Shemon

  225
  Citations

• Adenosine Triphosphate–Induced Shedding of CD23 and L-Selectin (CD62L) From Lymphocytes Is Mediated by the Same Receptor but Different Metalloproteases

  B. Gu;L.J. Bendall;J.S. Wiley

  211
  Citations

• A Thr357 to Ser Polymorphism in Homozygous and Compound Heterozygous Subjects Causes Absent or Reduced P2X7 Function and Impairs ATP-induced Mycobacterial Killing by Macrophages

  Anne N. Shemon;Ronald Sluyter;Suran L. Fernando;Alison L. Clarke

  207
  Citations

• Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome

  V. L. Sheen;A. Jansen;M. H. Chen;E. Parrini

  206
  Citations

• Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

  Leanne Stokes;Stephen J. Fuller;Ronald Sluyter;Ronald Sluyter;Kristen K. Skarratt

  203
  Citations

• A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study

  James S Wiley;L Phuong Dao-Ung;Ben J Gu;Ronald Sluyter

  201
  Citations

• An Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor.

  Ben J. Gu;Ronald Sluyter;Kristen K. Skarratt;Anne N. Shemon

  190
  Citations

• Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes.

  Ronald Sluyter;Anne N Shemon;James S Wiley

  188
  Citations