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Medicine

D-Index
88
Citations
45604
World Ranking
12919
National Ranking
6604

Overview

Manish A. Shah is affiliated with Cornell University in the United States and has contributed extensively to research in medicine, with a particular focus on oncology. Their work spans a wide range of subfields including oncology, pulmonary and respiratory medicine, surgery, molecular biology, and pathology and forensic medicine.

The scientist's research primarily centers on cancer treatment and management, with notable emphasis on gastric cancer, esophageal cancer, cancer immunotherapy, colorectal cancer, lung cancer, pancreatic and hepatic oncology, and studies on barrier structure and function.

Frequent coauthors in Manish A. Shah's collaborative network include Peter C. Enzinger, Kohei Shitara, Florian Lordick, Eric Van Cutsem, and Jaffer A. Ajani.

Manish A. Shah's publication record features numerous papers in leading venues, with significant contributions in journals such as:

  • Journal of Clinical Oncology
  • Annals of Oncology
  • Cancer Research
  • Clinical Cancer Research
  • Future Oncology

Their recent papers include:

  • Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study, 2021, The Lancet
  • Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer, 2020, Journal of Clinical Oncology
  • Zolbetuximab plus mFOLFOX6 in patients with CLDN18.2-positive, HER2-negative, untreated, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (SPOTLIGHT): a multicentre, randomised, double-blind, phase 3 trial, 2023, The Lancet
  • Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial, 2023, Nature Medicine
  • Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline, 2020, Journal of Clinical Oncology

The topics addressed in their work include:

  • Gastric Cancer Management and Outcomes
  • Esophageal Cancer Research and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Colorectal Cancer Treatments and Studies
  • Lung Cancer Treatments and Mutations
  • Pancreatic and Hepatic Oncology Research
  • Barrier Structure and Function Studies

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial

    Charles S. Fuchs;Toshihiko Doi;Raymond W. Jang;Raymond W. Jang;Kei Muro

  • Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors That Do Not Express the Epidermal Growth Factor Receptor by Immunohistochemistry

    Ki Young Chung;Jinru Shia;Nancy E. Kemeny;Manish Shah

  • Bevacizumab in Combination With Chemotherapy As First-Line Therapy in Advanced Gastric Cancer: A Randomized, Double-Blind, Placebo-Controlled Phase III Study

    Atsushi Ohtsu;Manish A. Shah;Eric Van Cutsem;Sun Young Rha

  • Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study

    Jong-Mu Sun;Lin Shen;Manish A Shah;Peter Enzinger

  • Targeting the Cell Cycle: A New Approach to Cancer Therapy

    Gary K. Schwartz;Manish A. Shah

  • Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer

    Takashi Kojima;Manish A Shah;Kei Muro;Eric Francois

  • Chemotherapy Use, Performance Status, and Quality of Life at the End of Life

    Holly G. Prigerson;Yuhua Bao;Manish A. Shah;M. Elizabeth Paulk

  • Gastric cancer epidemiology and risk factors.

    Douglas E. Guggenheim;Manish A. Shah

  • Bevacizumab in Combination With Chemotherapy As First-Line Therapy in Advanced Gastric Cancer: A Biomarker Evaluation From the AVAGAST Randomized Phase III Trial

    Eric Van Cutsem;Sanne de Haas;Yoon-Koo Kang;Atsushi Ohtsu

  • Multicenter Phase II Study of Irinotecan, Cisplatin, and Bevacizumab in Patients With Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

    Manish A. Shah;Ramesh K. Ramanathan;David H. Ilson;Alissa Levnor

  • Cell cycle-mediated drug resistance: an emerging concept in cancer therapy.

    Manish A. Shah;Gary K. Schwartz

  • Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study

    Peter C. Thuss-Patience;Manish A. Shah;Atsushi Ohtsu;Eric Van Cutsem

  • Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus: The Phase 2 KEYNOTE-180 Study.

    Manish A. Shah;Takashi Kojima;Daniel Hochhauser;Peter Enzinger

  • Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase 3 study.

    Josep Tabernero;Paulo M. Hoff;Lin Shen;Atsushi Ohtsu

  • Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis

    Y.Y. Janjigian;D. Werner;C. Pauligk;K. Steinmetz

  • Comparison of gastric cancer survival following R0 resection in the United States and Korea using an internationally validated nomogram.

    Vivian E. Strong;Kyo Young Song;Cho Hyun Park;Lindsay M. Jacks

  • Locally Advanced, Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline

    Edward P. Balaban;Pamela B. Mangu;Alok A. Khorana;Manish A. Shah

  • Bevacizumab in Combination With Chemotherapy as First-LineTherapyinAdvancedGastricCancer:ABiomarker EvaluationFromtheAVAGASTRandomizedPhaseIIITrial

    Eric Van Cutsem;Sanne de Haas;Yoon-Koo Kang;Atsushi Ohtsu

Frequent Co-Authors

David P. Kelsen
David P. Kelsen Memorial Sloan Kettering Cancer Center
Laura H. Tang
Laura H. Tang Memorial Sloan Kettering Cancer Center
Daniel G. Coit
Daniel G. Coit Memorial Sloan Kettering Cancer Center
Eileen M. O’Reilly
Eileen M. O’Reilly Memorial Sloan Kettering Cancer Center
Mithat Gonen
Mithat Gonen Memorial Sloan Kettering Cancer Center
Gary K. Schwartz
Gary K. Schwartz Memorial Sloan Kettering Cancer Center
Murray F. Brennan
Murray F. Brennan Memorial Sloan Kettering Cancer Center
Toshihiko Doi
Toshihiko Doi Okayama University
Atsushi Ohtsu
Atsushi Ohtsu Juntendo University

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