World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
94
Citations
53544
World Ranking
918
National Ranking
131

Medicine

D-Index
97
Citations
58953
World Ranking
9071
National Ranking
882

Overview

Stephen Sawcer is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple disciplines primarily within Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to the fields of Immunology, Genetics, Neurology, Molecular Biology, and Infectious Diseases.

The scientist's recent work addresses various complex biomedical topics, with a focus on immune system function and neurological conditions related to infections. Their research encompasses long-term effects of COVID-19, immune cell dynamics, genetic associations with diseases, and cognitive disorders arising in intensive care scenarios.

Their main research topics include:

  • Long-Term Effects of COVID-19
  • T-cell and B-cell Immunology
  • Infectious Encephalopathies and Encephalitis
  • Genetic Associations and Epidemiology
  • Single-cell and spatial transcriptomics
  • Multiple Sclerosis Research Studies
  • Intensive Care Unit Cognitive Disorders

They have published extensively in several high-impact scientific journals. Frequent publication venues are:

  • Nature Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • EClinicalMedicine
  • Journal of Neurology

Among the recent papers authored or co-authored by Stephen Sawcer are:

  • "Complex genetic signatures in immune cells underlie autoimmunity and inform therapy," 2020, Nature Genetics
  • "Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort," 2022, EClinicalMedicine
  • "Mononeuritis multiplex: an unexpectedly frequent feature of severe COVID-19," 2020, Journal of Neurology
  • "Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for 12 immune-mediated diseases," 2022, Nature Genetics
  • "Neuroanatomical substrates of generalized brain dysfunction in COVID-19," 2020, Intensive Care Medicine

They frequently collaborate with other researchers, including Virginia Newcombe, David Menon, James B. Rowe, Doris A. Chatfield, and Joanne Outtrim.

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Risk alleles for multiple sclerosis identified by a genomewide study.

    David A. Hafler;Alastair Compston;Stephen Sawcer;Mark J. Daly

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.

    Aravinthan Varatharaj;Aravinthan Varatharaj;Naomi Thomas;Mark A Ellul;Mark A Ellul;Mark A Ellul;Nicholas W S Davies

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort

    Caroline H. Williams-Gray;Jonathan R. Evans;An Goris;An Goris;Thomas Foltynie

  • Multiple Sclerosis Severity Score: Using disability and disease duration to rate disease severity

    R. H.S.R. Roxburgh;S. R. Seaman;T. Masterman;A. E. Hensiek

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D M Evans;Spencer Cca.;J J Pointon;Z Su

  • Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

    Philip L De Jager;Philip L De Jager;Xiaoming Jia;Joanne Wang;Paul I W de Bakker

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • Interleukin 7 receptor α chain (IL7R) shows allelic and functional association with multiple sclerosis

    Simon G. Gregory;Silke Schmidt;Puneet Seth;Jorge R. Oksenberg

  • A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

    Stephen Sawcer;Hywel B. Jones;Robert Feakes;Julia Gray

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D.M. Evans;C.C.A. Spencer;J.J. Pointon;Z. Su

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

Frequent Co-Authors

Alastair Compston
Alastair Compston University of Cambridge
An Goris
An Goris KU Leuven
David A. Hafler
David A. Hafler Yale University
Jorge R. Oksenberg
Jorge R. Oksenberg University of California, San Francisco
Stephen L. Hauser
Stephen L. Hauser University of California, San Francisco
Lisa F. Barcellos
Lisa F. Barcellos University of California, Berkeley
Philip L. De Jager
Philip L. De Jager Columbia University
Sarah Hunt
Sarah Hunt European Bioinformatics Institute
Peter Donnelly
Peter Donnelly University of Oxford
Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust

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