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Immunology
Germany
2026
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Medicine
Germany
2023

D-Index & Metrics

Immunology

D-Index
128
Citations
109787
World Ranking
250
National Ranking
10

Medicine

D-Index
128
Citations
109785
World Ranking
2636
National Ranking
130

Research.com Recognitions

  • 2026 - Research.com Immunology in Germany Leader Award
  • 2023 - Research.com Immunology in Germany Leader Award
  • 2023 - Research.com Medicine in Germany Leader Award
  • 2022 - Research.com Immunology in Germany Leader Award
  • 2016 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology

Overview

Eicke Latz is affiliated with the University of Bonn in Germany and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their publication record spans various subfields including molecular biology, immunology, physiology, neurology, and epidemiology.

Their research topics primarily focus on inflammasome and immune disorders, neuroinflammation and neurodegeneration mechanisms, immune response and inflammation, interferon and immune responses, immune cells in cancer, Alzheimer's disease research and treatments, and tryptophan and brain disorders.

Significant publication venues for this scientist include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Cell Reports
  • Nature Communications
  • The Journal of Experimental Medicine

Frequent co-authors collaborating with Eicke Latz are:

  • Michael T. Heneka
  • Susanne V. Schmidt
  • Matthew Mangan
  • Róisín M. McManus
  • Mario Lauterbach

Among notable recent papers where Eicke Latz contributed are:

  • Defining trained immunity and its role in health and disease, 2020, Nature Reviews. Immunology
  • Necroptosis, pyroptosis and apoptosis: an intricate game of cell death, 2021, Cellular and Molecular Immunology
  • Immediate and long-term consequences of COVID-19 infections for the development of neurological disease, 2020, Alzheimer's Research & Therapy
  • Trained immunity, tolerance, priming and differentiation: distinct immunological processes, 2020, Nature Immunology
  • Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes, 2021, Cell

In 2016, Eicke Latz received recognition from the German National Academy of Sciences Leopoldina in the field of Microbiology and Immunology.

Best Publications

  • Neuroinflammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

  • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

    Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois

  • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

    Veit Hornung;Franz G. Bauernfeind;Annett Halle;Eivind O. Samstad;Eivind O. Samstad

  • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

    Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe

  • Activation and regulation of the inflammasomes

    Eicke Latz;T. Sam Xiao;Andrea Stutz

  • Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

    Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri

  • AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC

    Veit Hornung;Veit Hornung;Andrea Ablasser;Andrea Ablasser;Marie Charrel-Dennis;Franz G. Bauernfeind;Franz G. Bauernfeind

  • NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice

    Michael T. Heneka;Markus P. Kummer;Andrea Stutz;Andrea Delekate

  • The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

    Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart

  • A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

    Rebecca C Coll;Avril A B Robertson;Jae Jin Chae;Sarah C Higgins

  • Trained immunity: A program of innate immune memory in health and disease

    Mihai G. Netea;Leo A. B. Joosten;Eicke Latz;Kingston H. G. Mills

  • Defining trained immunity and its role in health and disease

    Mihai G. Netea;Mihai G. Netea;Jorge Domínguez-Andrés;Luis B. Barreiro;Luis B. Barreiro;Triantafyllos Chavakis;Triantafyllos Chavakis

  • Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

    Jia Xue;Susanne V. Schmidt;Jil Sander;Astrid Draffehn

  • Targeting the NLRP3 inflammasome in inflammatory diseases

    Matthew S J Mangan;Matthew S J Mangan;Edward J Olhava;William R Roush;H Martin Seidel

  • Necroptosis, pyroptosis and apoptosis: an intricate game of cell death.

    Damien Bertheloot;Eicke Latz;Eicke Latz;Eicke Latz;Bernardo S. Franklin

  • IFI16 is an innate immune sensor for intracellular DNA.

    Leonie Unterholzner;Sinead E. Keating;Marcin Baran;Kristy A. Horan

  • TLR9 signals after translocating from the ER to CpG DNA in the lysosome

    Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald

  • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

    Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen

  • LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

    Katherine A. Fitzgerald;Daniel C. Rowe;Betsy J. Barnes;Daniel R. Caffrey

  • Innate immune activation in neurodegenerative disease

    Michael T. Heneka;Markus P. Kummer;Eicke Latz

  • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.

    Vijay A.K. Rathinam;Zhaozhao Jiang;Stephen N. Waggoner;Shrutie Sharma

  • Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (Nature (2010) 464 (1357-1361))

    Peter Duewell;Hajime Kono;Katey J. Rayner;Cherilyn M. Sirois

Frequent Co-Authors

Douglas T. Golenbock
Douglas T. Golenbock University of Massachusetts Chan Medical School
Michael T. Heneka
Michael T. Heneka University Hospital Bonn
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Terje Espevik
Terje Espevik Norwegian University of Science and Technology
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Ann Marshak-Rothstein
Ann Marshak-Rothstein University of Massachusetts Chan Medical School
Mihai G. Netea
Mihai G. Netea Radboud University
Ashley Mansell
Ashley Mansell Hudson Institute of Medical Research
Egil Lien
Egil Lien University of Massachusetts Chan Medical School

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