What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
His main research concerns Receptor, TLR4, Immunology, Toll-like receptor and Signal transduction.
The Receptor study combines topics in areas such as Tumor necrosis factor alpha and Monocyte.
His research links Microbiology with TLR4.
His work is dedicated to discovering how Immunology, Internal medicine are connected with Endocrinology and other disciplines.
His work carried out in the field of Toll-like receptor brings together such families of science as TLR2, CD14 and Cell biology.
His research investigates the connection between Signal transduction and topics such as Proinflammatory cytokine that intersect with issues in Heat shock protein and Surgery.
His most cited work include:
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2205 citations)
- Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2 (1140 citations)
- TLR9 signals after translocating from the ER to CpG DNA in the lysosome (1140 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Immunology, Cell biology, Innate immune system, TLR4 and Receptor.
His work in Immunology addresses subjects such as Virology, which are connected to disciplines such as Adjuvant, Antibody, Antigen and Interleukin 10.
His study looks at the intersection of Cell biology and topics like Caspase 8 with Necroptosis.
His work investigates the relationship between Innate immune system and topics such as Inflammasome that intersect with problems in Proinflammatory cytokine, Endocrinology, Yersinia pestis and Effector.
His TLR4 study focuses on TLR2 in particular.
Egil Lien works mostly in the field of Toll-like receptor, limiting it down to concerns involving CD14 and, occasionally, Lipopolysaccharide and Chinese hamster ovary cell.
He most often published in these fields:
- Immunology (45.34%)
- Cell biology (32.92%)
- Innate immune system (34.16%)
What were the highlights of his more recent work (between 2014-2021)?
- Inflammation (32.92%)
- Inflammasome (31.68%)
- Cell biology (32.92%)
In recent papers he was focusing on the following fields of study:
Inflammation, Inflammasome, Cell biology, Innate immune system and Pyroptosis are his primary areas of study.
His Inflammation study integrates concerns from other disciplines, such as Endocrinology and Immunity.
His research in Immunity focuses on subjects like Early detection, which are connected to Receptor.
His work in Receptor covers topics such as Viral envelope which are related to areas like TLR4.
His Inflammasome research includes elements of Tumor necrosis factor alpha, Pathogenesis, Caspase, Systemic inflammation and Virulence.
His Innate immune system research also works with subjects such as
- Microbiology which connect with Yersinia pestis,
- Secretion most often made with reference to Effector.
Between 2014 and 2021, his most popular works were:
- Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (208 citations)
- Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (208 citations)
- Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants (80 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
His primary scientific interests are in Effector, Cell biology, Innate immune system, Inflammasome and Pyroptosis.
His work deals with themes such as Yersinia pseudotuberculosis, Secretion, NLRC4, Microbiology and Yersinia pestis, which intersect with Effector.
The study incorporates disciplines such as Myeloid Differentiation Factor 88, Toll-like receptor and TRIF in addition to Cell biology.
His Innate immune system research is multidisciplinary, relying on both Pyrin domain, Hypoxia, Pulmonary vasculature, Pulmonary hypertension and Macrophage.
Egil Lien has included themes like T cell, Premature death, Viability assay, Adjuvant and Monophosphoryl Lipid A in his Inflammasome study.
His biological study spans a wide range of topics, including Cleavage, RIPK1, Caspase 8, Regulator and IκB kinase.
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