T. Kendall Harden

Research.com Recognitions

• 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

  Michael R. Elliott;Faraaz B. Chekeni;Paul C. Trampont;Eduardo R. Lazarowski

  1829
  Citations

• Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules.

  Eduardo R. Lazarowski;Richard C. Boucher;T. Kendall Harden

  691
  Citations

• Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.

  Robert A. Nicholas;William C. Watt;Eduardo R. Lazarowski;Qing Li

  510
  Citations

• P2-Purinergic Receptors: Subtype-Associated Signaling Responses and Structure

  T K Harden;J L Boyer;R A Nicholas

  496
  Citations

• Towards a revised nomenclature for P1 and P2 receptors

  Bertil B. Fredholm;Maria P. Abbracchio;Geoffrey Burnstock;George R. Dubyak

  468
  Citations

• Constitutive Release of ATP and Evidence for Major Contribution of Ecto-nucleotide Pyrophosphatase and Nucleoside Diphosphokinase to Extracellular Nucleotide Concentrations

  Eduardo R. Lazarowski;Richard C. Boucher;T. Kendall Harden

  460
  Citations

• Direct Demonstration of Mechanically Induced Release of Cellular UTP and Its Implication for Uridine Nucleotide Receptor Activation

  Eduardo R. Lazarowski;László Homolya;Richard C. Boucher;T. Kendall Harden

  425
  Citations

• The experimental power of FR900359 to study Gq-regulated biological processes

  Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  386
  Citations

• Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization.

  S B Masters;M W Martin;T K Harden;J H Brown

  372
  Citations

• Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor

  Joel B. Schachter;Qing Li;José L. Boyer;Robert A. Nicholas

  354
  Citations

• Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.

  Eduardo R. Lazarowski;William C. Watt;M. Jackson Stutts;Richard C. Boucher

  350
  Citations

• Kinetic Scaffolding Mediated by a Phospholipase C–β and Gq Signaling Complex

  Gary L. Waldo;Tiffany K. Ricks;Stephanie N. Hicks;Matthew L. Cheever

  288
  Citations

• Beta gamma-subunit activation of G-protein-regulated phospholipase C.

  J.L. Boyer;G.L. Waldo;T.K. Harden

  278
  Citations

• beta-Adrenergic receptor involvement in 6-hydroxydopamine-induced supersensitivity in rat cerebral cortex.

  JR Sporn;TK Harden;BB Wolfe;PB Molinoff

  273
  Citations

• Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization.

  G L Waldo;J K Northup;J P Perkins;T K Harden

  266
  Citations

• Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate

  José L Boyer;Arvind Mohanram;Emidio Camaioni;Kenneth A Jacobson

  247
  Citations

• Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization.

  J R Hepler;H S Earp;T K Harden

  237
  Citations

• Agonist Action of Adenosine Triphosphates at the Human P2Y1 Receptor

  R. Kyle Palmer;José L. Boyer;Joel B. Schachter;Robert A. Nicholas

  234
  Citations

• PLC-epsilon: a shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling.

  Michele R Wing;David M Bourdon;T Kendall Harden

  232
  Citations

• The phospholipase C isozymes and their regulation.

  Aurelie Gresset;John Sondek;T. Kendall Harden

  230
  Citations

• General and Versatile Autoinhibition of PLC Isozymes

  Stephanie N. Hicks;Mark R. Jezyk;Svetlana Gershburg;Jason P. Seifert

  218
  Citations