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Biology and Biochemistry

D-Index
52
Citations
9039
World Ranking
16743
National Ranking
6913

Overview

Victor Faundez is affiliated with Emory University in the United States and has a research focus primarily within the field of Biochemistry, Genetics and Molecular Biology, with 95 publications contributing to this domain. Their work spans several subfields including Molecular Biology, Genetics, Nutrition and Dietetics, Cell Biology, and Physiology.

The research topics that Faundez has engaged with prominently include Mitochondrial Function and Pathology, Genetics and Neurodevelopmental Disorders, Trace Elements in Health, Congenital Heart Defects Research, Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's Disease Research and Treatments, and RNA Modifications and Cancer.

Faundez has published extensively, with recent papers covering a range of topics in neuroscience and molecular biology. Notable publications include:

  • "Shared mechanisms across the major psychiatric and neurodegenerative diseases," 2022, Nature Communications
  • "Rare Genetic Diseases: Nature's Experiments on Human Development," 2020, iScience
  • "Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content," 2020, Journal of Neuroscience
  • "Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus," 2021, Journal of Neuroscience
  • "Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism," 2020, iScience

The scientist has collaborated frequently with other researchers, including Erica Werner, Avanti Gokhale, Stephanie A. Zlatic, Duc M. Duong, and Gary J. Bassell, reflecting a significant degree of teamwork in these interdisciplinary studies.

Faundez's research has appeared in multiple venues, with a notable number of publications in bioRxiv (Cold Spring Harbor Laboratory), iScience, Biological Psychiatry, Journal of Neuroscience, and STAR Protocols. These venues demonstrate a strong presence in both preprint repositories and peer-reviewed journals across neuroscience and molecular biology disciplines.

Best Publications

  • BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes.

    Cédric Delevoye;Xavier Heiligenstein;Léa Ripoll;Floriane Gilles-Marsens

  • Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

    Kanyan Xiao;David F. Allison;Kathleen M. Buckley;Margaret D. Kottke

  • p120-Catenin Regulates Clathrin-dependent Endocytosis of VE-Cadherin

    Kanyan Xiao;Jennifer Garner;Kathleen M. Buckley;Peter A. Vincent

  • A function for the AP3 coat complex in synaptic vesicle formation from endosomes.

    Victor Faúndez;Jim-Tong Horng;Regis B Kelly

  • p120-catenin binding masks an endocytic signal conserved in classical cadherins.

    Benjamin A. Nanes;Christine Chiasson-MacKenzie;Anthony M. Lowery;Noboru Ishiyama

  • Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells.

    Kanyan Xiao;David F. Allison;Margaret D. Kottke;Susan Summers

  • The Endo-Lysosomal Sorting Machinery Interacts with the Intermediate Filament Cytoskeleton

    Melanie L. Styers;Gloria Salazar;Rachal Love;Andrew A. Peden

  • Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes.

    Ariana Mullin;Avanti S Gokhale;A. Moreno-De-Luca;S. Sanyal;S. Sanyal

  • A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.

    Etienne A. Cartier;Leonardo A. Parra;Tracy B. Baust;Marisol Quiroz

  • Neuronal and non-neuronal functions of the AP-3 sorting machinery.

    Karen Newell-Litwa;Eunju Seong;Margit Burmeister;Victor Faundez

  • Pemphigus Vulgaris IgG-induced Desmoglein-3 Endocytosis and Desmosomal Disassembly Are Mediated by a Clathrin-and Dynamin-independent Mechanism

    Emmanuella Delva;Jean Marie Jennings;Cathárine C. Calkins;Margaret D. Kottke

  • BLOC-1 Complex Deficiency Alters the Targeting of Adaptor Protein Complex-3 Cargoes

    G. Salazar;B. Craige;M. L. Styers;K. A. Newell-Litwa

  • Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin–radixin–moesin network

    Patricia Perez-Cornejo;Avanti Gokhale;Charity Duran;Yuanyuan Cui

  • AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells.

    Gloria Salazar;Rachal Love;Melanie L. Styers;Erica Werner

  • A Mutation of β-Actin That Alters Depolymerization Dynamics Is Associated with Autosomal Dominant Developmental Malformations, Deafness, and Dystonia

    Vincent Procaccio;Gloria Salazar;Shoichiro Ono;Melanie L. Styers

  • Phosphatidylinositol-4-Kinase Type II Alpha Contains an AP-3-sorting Motif and a Kinase Domain That Are Both Required for Endosome Traffic

    Branch Craige;Gloria Salazar;Victor Faundez

  • Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells.

    Gloria Salazar;Branch Craige;Rachal Love;Daniel Kalman

  • ADP Ribosylation Factor 1 Is Required for Synaptic Vesicle Budding in PC12 Cells

    Victor Faúndez;Jim-Tong Horng;Regis B. Kelly

  • The Zinc Transporter ZnT3 Interacts with AP-3 and It Is Preferentially Targeted to a Distinct Synaptic Vesicle Subpopulation

    Gloria Salazar;Rachal Love;Erica Werner;Michele M. Doucette

  • A v-SNARE participates in synaptic vesicle formation mediated by the AP3 adaptor complex.

    Natalie Salem;Victor Faúndez;Jim-Tong Horng;Regis B. Kelly

Frequent Co-Authors

Andrew P. Kowalczyk
Andrew P. Kowalczyk Emory University
Yoland Smith
Yoland Smith Emory University
Regis B. Kelly
Regis B. Kelly University of California, San Francisco
Gary J. Bassell
Gary J. Bassell Emory University
Allan I. Levey
Allan I. Levey Emory University
Bruce H. Wainer
Bruce H. Wainer Emory University
H. Criss Hartzell
H. Criss Hartzell Emory University
Esteban C. Dell'Angelica
Esteban C. Dell'Angelica University of California, Los Angeles
David A. Lewis
David A. Lewis University of Pittsburgh
Carrie E. Bearden
Carrie E. Bearden University of California, Los Angeles

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