Pierre D. McCrea mainly focuses on Cell biology, Catenin, Wnt signaling pathway, Cadherin and Molecular biology. Cell biology is often connected to Biochemistry in his work. His Catenin research is under the purview of Signal transduction.
The study incorporates disciplines such as Receptor and Mesenchyme in addition to Wnt signaling pathway. Pierre D. McCrea has researched Cadherin in several fields, including Vinculin, Cytoskeleton, Tyrosine kinase and Proto-oncogene tyrosine-protein kinase Src. His Molecular biology research includes elements of Cell surface receptor, Receptor tyrosine kinase, SH2 domain and Mesoderm.
His scientific interests lie mostly in Cell biology, Catenin, Wnt signaling pathway, Cadherin and Molecular biology. His biological study spans a wide range of topics, including Genetics and Cytoskeleton. Pierre D. McCrea has included themes like Adherens junction, Actin cytoskeleton, Cell adhesion and Cell adhesion molecule in his Catenin study.
His Wnt signaling pathway research entails a greater understanding of Signal transduction. His Cadherin research incorporates themes from Cytoplasm, Axis specification, Immunoprecipitation and Blastula. His Molecular biology research includes themes of Desmosomal Cadherins, RCOR1, Small GTPase, Nuclear localization sequence and Armadillo repeats.
His main research concerns Cell biology, Wnt signaling pathway, Catenin, Cancer and Beta-catenin. He combines subjects such as Alveolar cells and Kidney, Nephron with his study of Cell biology. As a part of the same scientific study, Pierre D. McCrea usually deals with the Wnt signaling pathway, concentrating on Cancer research and frequently concerns with Stem cell and Intestinal mucosa.
His Catenin study combines topics in areas such as Molecular biology and Cadherin. His Colorectal cancer and Adenomatous polyposis coli study, which is part of a larger body of work in Cancer, is frequently linked to Regulator, bridging the gap between disciplines. The Beta-catenin study which covers LRP6 that intersects with LRP5 and Transactivation.
Pierre D. McCrea mostly deals with Wnt signaling pathway, Cell biology, Beta-catenin, Catenin and Molecular biology. His Wnt signaling pathway study incorporates themes from Cancer research, Intestinal mucosa, Transplantation and Cell nucleus. His research in the fields of LRP6 and LRP5 overlaps with other disciplines such as Regulation of gene expression and EZH2.
His Beta-catenin research is multidisciplinary, incorporating elements of Carcinogenesis, Radioresistance and Stem cell. The Catenin study combines topics in areas such as SOX2, Cadherin, Adherens junction and RCOR1. His research in Molecular biology intersects with topics in SOX9, Lung, Small GTPase and Fibroblast growth factor.
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Interactions between Sox9 and β-catenin control chondrocyte differentiation
Haruhiko Akiyama;Jon P. Lyons;Yuko Mori-Akiyama;Xiaohong Yang.
Genes & Development (2004)
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin.
Pierre D. Mccrea;Christoph W. Turck;Barry Gumbiner.
Overexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos
Janet Heasman;Aaron Crawford;Kim Goldstone;Peggy Garner-Hamrick.
Telomerase modulates Wnt signalling by association with target gene chromatin
Jae Il Park;Andrew S. Venteicher;Ji Yeon Hong;Jinkuk Choi.
Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling.
Noriko Funayama;François Fagotto;Pierre McCrea;Barry M. Gumbiner.
Journal of Cell Biology (1995)
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.
Albert B. Reynolds;Juliet Daniel;Pierre D. Mccrea;Margaret J. Wheelock.
Molecular and Cellular Biology (1994)
The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties.
Mark Peifer;Pierre D. McCrea;Kathleen J. Green;Eric Wieschaus.
Journal of Cell Biology (1992)
Catenins as mediators of the cytoplasmic functions of cadherins
Barry M. Gumbiner;Pierre D. McCrea.
Journal of Cell Science (1993)
Kaiso/p120-Catenin and TCF/β-Catenin Complexes Coordinately Regulate Canonical Wnt Gene Targets
Jae Il Park;Jae Il Park;Si Wan Kim;Jon P. Lyons;Jon P. Lyons;Hong Ji.
Developmental Cell (2005)
Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure.
P D McCrea;B M Gumbiner.
Journal of Biological Chemistry (1991)
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