What is he best known for?
The fields of study he is best known for:
- Wnt signaling pathway
- Phosphorylation
- Genetics
Pierre D. McCrea mainly focuses on Cell biology, Catenin, Wnt signaling pathway, Cadherin and Molecular biology.
Cell biology is often connected to Biochemistry in his work.
His Catenin research is under the purview of Signal transduction.
The study incorporates disciplines such as Receptor and Mesenchyme in addition to Wnt signaling pathway.
Pierre D. McCrea has researched Cadherin in several fields, including Vinculin, Cytoskeleton, Tyrosine kinase and Proto-oncogene tyrosine-protein kinase Src.
His Molecular biology research includes elements of Cell surface receptor, Receptor tyrosine kinase, SH2 domain and Mesoderm.
His most cited work include:
- Interactions between Sox9 and β-catenin control chondrocyte differentiation (604 citations)
- Overexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos (595 citations)
- A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. (561 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Catenin, Wnt signaling pathway, Cadherin and Molecular biology.
His biological study spans a wide range of topics, including Genetics and Cytoskeleton.
Pierre D. McCrea has included themes like Adherens junction, Actin cytoskeleton, Cell adhesion and Cell adhesion molecule in his Catenin study.
His Wnt signaling pathway research entails a greater understanding of Signal transduction.
His Cadherin research incorporates themes from Cytoplasm, Axis specification, Immunoprecipitation and Blastula.
His Molecular biology research includes themes of Desmosomal Cadherins, RCOR1, Small GTPase, Nuclear localization sequence and Armadillo repeats.
He most often published in these fields:
- Cell biology (98.02%)
- Catenin (78.22%)
- Wnt signaling pathway (62.38%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (98.02%)
- Wnt signaling pathway (62.38%)
- Catenin (78.22%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Wnt signaling pathway, Catenin, Cancer and Beta-catenin.
He combines subjects such as Alveolar cells and Kidney, Nephron with his study of Cell biology.
As a part of the same scientific study, Pierre D. McCrea usually deals with the Wnt signaling pathway, concentrating on Cancer research and frequently concerns with Stem cell and Intestinal mucosa.
His Catenin study combines topics in areas such as Molecular biology and Cadherin.
His Colorectal cancer and Adenomatous polyposis coli study, which is part of a larger body of work in Cancer, is frequently linked to Regulator, bridging the gap between disciplines.
The Beta-catenin study which covers LRP6 that intersects with LRP5 and Transactivation.
Between 2012 and 2021, his most popular works were:
- PAF and EZH2 Induce Wnt/β-Catenin Signaling Hyperactivation (117 citations)
- Lung epithelial branching program antagonizes alveolar differentiation (113 citations)
- FOXKs Promote Wnt/β-Catenin Signaling by Translocating DVL into the Nucleus (65 citations)
In his most recent research, the most cited papers focused on:
- Wnt signaling pathway
- Genetics
- Phosphorylation
Pierre D. McCrea mostly deals with Wnt signaling pathway, Cell biology, Beta-catenin, Catenin and Molecular biology.
His Wnt signaling pathway study incorporates themes from Cancer research, Intestinal mucosa, Transplantation and Cell nucleus.
His research in the fields of LRP6 and LRP5 overlaps with other disciplines such as Regulation of gene expression and EZH2.
His Beta-catenin research is multidisciplinary, incorporating elements of Carcinogenesis, Radioresistance and Stem cell.
The Catenin study combines topics in areas such as SOX2, Cadherin, Adherens junction and RCOR1.
His research in Molecular biology intersects with topics in SOX9, Lung, Small GTPase and Fibroblast growth factor.
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