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Molecular Biology

D-Index
59
Citations
9542
World Ranking
2039
National Ranking
1012

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michelle Craig Barton is affiliated with The University of Texas MD Anderson Cancer Center in the United States. The primary fields of study for this researcher focus on Biochemistry, Genetics and Molecular Biology, with additional work grounded in Medicine. Their research extends into several subfields including Molecular Biology, Oncology, Physiology, Immunology, and Biomedical Engineering.

The main topics addressed in their work include:

  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors
  • RNA Research and Splicing
  • Ubiquitin and proteasome pathways
  • 3D Printing in Biomedical Research
  • Gut microbiota and health
  • RNA modifications and cancer

Recent publications attributed to this researcher reflect a focus on cancer biology and molecular pathways relevant to tumor progression and immunity. Notable papers include:

  • "Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis," 2021, published in Cancer Discovery
  • "Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy," 2020, published in Cancer Immunology Research
  • "Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils," 2021, published in Proceedings of the National Academy of Sciences
  • "CD8+ T cells inhibit metastasis and CXCL4 regulates its function," 2021, published in British Journal of Cancer
  • "TMEM9-v-ATPase Activates Wnt/β-Catenin Signaling Via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis," 2020, published in Hepatology

Frequently collaborating with others in their field, this researcher has coauthored multiple papers with:

  • Kendra Allton
  • Guillermina Lozano
  • Sabrina A. Stratton
  • Helen Piwnica-Worms
  • Kirk Leifso

Their work has been published repeatedly in several venues, with notable numbers of publications in:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JAMA Pediatrics
  • Advanced Science
  • Blood

Recognition for their contributions includes election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.

Best Publications

  • TRIM24 links a non-canonical histone signature to breast cancer

    Wen Wei Tsai;Zhanxin Wang;Teresa T. Yiu;Teresa T. Yiu;Kadir C. Akdemir

  • ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

    Hong Wen;Yuanyuan Li;Yuanxin Xi;Shiming Jiang

  • Kaiso/p120-Catenin and TCF/β-Catenin Complexes Coordinately Regulate Canonical Wnt Gene Targets

    Jae Il Park;Jae Il Park;Si Wan Kim;Jon P. Lyons;Jon P. Lyons;Hong Ji

  • Trim24 targets endogenous p53 for degradation

    Kendra Allton;Abhinav K. Jain;Hans-Martin Herz;Wen-Wei Tsai;Wen-Wei Tsai

  • Hypoxia induces a novel signature of chromatin modifications and global repression of transcription.

    Amber Buescher Johnson;Nicholas Denko;Michelle Craig Barton

  • p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

    Abhinav K. Jain;Kendra Allton;Michelina Iacovino;Elisabeth Mahen

  • p53-Mediated repression of alpha-fetoprotein gene expression by specific DNA binding

    Kathleen C. Lee;Alison J. Crowe;Michelle Craig Barton

  • 3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells

    Gilbert-A. Keller;Michelle C. Barton;David J. Shapiro;S. J. Singer

  • UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II

    Davy A. P. Rockx;Rebecca Mason;Rebecca Mason;Anneke van Hoffen;Michelle Craig Barton

  • LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56

    Abhinav K. Jain;Yuanxin Xi;Ryan McCarthy;Kendra Allton

  • The p63 Protein Isoform ΔNp63α Inhibits Epithelial-Mesenchymal Transition in Human Bladder Cancer Cells ROLE OF MIR-205

    Mai N. Tran;Woonyoung Choi;Matthew F. Wszolek;Neema Navai

  • Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation

    Xi Zhang;Kaori Tanaka;Jiusheng Yan;Jing Li;Jing Li

  • Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors

    Melissa M. Singh;Christa A. Manton;Christa A. Manton;Krishna P. Bhat;Wen Wei Tsai

  • Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.

    Wylie S. Palmer;Guillaume Poncet-Montange;Gang Liu;Alessia Petrocchi

  • TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

    Chunlei Jin;Yue Lu;Jaroslav Jelinek;Shoudan Liang

  • Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

    Zhifang Xie;Hai Zhang;Wenwei Tsai;Ye Zhang

  • Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

    Marion Dejosez;Stuart S. Levine;Garrett M. Frampton;Warren A. Whyte

  • Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis

    Hector L. Franco;Hector L. Franco;Anusha Nagari;Venkat S. Malladi;Wenqian Li

  • Hypoxia-induced and stress-specific changes in chromatin structure and function.

    Amber Buescher Johnson;Michelle Craig Barton

  • P53: Emerging roles in stem cells, development and beyond

    Abhinav K. Jain;Michelle Craig Barton

Frequent Co-Authors

Sharon Y.R. Dent
Sharon Y.R. Dent The University of Texas MD Anderson Cancer Center
Xiaobing Shi
Xiaobing Shi Van Andel Institute
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center
David J. Shapiro
David J. Shapiro University of Illinois at Urbana-Champaign
Pierre D. McCrea
Pierre D. McCrea The University of Texas MD Anderson Cancer Center
Austin J. Cooney
Austin J. Cooney Baylor College of Medicine
Khandan Keyomarsi
Khandan Keyomarsi The University of Texas MD Anderson Cancer Center
Jeffrey T. Chang
Jeffrey T. Chang The University of Texas Health Science Center at Houston
Timothy P. Heffernan
Timothy P. Heffernan The University of Texas MD Anderson Cancer Center
Don L. Gibbons
Don L. Gibbons The University of Texas MD Anderson Cancer Center

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