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Molecular Biology

D-Index
54
Citations
13080
World Ranking
2312
National Ranking
1140

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Sharon Y.R. Dent is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their scholarly work primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a significant emphasis on Molecular Biology. Other subfields of study include Oncology, Plant Science, Neurology, and Cancer Research.

The main research topics of Sharon Y.R. Dent include:

  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Histone Deacetylase Inhibitors Research
  • RNA modifications and cancer
  • Neuroblastoma Research and Treatments

Their recent papers reflect ongoing contributions to the understanding of molecular mechanisms and cancer biology. Notable publications include:

  • Now open: Evolving insights to the roles of lysine acetylation in chromatin organization and function, 2022, Molecular Cell
  • Complex functions of Gcn5 and Pcaf in development and disease, 2020, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  • Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis, 2020, Cancer Research
  • Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms, 2021, Epigenetics & Chromatin
  • Targeting the SAGA and ATAC Transcriptional Coactivator Complexes in MYC-Driven Cancers, 2020, Cancer Research

Frequent co-authors collaborating with Sharon Y.R. Dent include Evangelia Koutelou, Kevin Lin, Yue Lu, Xianghong Kuang, and Joseph C. Y. Chen. The scientist regularly publishes in venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Molecular Cell, Science Advances, and Frontiers in Epigenetics and Epigenomics.

Sharon Y.R. Dent was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • New nomenclature for chromatin-modifying enzymes.

    C. David Allis;Shelley L. Berger;Jacques Cote;Sharon R Dent

  • Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

    Qihuang Jin;Li Rong Yu;Lifeng Wang;Zhijing Zhang

  • HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin

    Xiaohong Zhang;Zhigang Yuan;Yingtao Zhang;Sarah Yong

  • Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

    Scott D. Briggs;Mary Bryk;Brian D. Strahl;Wang L. Cheung

  • Chromatin modifiers and remodellers: regulators of cellular differentiation

    Taiping Chen;Sharon Y. R. Dent

  • Cross-regulation of histone modifications

    John A Latham;Sharon Y R Dent

  • DANPOS: dynamic analysis of nucleosome position and occupancy by sequencing.

    Kaifu Chen;Yuanxin Xi;Xuewen Pan;Zhaoyu Li

  • AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.

    Yuanyuan Li;Hong Wen;Yuanxin Xi;Kaori Tanaka

  • Multiple faces of the SAGA complex

    Evangelia Koutelou;Calley L. Hirsch;Sharon Y.R. Dent

  • The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

    Alejandra Loyola;Alejandra Loyola;Alejandra Loyola;Hideaki Tagami;Tiziana Bonaldi;Danièle Roche

  • Regulation of the osteoblast‐specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

    Krishna M Sinha;Hideyo Yasuda;Madelene M Coombes;Sharon Y R Dent

  • Gcn5 and SAGA Regulate Shelterin Protein Turnover and Telomere Maintenance

    Boyko S. Atanassov;Yvonne A. Evrard;Asha S. Multani;Zhijing Zhang

  • R loops stimulate genetic instability of CTG·CAG repeats

    Yunfu Lin;Sharon Y. R. Dent;John H. Wilson;Robert D. Wells

  • Transcriptional repression by Tup1-Ssn6

    Tania M. MalavéT.M. Malavé;Sharon Y.R. DentS.Y. Dent

  • Histone modifying enzymes and cancer: going beyond histones

    Ke Zhang;Sharon Y R Dent

  • Chromatin “Prepattern” and Histone Modifiers in a Fate Choice for Liver and Pancreas

    Cheng Ran Xu;Philip A. Cole;David J. Meyers;Jay Kormish;Jay Kormish

  • c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.

    Xiaohui Liu;Jerusalem Tesfai;Yvonne A. Evrard;Sharon Y.R. Dent

  • The Set1 Methyltransferase Opposes Ipl1 Aurora Kinase Functions in Chromosome Segregation

    Ke Zhang;Wenchu Lin;John A. Latham;Gary M. Riefler

  • Loss of Gcn5 Acetyltransferase Activity Leads to Neural Tube Closure Defects and Exencephaly in Mouse Embryos

    Ping Bu;Yvonne A. Evrard;Yvonne A. Evrard;Guillermina Lozano;Sharon Y Roth Dent

  • Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot permit commercial exploitation without specific permission.

    Krishna M Sinha;Hideyo Yasuda;Madelene M Coombes;Sharon Yr Dent

Frequent Co-Authors

Yue Lu
Yue Lu The University of Texas MD Anderson Cancer Center
Michelle Craig Barton
Michelle Craig Barton The University of Texas MD Anderson Cancer Center
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
Xiaobing Shi
Xiaobing Shi Van Andel Institute
Michael P. Washburn
Michael P. Washburn University of Kansas
Deyu Fang
Deyu Fang Northwestern University
Jason Roszik
Jason Roszik The University of Texas MD Anderson Cancer Center
Jerry L. Workman
Jerry L. Workman Stowers Institute for Medical Research
Jianjun Shen
Jianjun Shen The University of Texas MD Anderson Cancer Center
Richard D. Wood
Richard D. Wood The University of Texas MD Anderson Cancer Center

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