World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
13257
World Ranking
12476
National Ranking
5339

Overview

Deyu Fang is a researcher affiliated with Northwestern University in the United States. Their work spans multiple interdisciplinary domains, primarily within Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The subfields in which they have made notable contributions include Immunology, Molecular Biology, Oncology, Cell Biology, and Epidemiology.

Their research covers a broad range of topics focusing on immune mechanisms and cellular pathways, including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Endoplasmic Reticulum Stress and Disease
  • Ubiquitin and proteasome pathways
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune cells in cancer

Deyu Fang has collaborated frequently with several co-authors, indicative of active engagement in a collaborative research environment. Among these co-authors are Huiping Liu, Juncheng Wei, Nikita Mani, Elena Montauti, and Yana Zhang.

Their recent scholarly contributions include papers published in various reputable journals and scientific venues:

  • "Performance simulation method and state of health estimation for lithium-ion batteries based on aging-effect coupling model," 2023, Green Energy and Intelligent Transportation
  • "Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2," 2022, Nature Communications
  • "IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP," 2022, Journal of Allergy and Clinical Immunology
  • "CRISPR screen in regulatory T cells reveals modulators of Foxp3," 2020, Nature
  • "Endoplasmic Reticulum Stress Signaling and the Pathogenesis of Hepatocarcinoma," 2021, International Journal of Molecular Sciences

These publications reflect a multidisciplinary approach, touching on immunology, molecular biology, battery technology simulation, and cellular stress pathways in disease processes.

The scientist regularly publishes in journals and repositories including bioRxiv (Cold Spring Harbor Laboratory), SSRN Electronic Journal, Journal of Clinical Investigation, The Journal of Immunology, and Science Advances.

Best Publications

  • Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response

    Weimin Chen;Zheng Sun;Xiao Jun Wang;Tao Jiang

  • Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

    Hongting Zheng;Hongting Zheng;Samantha A. Whitman;Wei Wu;Wei Wu;Georg T. Wondrak

  • The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

    Tao Jiang;Zheping Huang;Yifeng Lin;Zhigang Zhang

  • Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

    Deyu Fang;Chris Elly;Baixue Gao;Nan Fang

  • Jun Turnover Is Controlled Through JNK-Dependent Phosphorylation of the E3 Ligase Itch

    Min Gao;Tord Labuda;Tord Labuda;Tord Labuda;Ying Xia;Ying Xia;Ying Xia;Ewen Gallagher;Ewen Gallagher;Ewen Gallagher

  • Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase.

    Ling Qiu;Claudio Joazeiro;Nan Fang;Hong-Ying Wang

  • USP22 Antagonizes p53 Transcriptional Activation by Deubiquitinating Sirt1 to Suppress Cell Apoptosis and Is Required for Mouse Embryonic Development

    Zhenghong Lin;Heeyoung Yang;Qingfei Kong;Jinping Li

  • Proteolysis-independent regulation of PI3K by Cbl-b–mediated ubiquitination in T cells

    Deyu Fang;Yun Cai Liu

  • Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

    Tongde Wu;Fei Zhao;Beixue Gao;Can Tan

  • The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice.

    Jinping Zhang;Sang Myeong Lee;Sang Myeong Lee;Stephen Shannon;Beixue Gao;Beixue Gao

  • Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

    Deyu Fang;Hong Ying Wang;Nan Fang;Yoav Altman

  • The Tight Junction-specific Protein Occludin Is a Functional Target of the E3 Ubiquitin-protein Ligase Itch

    Andreas Traweger;Deyu Fang;Yun Cai Liu;Wolfgang Stelzhammer

  • The Roles of SIRT1 in Cancer.

    Zhenghong Lin;Deyu Fang

  • Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

    Quan Qiu;Ze Zheng;Lin Chang;Yuan Si Zhao

  • IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.

    Shengyi Sun;Guojun Shi;Haibo Sha;Yewei Ji

  • Cbl Promotes Ubiquitination of the T Cell Receptor ζ through an Adaptor Function of Zap-70

    Hong Ying Wang;Yoav Altman;Deyu Fang;Chris Elly

  • USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation

    Zhenghong Lin;Heeyoung Yang;Can Tan;Jinping Li

  • TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

    Daniel R. Principe;Brian DeCant;Emman Mascariñas;Elizabeth A. Wayne;Elizabeth A. Wayne

  • CRISPR screen in regulatory T cells reveals modulators of Foxp3.

    Jessica T. Cortez;Elena Montauti;Eric Shifrut;Eric Shifrut;Jovylyn Gatchalian

  • Proteolysis-independent regulation of PI3K by Cbl-bmediated ubiquitination in T cells

    Deyu Fang;Yun-Cai Liu

Frequent Co-Authors

Donna D. Zhang
Donna D. Zhang University of Arizona
Kezhong Zhang
Kezhong Zhang Wayne State University
Hongxin Dong
Hongxin Dong Northwestern University
Li Wang
Li Wang Yale University
Timothy M. Kuzel
Timothy M. Kuzel Rush University Medical Center
Eduardo N. Chini
Eduardo N. Chini Mayo Clinic
Yun-Cai Liu
Yun-Cai Liu La Jolla Institute For Allergy & Immunology
Ying Xia
Ying Xia Fudan University
Jin-Ming Yang
Jin-Ming Yang University of Kentucky
Michael Karin
Michael Karin University of California, San Diego

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