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Molecular Biology

D-Index
48
Citations
17149
World Ranking
2658
National Ranking
1296

Overview

Kezhong Zhang is affiliated with Wayne State University in the United States and has contributed extensively to research in the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work spans multiple subfields, including Molecular Biology, Cell Biology, Health, Toxicology and Mutagenesis, Physiology, and Surgery.

Their research tackles diverse main topics, such as Endoplasmic Reticulum Stress and Disease, Pancreatic function and diabetes, Air Quality and Health Impacts, Adipose Tissue and Metabolism, Climate Change and Health Impacts, Mitochondrial Function and Pathology, and Cystic Fibrosis Research Advances.

Among recent notable publications are:

  • Mechanisms, regulation and functions of the unfolded protein response, 2020, Nature Reviews Molecular Cell Biology
  • Sex-dependent effects of ambient PM2.5 pollution on insulin sensitivity and hepatic lipid metabolism in mice, 2020, Particle and Fibre Toxicology
  • An updated ANGPTL3-4-8 model as a mechanism of triglyceride partitioning between fat and oxidative tissues, 2021, Progress in Lipid Research
  • Top-Down and Bottom-Up Approaches to Environmental Governance in China: Evidence from the River Chief System (RCS), 2020, International Journal of Environmental Research and Public Health
  • Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms, 2020, Proceedings of the National Academy of Sciences

The frequent coauthors collaborating with Kezhong Zhang include:

  • Zhenfeng Song
  • Ren Zhang
  • Hyunbae Kim
  • Qinghua Sun
  • Cuiqing Liu

The scientist has a publication record in multiple recurring venues, including:

  • Environmental Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Proceedings of the National Academy of Sciences
  • The FASEB Journal

Best Publications

  • From endoplasmic-reticulum stress to the inflammatory response

    Kezhong Zhang;Randal J. Kaufman

  • Mechanisms, regulation and functions of the unfolded protein response.

    Claudio Hetz;Kezhong Zhang;Randal J. Kaufman

  • Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response

    Kezhong Zhang;Xiaohua Shen;Jun Wu;Kenjiro Sakaki

  • The unfolded protein response: A stress signaling pathway critical for health and disease

    Kezhong Zhang;Randal J. Kaufman

  • Signaling the Unfolded Protein Response from the Endoplasmic Reticulum

    Kezhong Zhang;Randal J. Kaufman

  • Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

    Jyoti D. Malhotra;Hongzhi Miao;Kezhong Zhang;Anna Wolfson

  • The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

    Li Chung Hsu;Jin Mo Park;Kezhong Zhang;Jun Li Luo

  • The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis

    Kezhong Zhang;Hetty N. Wong;Benbo Song;Corey N. Miller

  • The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

    Kezhong Zhang;Kezhong Zhang;Shiyu Wang;Jyoti Malhotra;Justin R Hassler

  • ER Stress Controls Iron Metabolism Through Induction of Hepcidin

    Chiara Vecchi;Giuliana Montosi;Kezhong Zhang;Igor Lamberti

  • The unfolded protein response--a stress signaling pathway of the endoplasmic reticulum.

    Xiaohua Shen;Kezhong Zhang;Randal J. Kaufman

  • Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease

    Aditya Dandekar;Roberto Mendez;Kezhong Zhang

  • Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

    Ze Zheng;Xiaohua Xu;Xuebao Zhang;Aixia Wang

  • ER stress signaling by regulated splicing: IRE1/HAC1/XBP1.

    Sung Hoon Back;Martin Schröder;Kyungho Lee;Kezhong Zhang

  • TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

    Gazi S. Hossain;Johannes V. van Thienen;Geoff H. Werstuck;Ji Zhou

  • Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues

    Suzette Laing;Guohui Wang;Tamara Briazova;Chunbin Zhang

  • Regulation of apoptosis by the unfolded protein response.

    Andrew Fribley;Kezhong Zhang;Kezhong Zhang;Randal J. Kaufman

  • Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

    Quan Qiu;Ze Zheng;Lin Chang;Yuan Si Zhao

  • Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models.

    Ze Zheng;Xuebao Zhang;Jiemei Wang;Aditya Dandekar

  • Endoplasmic reticulum stress response in cancer: Molecular mechanism and therapeutic potential

    Guohui Wang;Zeng Quan Yang;Kezhong Zhang

Frequent Co-Authors

Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Deyu Fang
Deyu Fang Northwestern University
Sanjay Rajagopalan
Sanjay Rajagopalan Case Western Reserve University
Li Wang
Li Wang Yale University
Lawrence I. Grossman
Lawrence I. Grossman Wayne State University
Donna D. Zhang
Donna D. Zhang University of Arizona
Henry H.Q. Heng
Henry H.Q. Heng Wayne State University
Jiandie D. Lin
Jiandie D. Lin University of Michigan–Ann Arbor
Y. Eugene Chen
Y. Eugene Chen University of Michigan–Ann Arbor
Maik Hüttemann
Maik Hüttemann Wayne State University

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