What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Enzyme
His primary areas of investigation include Internal medicine, Endocrinology, Genetics, Cell biology and Peroxisome proliferator-activated receptor.
In his research, Proinflammatory cytokine and Vascular smooth muscle is intimately related to Macrophage, which falls under the overarching field of Internal medicine.
His Endocrinology study frequently involves adjacent topics like Cell signaling.
In his study, CRISPR interference, CRISPR, Enhancer, Effector and Transcription activator-like effector nuclease is strongly linked to Computational biology, which falls under the umbrella field of Genetics.
His Cell biology research incorporates elements of Tube formation, microRNA, Angiogenesis and Cellular differentiation.
His Peroxisome proliferator-activated receptor study integrates concerns from other disciplines, such as Peroxisome, Rosiglitazone, Insulin and Homeostasis.
His most cited work include:
- Exome-wide association study of plasma lipids in > 300,000 individuals (265 citations)
- RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency. (252 citations)
- The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis (235 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Internal medicine, Endocrinology, Cell biology, Inflammation and Peroxisome proliferator-activated receptor.
His work deals with themes such as Wild type and Cardiology, which intersect with Internal medicine.
His study on Endocrinology is mostly dedicated to connecting different topics, such as Downregulation and upregulation.
He has included themes like Embryonic stem cell, Vascular smooth muscle and Cellular differentiation in his Cell biology study.
The concepts of his Inflammation study are interwoven with issues in Endothelial stem cell, Cancer research, Cytokine, Transcription factor and Macrophage.
His studies in Peroxisome proliferator-activated receptor integrate themes in fields like Peroxisome and Rosiglitazone.
He most often published in these fields:
- Internal medicine (31.63%)
- Endocrinology (27.44%)
- Cell biology (22.33%)
What were the highlights of his more recent work (between 2019-2021)?
- Internal medicine (31.63%)
- Endocrinology (27.44%)
- Cholesterol (11.16%)
In recent papers he was focusing on the following fields of study:
Y. Eugene Chen mainly investigates Internal medicine, Endocrinology, Cholesterol, Cancer research and Computational biology.
The various areas that Y. Eugene Chen examines in his Internal medicine study include Minor allele frequency and Cardiology.
His Endocrinology study frequently intersects with other fields, such as Nonalcoholic fatty liver disease.
His research in Cancer research intersects with topics in Inflammation, Transcription factor, Telomerase, Telomere and Macrophage.
His study looks at the intersection of Transcription factor and topics like IRS1 with TFEB and Cell biology.
Y. Eugene Chen combines subjects such as Downregulation and upregulation and Metabolism with his study of Cell biology.
Between 2019 and 2021, his most popular works were:
- Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping. (21 citations)
- TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice. (16 citations)
- Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB. (11 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
His scientific interests lie mostly in Internal medicine, Vascular smooth muscle, Fatty liver, Adipose tissue and Pathology.
The Internal medicine study combines topics in areas such as Phenotype and Endocrinology.
His biological study spans a wide range of topics, including Thoracic aortic aneurysm, Cell, Calponin, Autophagy and Pharmacological therapy.
His biological study deals with issues like Bioinformatics, which deal with fields such as Type 2 diabetes.
His work investigates the relationship between Adipose tissue and topics such as Mendelian randomization that intersect with problems in Insulin resistance.
His Pathology research is multidisciplinary, relying on both Lineage specific, Myocardin, In vitro and Neural crest.
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