2026 Y. Eugene Chen: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	77	4848	4472	2333	2096	254	18536

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

4848

4472

2333

2096

254

18536

Biology and Biochemistry

D-Index

Citations

18536

World Ranking

4848

National Ranking

2333

Overview

Y. Eugene Chen is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans broad areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on subfields including molecular biology, pulmonary and respiratory medicine, surgery, genetics, and cancer research.

The scientist's work covers several main research topics such as aortic aneurysm repair treatments, CRISPR and genetic engineering, aortic disease and treatment approaches, connective tissue disorders research, atherosclerosis and cardiovascular diseases, microRNA in disease regulation, and liver disease diagnosis and treatment.

Chen has contributed to numerous publications in prominent scientific venues. Frequent publication outlets include:

Arteriosclerosis Thrombosis and Vascular Biology
JCI Insight
bioRxiv (Cold Spring Harbor Laboratory)
Zenodo (CERN European Organization for Nuclear Research)
Science Translational Medicine

Notable recent papers associated with Chen, with publication year and venue, include:

"Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping" (2020, Journal of Hepatology)
"Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome" (2020, Science Translational Medicine)
"Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta" (2020, Cardiovascular Research)
"A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study" (2022, European Heart Journal)
"Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb" (2020, Stem Cell Research & Therapy)

The scientist frequently collaborates with several coauthors who have contributed to multiple projects together. Frequent coauthors include:

Jifeng Zhang
Yanhong Guo
Minerva T. Garcia-Barrio
Haocheng Lu
Lin Chang

Best Publications

Exome-wide association study of plasma lipids in > 300,000 individuals

Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

591
Citations
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.

Jun Song;Dongshan Yang;Jie Xu;Tianqing Zhu

448
Citations
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

Kezhong Zhang;Kezhong Zhang;Shiyu Wang;Jyoti Malhotra;Justin R Hassler

401
Citations
Loss of Perivascular Adipose Tissue on Peroxisome Proliferator–Activated Receptor-γ Deletion in Smooth Muscle Cells Impairs Intravascular Thermoregulation and Enhances Atherosclerosis

Lin Chang;Luis Villacorta;Rongxia Li;Milton Hamblin

383
Citations
miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia

Ke Jie Yin;Zhen Deng;Huarong Huang;Milton Hamblin

363
Citations
Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine.

Jianglin Fan;Shuji Kitajima;Teruo Watanabe;Jie Xu

337
Citations
High-Density Lipoproteins: Nature’s Multifunctional Nanoparticles

Rui Kuai;Dan Li;Y. Eugene Chen;James J. Moon

325
Citations
Perivascular Adipose Tissue in Vascular Function and Disease: A Review of Current Research and Animal Models

Nicholas K. Brown;Zhou Zhou;Jifeng Zhang;Rong Zeng

316
Citations
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

Oddgeir L Holmen;He-Ming Zhang;Yanbo Fan;Daniel H. Hovelson

307
Citations
PPARs and the cardiovascular system.

Milton Hamblin;Lin Chang;Yanbo Fan;Jifeng Zhang

260
Citations
Molecular recognition of nitrated fatty acids by PPAR gamma.

Yong Li;Yong Li;Jifeng Zhang;Francisco J Schopfer;Dariusz Martynowski

249
Citations
Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.

Ke Jie Yin;Zhen Deng;Zhen Deng;Milton Hamblin;Yi Xiang

239
Citations
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

Leslie A Lange;Youna Hu;He Zhang;Chenyi Xue

238
Citations
Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects.

Xiaojin Zhang;Yan Li;Yan Li;Y. Eugene Chen;Jihua Chen

228
Citations
Porous nanofibrous PLLA scaffolds for vascular tissue engineering

Jiang Hu;Xuan Sun;Xuan Sun;Haiyun Ma;Changqing Xie

227
Citations
Adipose-Derived Stem Cells Induce Angiogenesis via Microvesicle Transport of miRNA-31

Ting Kang;Tia M. Jones;Clayton Naddell;Methode Bacanamwo

217
Citations
Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

Dongshan Yang;Huaqiang Yang;Wei Li;Bentian Zhao

209
Citations
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome

Oren Rom;Yuhao Liu;Zhipeng Liu;Ying Zhao

194
Citations
Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids SELECTIVE LIGAND ACTIVITY AND ANTI-DIABETIC SIGNALING ACTIONS

Francisco J. Schopfer;Marsha P. Cole;Alison L. Groeger;Chen Shan Chen

194
Citations
Effective gene targeting in rabbits using RNA-guided Cas9 nucleases

Dongshan Yang;Jie Xu;Tianqing Zhu;Jianglin Fan

193
Citations