D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 50 Citations 10,532 154 World Ranking 3687 National Ranking 85

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

His main research concerns Cell biology, Molecular biology, Embryo, Genetics and Somatic cell. The various areas that he examines in his Cell biology study include Huntington's disease, Huntingtin Protein, Huntingtin and Neurodegeneration. Liangxue Lai usually deals with Molecular biology and limits it to topics linked to Mutant and Cas9 and CRISPR.

Liangxue Lai has researched Embryo in several fields, including Cell culture, Embryonic stem cell and Transgene. Liangxue Lai interconnects Reprogramming, Green fluorescent protein, Stem cell, Cloning and Somatic cell nuclear transfer in the investigation of issues within Somatic cell. His studies deal with areas such as Andrology and Pronucleus as well as Blastocyst.

His most cited work include:

  • Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. (1157 citations)
  • A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts (892 citations)
  • Production of α-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations (392 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Molecular biology, Cell biology, Gene, Genetics and Somatic cell nuclear transfer. His studies in Molecular biology integrate themes in fields like Gene expression, CRISPR, Somatic cell, Mutation and Blastocyst. His Mutation research incorporates elements of Phenotype and Mutant.

His Cell biology study also includes

  • Induced pluripotent stem cell that connect with fields like Reprogramming,
  • In vitro most often made with reference to Cell culture. His work on Genetics is being expanded to include thematically relevant topics such as Tyrosinase. His Somatic cell nuclear transfer study integrates concerns from other disciplines, such as Andrology and Methylation.

He most often published in these fields:

  • Molecular biology (39.32%)
  • Cell biology (33.76%)
  • Gene (30.77%)

What were the highlights of his more recent work (between 2016-2021)?

  • CRISPR (26.07%)
  • Gene (30.77%)
  • Cell biology (33.76%)

In recent papers he was focusing on the following fields of study:

CRISPR, Gene, Cell biology, Computational biology and Cas9 are his primary areas of study. His study in CRISPR is interdisciplinary in nature, drawing from both Classical swine fever, Transgene, Virology, Molecular biology and Gene Knockout Techniques. His research in Molecular biology intersects with topics in Human embryonic stem cell line, Mutation, Apoptosis, Gene knockout and Wild type.

Gene is a subfield of Genetics that Liangxue Lai tackles. Liangxue Lai specializes in Cell biology, namely Somatic cell nuclear transfer. His work on Guide RNA as part of general Cas9 study is frequently linked to Animal welfare, therefore connecting diverse disciplines of science.

Between 2016 and 2021, his most popular works were:

  • Establishment of porcine and human expanded potential stem cells (98 citations)
  • A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. (93 citations)
  • A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. (93 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

Liangxue Lai mainly focuses on Cas9, Cell biology, CRISPR, Computational biology and Gene. Liangxue Lai combines subjects such as Genetically modified organism, Virus, Viral replication, Virology and RNA interference with his study of Cas9. His Cell biology research is multidisciplinary, incorporating elements of Germline, Huntingtin Protein, Huntington's disease and Pathogenesis.

His research on CRISPR concerns the broader Genetics. He focuses mostly in the field of Computational biology, narrowing it down to matters related to Genome editing and, in some cases, Transcription. His study in Ectopic expression, Derepression, Gene expression, Somatic cell nuclear transfer and Transcriptome falls within the category of Gene.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

Liangxue Lai;Donna Kolber-Simonds;Kwang-Wook Park;Hee-Tae Cheong.
Science (2002)

1736 Citations

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

Ronghui Li;Jialiang Liang;Su Ni;Ting Zhou.
Cell Stem Cell (2010)

1165 Citations

Generation of cloned transgenic pigs rich in omega-3 fatty acids.

Liangxue Lai;Jing X Kang;Rongfeng Li;Jingdong Wang.
Nature Biotechnology (2006)

516 Citations

Production of α-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations

Donna Kolber-Simonds;Liangxue Lai;Steven R. Watt;Maria Denaro.
Proceedings of the National Academy of Sciences of the United States of America (2004)

499 Citations

Generation of Induced Pluripotent Stem Cell Lines from Tibetan Miniature Pig

Miguel Angel Esteban;Jianyong Xu;Jiayin Yang;Meixiu Peng.
Journal of Biological Chemistry (2009)

492 Citations

Translocation of active mitochondria during pig oocyte maturation, fertilization and early embryo development in vitro

QY Sun;GM Wu;L Lai;KW Park.
Reproduction (2001)

336 Citations

MicroRNA cluster 302-367 enhances somatic cell reprogramming by accelerating a mesenchymal-to-epithelial transition.

Baojian Liao;Xichen Bao;Xichen Bao;Longqi Liu;Shipeng Feng.
Journal of Biological Chemistry (2011)

293 Citations

Production of nuclear transfer-derived swine that express the enhanced green fluorescent protein.

Kwang-Wook Park;Hee-Tae Cheong;Liangxue Lai;Gi-Sun Im.
Animal Biotechnology (2001)

268 Citations

Transgenic swine for biomedicine and agriculture

R.S Prather;R.J Hawley;D.B Carter;L Lai.
Theriogenology (2003)

259 Citations

Transgenic pig expressing the enhanced green fluorescent protein produced by nuclear transfer using colchicine‐treated fibroblasts as donor cells

Liangxue Lai;Kwang‐Wook Park;Hee‐Tae Cheong;Hee‐Tae Cheong;Birgit Kühholzer.
Molecular Reproduction and Development (2002)

236 Citations

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