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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Molecular Biology

D-Index
91
Citations
26147
World Ranking
727
National Ranking
17

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award
  • 2016 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Laszlo Tora is affiliated with the Institute of Genetics and Molecular and Cellular Biology in France. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as reflected by the majority of their publications.

Their scientific work covers various subfields including molecular biology, oncology, genetics, cancer research, and biomedical engineering. Major topics addressed in their research include genomics and chromatin dynamics, RNA research and splicing, protein degradation and inhibitors, RNA and protein synthesis mechanisms, CRISPR and genetic engineering, ubiquitin and proteasome pathways, and histone deacetylase inhibitors research.

Laszlo Tora has published extensively, especially in venues such as bioRxiv (Cold Spring Harbor Laboratory), where they have 15 publications. Other frequent publication outlets include Cell Reports, Science Advances, Nucleic Acids Research, and Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature.

Significant recent papers authored or co-authored by Laszlo Tora include:

  • TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage (2020, Nature Communications)
  • What do the structures of GCN5-containing complexes teach us about their function? (2020, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms)
  • Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID (2023, Nature Structural & Molecular Biology)
  • The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms (2021, Cell Reports)
  • Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription (2021, Cell Death and Differentiation)

They have collaborated frequently with several co-authors, including Stéphane D. Vincent, Didier Devys, Elisabeth Scheer, Luc Négroni, and Andrea Bernardini, indicating ongoing research partnerships within their field.

Laszlo Tora has been recognized by membership in prestigious organizations such as the Academia Europaea since 2016 and the European Molecular Biology Organization (EMBO).

Best Publications

  • Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

    P Kastner;A Krust;B Turcotte;U Stropp

  • Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

    Yvon Trottier;Yves Lutz;Giovanni Stevanin;Georges Imbert

  • The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

    B. Le Douarin;C. Zechel;J.M. Garnier;Y. Lutz

  • Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

    Anne Helmrich;Monica Ballarino;Laszlo Tora

  • H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

    Krishanpal Karmodiya;Arnaud R Krebs;Arnaud R Krebs;Mustapha Oulad-Abdelghani;Hiroshi Kimura

  • Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.

    K Gradin;J McGuire;R H Wenger;I Kvietikova

  • Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

    Xavier Jacq;Xavier Jacq;Christel Brou;Christel Brou;Yves Lutz;Yves Lutz;Irwin Davidson;Irwin Davidson

  • The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.

    L. Tora;A. Mullick;D. Metzger;M. Ponglikitmongkol

  • The N-terminal region of the chicken progesterone receptor specifies target gene activation.

    Laszlo Tora;Hinrich Gronemeyer;Bernard Turcotte;Marie-Pierre Gaub

  • Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.

    Z Nagy;L Tora

  • seqMINER: an integrated ChIP-seq data interpretation platform

    Tao Ye;Arnaud R Krebs;Mohamed Amin Choukrallah;Céline Keime

  • Distinct classes of transcriptional activating domains function by different mechanisms.

    Diane Tasset;Diane Tasset;Laszlo Tora;Laszlo Tora;Catherine Fromental;Catherine Fromental;Elisabeth Scheer;Elisabeth Scheer

  • hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

    A. Bertolotti;Y. Lutz;D. J. Heard;P. Chambon

  • A TFTC/STAGA Module Mediates Histone H2A and H2B Deubiquitination, Coactivates Nuclear Receptors, and Counteracts Heterochromatin Silencing

    Yue Zhao;Guillaume Lang;Saya Ito;Jacques Bonnet

  • Transcription factor TFIID recruits factor CPSF for formation of 3′ end of mRNA

    Jean-Christophe Dantonel;Kanneganti G. K. Murthy;James L. Manley;Laszlo Tora

  • EWS, but Not EWS-FLI-1, Is Associated with Both TFIID and RNA Polymerase II: Interactions between Two Members of the TET Family, EWS and hTAFII68, and Subunits of TFIID and RNA Polymerase II Complexes

    Anne Bertolotti;Thomas Melot;Joël Acker;Marc Vigneron

  • A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically

    Shigeaki Kato;Laszlo Tora;Jun Yamauchi;Shoichi Masushige

  • Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3

    Angèle Santenard;Céline Ziegler-Birling;Marc Koch;Làszlò Tora

  • Function of TAF II -containing complex without TBP in transcription by RNA polymerase II

    Elzbieta Wieczorek;Elzbieta Wieczorek;Marjorie Brand;Xavier Jacq;Xavier Jacq;László Tora

  • Transcription-replication encounters, consequences and genomic instability

    Anne Helmrich;Monica Ballarino;Monica Ballarino;Evgeny Nudler;Laszlo Tora

Frequent Co-Authors

Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Irwin Davidson
Irwin Davidson Institute of Genetics and Molecular and Cellular Biology
Tao Ye
Tao Ye Pennsylvania State University
Imre Berger
Imre Berger University of Bristol
Patrick Schultz
Patrick Schultz Institute of Genetics and Molecular and Cellular Biology
Hinrich Gronemeyer
Hinrich Gronemeyer Institute of Genetics and Molecular and Cellular Biology
Shigeaki Kato
Shigeaki Kato University of Tokyo
H. Th. Marc Timmers
H. Th. Marc Timmers University of Freiburg
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Boris Lenhard
Boris Lenhard Imperial College London

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