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Best Scientists
2025
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Molecular Biology
USA
2025

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Best Scientists

D-Index
185
Citations
125674
World Ranking
514
National Ranking
333

Molecular Biology

D-Index
178
Citations
106080
World Ranking
39
National Ranking
25

Medicine

D-Index
187
Citations
128824
World Ranking
283
National Ranking
184

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2018 - Fellow, National Academy of Inventors
  • 2007 - US President's National Medal of Science "For his pioneering work on the molecular mechanisms of steroid hormone action and hormone receptors and coactivators, which has had a profound impact on our knowledge of steroid hormones in normal development and in diseases, including cancer.", Presented by President George W. Bush in the East Room of the White House on September 29, 2008.
  • 1995 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1992 - Member of the National Academy of Sciences

Overview

Bert W. O'Malley is affiliated with Baylor College of Medicine in the United States. Their research work spans multiple fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, O'Malley has contributed extensively to subfields such as molecular biology, surgery, oncology, genetics, and otorhinolaryngology.

Their research topics cover a range of scientific areas including:

  • Estrogen and related hormone effects
  • Head and neck cancer studies
  • Head and neck surgical oncology
  • Salivary gland tumors diagnosis and treatment
  • Cancer diagnosis and treatment
  • Reproductive system and pregnancy
  • Oral and maxillofacial pathology

O'Malley's recent published papers illustrate a strong focus on molecular mechanisms, cancer treatment, and surgical oncology:

  • Mechanisms of enhancer action: the known and the unknown, 2021, Genome Biology
  • Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes, 2020, Molecular Cell
  • Drug Combination in Cancer Treatment-From Cocktails to Conjugated Combinations, 2021, Cancers
  • Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment, 2021, Nature Communications
  • Transoral robotic surgical resection followed by randomization to low- or standard-dose IMRT in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN Cancer Research Group (E3311), 2020, Journal of Clinical Oncology

Frequent co-authors of O'Malley include:

  • David M. Lonard
  • Gregory S. Weinstein
  • Jason G. Newman
  • Robert M. Brody
  • Karthik Rajasekaran

Their work is commonly published in several well-known scientific venues, such as:

  • Head & Neck
  • Journal of Clinical Oncology
  • The Laryngoscope
  • Journal of Neurological Surgery Part B Skull Base
  • Nature Communications

Throughout their career, O'Malley has received recognition that includes multiple awards:

  • Fellow, National Academy of Inventors, 2018
  • US President's National Medal of Science, 2007, awarded for pioneering work on the molecular mechanisms of steroid hormone action and hormone receptors and coactivators
  • Fellow of the American Association for the Advancement of Science (AAAS), 1995
  • Member of the National Academy of Sciences, 1992

Best Publications

  • MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

    Ming-Jer Tsai;Bert W. O'Malley

  • Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

    Sergio A. Oñate;Sophia Y. Tsai;Ming-Jer Tsai;Bert W. O'Malley

  • Steroid receptor coactivator-1 is a histone acetyltransferase

    T E Spencer;G Jenster;G Jenster;M M Burcin;C D Allis

  • Female steroid hormones and target cell nuclei.

    Bert W. O'Malley;Anthony R. Means

  • A unified nomenclature system for the nuclear receptor superfamily

    J. Auwerx;E. Baulieu;M. Beato;M. Becker-Andre

  • Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells

    Barry S. Komm;Christopher M. Terpening;David J. Benz;Kimberlie A. Graeme

  • A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex.

    Rainer B Lanz;Neil J McKenna;Sergio A Onate;Urs Albrecht

  • Transoral robotic surgery (TORS) for base of tongue neoplasms.

    Bert W. O'Malley;Gregory S. Weinstein;Wendy Snyder;Neil G. Hockstein

  • Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene

    Jianming Xu;Yuhong Qiu;Francesco J. DeMayo;Sophia Y. Tsai

  • Transoral robotic surgery: radical tonsillectomy.

    Gregory S. Weinstein;Bert W. O’Malley;Wendy Snyder;Eric Sherman

  • Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

    John A. Katzenellenbogen;Bert W. O'Malley;Benita S. Katzenellenbogen

  • Dopaminergic and ligand-independent activation of steroid hormone receptors.

    Ronan F. Power;Shaila K. Mani;Juan Codina;Orla M. Conneely

  • A regulatory system for use in gene transfer

    Yaolin Wang;Bert W. O'Malley;Sophia Y. Tsai

  • Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

    Sophia Y. Tsai;Jan Carlstedt-Duke;Nancy L. Weigel;Karin Dahlman

  • The steroid receptor superfamily: more excitement predicted for the future.

    Bert O'Malley

  • COUP transcription factor is a member of the steroid receptor superfamily.

    Lee-Ho Wang;Sophia Y. Tsai;Richard G. Cook;Wanda G. Beattie

  • A paracrine role for the epithelial progesterone receptor in mammary gland development

    Cathrin Brisken;Sissela Park;Tibor Vass;John P. Lydon

  • Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

    Donald P. Mcdonnell;David J. Mangelsdorf;J. Wesley Pike;Mark R. Haussler

  • Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases

    R. L. Robker;D. L. Russell;L. L. Espey;J. P. Lydon

  • Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.

    Neil J. McKenna;Jianming Xu;Zafar Nawaz;Sophia Y. Tsai

Frequent Co-Authors

Ming-Jer Tsai
Ming-Jer Tsai Baylor College of Medicine
Sophia Y. Tsai
Sophia Y. Tsai Baylor College of Medicine
William T. Schrader
William T. Schrader Baylor College of Medicine
Jianming Xu
Jianming Xu Zhejiang University
John P. Lydon
John P. Lydon Baylor College of Medicine
Orla M. Conneely
Orla M. Conneely Baylor College of Medicine
Francesco J. DeMayo
Francesco J. DeMayo National Institutes of Health
Savio L. C. Woo
Savio L. C. Woo Icahn School of Medicine at Mount Sinai
Anthony R. Means
Anthony R. Means Baylor College of Medicine
Nancy L. Weigel
Nancy L. Weigel Baylor College of Medicine

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