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Medicine

D-Index
119
Citations
52483
World Ranking
3898
National Ranking
2131

Overview

Chawnshang Chang is affiliated with the University of Rochester Medical Center in the United States. The primary fields of study covered by their research include Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, their work focuses on subfields such as Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Oncology, and Immunology.

The research topics addressed by Chang include Prostate Cancer Treatment and Research, Cancer-related molecular mechanisms research, Circular RNAs in diseases, MicroRNA in disease regulation, Cancer, Lipids, and Metabolism, Cancer, Hypoxia, and Metabolism, and Ubiquitin and proteasome pathways.

Chang has contributed extensively to scientific literature with notable publications including:

  • Androgen receptor-regulated circ FNTA activates KRAS signaling to promote bladder cancer invasion (2020, EMBO Reports)
  • The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer (2020, Nature Communications)
  • The miR-92a-2-5p in exosomes from macrophages increases liver cancer cells invasion via altering the AR/PHLPP/p-AKT/β-catenin signaling (2020, Cell Death and Differentiation)
  • Estrogen receptor α promotes lung cancer cell invasion via increase of and cross-talk with infiltrated macrophages through the CCL2/CCR2/MMP9 and CXCL12/CXCR4 signaling pathways (2020, Molecular Oncology)
  • Estrogen and G protein-coupled estrogen receptor accelerate the progression of benign prostatic hyperplasia by inducing prostatic fibrosis (2022, Cell Death and Disease)

Frequent coauthors who have collaborated extensively with Chang include:

  • Shuyuan Yeh
  • Chi-Ping Huang
  • Yin Sun
  • Bosen You
  • Fu-Ju Chou

Many of Chang's works are published in prominent journals such as:

  • The Journal of Urology
  • Cell Death and Disease
  • The Prostate
  • Oncogene
  • Cancer Letters

Best Publications

  • Androgen Receptor in Prostate Cancer

    Cynthia A. Heinlein;Chawnshang Chang

  • Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study

    R B Simerly;C Chang;M Muramatsu;L W Swanson

  • Androgen Receptor (AR) Coregulators: An Overview

    Cynthia A. Heinlein;Chawnshang Chang

  • Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

    Chawnshang S. Chang;John Kokontis;Shutsung Liao

  • Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

    Shuyuan Yeh;Chawnshang Chang

  • The Roles of Androgen Receptors and Androgen- Binding Proteins in Nongenomic Androgen Actions

    Cynthia A. Heinlein;Chawnshang Chang

  • Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.

    Chawnshang Chang;John Kokontis;Shutsung Liao

  • From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

    Shuyuan Yeh;Hui Kuan Lin;Hong Yo Kang;Tin Htwe Thin

  • Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues

    Shuyuan Yeh;Meng Yin Tsai;Meng Yin Tsai;Qingquan Xu;Xiao Min Mu

  • Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

    Chawnshang Chang;Yen-Ta Chen;Yen-Ta Chen;Shauh-Der Yeh;Qingquan Xu

  • Induction of the TRPM-2 gene in cells undergoing programmed death.

    R. Buttyan;C. A. Olsson;J. Pintar;Chawnshang Chang

  • Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice

    Ruey Sheng Wang;Shuyuan Yeh;Chii Ruey Tzeng;Chii Ruey Tzeng;Chawnshang Chang

  • Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

    Hui Kuan Lin;Liang Wang;Yueh Chiang Hu;Saleh Altuwaijri

  • Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

    Hui-Kuan Lin;Shuyuan Yeh;Hong-Yo Kang;Chawnshang Chang

  • Promotion of Bladder Cancer Development and Progression by Androgen Receptor Signals

    Hiroshi Miyamoto;Zhiming Yang;Yei Tsung Chen;Hitoshi Ishiguro

  • Androgen deprivation therapy for prostate cancer: current status and future prospects.

    Hiroshi Miyamoto;Edward M. Messing;Chawnshang Chang;Chawnshang Chang

  • Androgen receptor: an overview.

    Chawnshang Chang;Alan Saltzman;Shuyuan Yeh;Winjing Young

  • Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: a population-based case-control study in China.

    Ann W. Hsing;Yu-Tang Gao;Guan Wu;Xin Wang

  • Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.

    Hironori Ohtsu;Zhiyan Xiao;Junko Ishida;Masahiro Nagai

  • Androgen receptor is a tumor suppressor and proliferator in prostate cancer

    Yuanjie Niu;Saleh Altuwaijri;Kuo-Pao Lai;Chun-Te Wu

Frequent Co-Authors

Shuyuan Yeh
Shuyuan Yeh University of Rochester Medical Center
Edward M. Messing
Edward M. Messing University of Rochester Medical Center
Hui Kuan Lin
Hui Kuan Lin Wake Forest University
Shutsung Liao
Shutsung Liao University of Chicago
Henry A. Lardy
Henry A. Lardy University of Wisconsin–Madison
Kuo Hsiung Lee
Kuo Hsiung Lee University of Minnesota
David A. Bushinsky
David A. Bushinsky University of Rochester
Ann W. Hsing
Ann W. Hsing Stanford University
Hideji Itokawa
Hideji Itokawa University of Tokyo
Eugene B. Chang
Eugene B. Chang University of Chicago

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