World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
21203
World Ranking
5557
National Ranking
2639

Overview

Hui Kuan Lin is affiliated with Wake Forest University in the United States and conducts research primarily in the fields of biochemistry, genetics, molecular biology, medicine, immunology, and microbiology.

The scientist's work spans several subfields, including molecular biology, oncology, and immunology. Their research topics focus notably on melanoma and MAPK pathways, cancer-related molecular pathways, and interferon and immune responses.

Recent publications include the 2025 paper titled "EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis", published in the Journal of Clinical Investigation. This paper explores molecular mechanisms involved in tumorigenesis.

Frequent co-authors collaborating with Hui Kuan Lin include:

  • Haizhong Feng
  • Giselle Y. López
  • Chung Kwon Kim
  • Angel A. Alvarez
  • Christopher G. Duncan

The scientist's work has appeared in the Journal of Clinical Investigation, which is noted as a main publication venue with at least one publication.

Best Publications

  • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

    Zhenbang Chen;Lloyd C. Trotman;David Shaffer;Hui Kuan Lin

  • BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

    Nicholas J. Donato;Ji Yuan Wu;Jonathan Stapley;Gary Gallick

  • From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

    Shuyuan Yeh;Hui Kuan Lin;Hong Yo Kang;Tin Htwe Thin

  • The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

    Wei Lei Yang;Jing Wang;Chia Hsin Chan;Szu Wei Lee;Szu Wei Lee

  • The Mechanisms of PML-Nuclear Body Formation

    Tian Huai Shen;Hui Kuan Lin;Pier Paolo Scaglioni;Thomas M. Yung

  • Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

    Hui Kuan Lin;Liang Wang;Yueh Chiang Hu;Saleh Altuwaijri

  • Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

    Hui-Kuan Lin;Shuyuan Yeh;Hong-Yo Kang;Chawnshang Chang

  • Skp2 targeting suppresses tumorigenesis by Arf-p53- independent cellular senescence

    Hui Kuan Lin;Zhenbang Chen;Zhenbang Chen;Zhenbang Chen;Guocan Wang;Caterina Nardella;Caterina Nardella

  • Circular RNAs in cancer: novel insights into origins, properties, functions and implications.

    Jingqiu Li;Jie Yang;Ping Zhou;Yanping Le

  • LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

    Dahu Chen;Yutong Sun;Yongkun Wei;Peijing Zhang

  • PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

    Carlotta Giorgi;Keisuke Ito;Keisuke Ito;Hui Kuan Lin;Clara Santangelo

  • Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression

    Chia Hsin Chan;John Kenneth Morrow;John Kenneth Morrow;Chien Feng Li;Yuan Gao;Yuan Gao

  • Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS.

    Weina Zhang;Guihua Wang;Zhi-Gang Xu;Haiqing Tu

  • The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

    Chia Hsin Chan;Chien Feng Li;Chien Feng Li;Wei Lei Yang;Wei Lei Yang;Yuan Gao;Yuan Gao

  • Cytoplasmic PML function in TGF-β signalling

    Hui Kuan Lin;Stephan Bergmann;Pler Paolo Pandolfi

  • Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

    Hui Kuan Lin;Hui Kuan Lin;Guocan Wang;Guocan Wang;Zhenbang Chen;Zhenbang Chen;Zhenbang Chen;Julie Teruya-Feldstein

  • LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress.

    Xiaowen Liu;Zhen Dong Xiao;Leng Han;Jiexin Zhang

  • Janus Kinase 2: A Critical Target in Chronic Myelogenous Leukemia

    Ajoy K. Samanta;Hui Lin;Tong Sun;Hagop M Kantarjian

  • Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis

    Chia Hsin Chan;Szu Wei Lee;Szu Wei Lee;Chien Feng Li;Jing Wang

  • Inhibition of Lipocalin 2 Impairs Breast Tumorigenesis and Metastasis

    Xiaohong Leng;Tian Ding;Hui Lin;Yan Wang

Frequent Co-Authors

Mien Chie Hung
Mien Chie Hung China Medical University
Chawnshang Chang
Chawnshang Chang University of Rochester Medical Center
Pier Paolo Pandolfi
Pier Paolo Pandolfi Beth Israel Deaconess Medical Center
Jing Wang
Jing Wang The University of Texas MD Anderson Cancer Center
Shuyuan Yeh
Shuyuan Yeh University of Rochester Medical Center
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Chang Hai Tsai
Chang Hai Tsai Asian University
Julie Teruya-Feldstein
Julie Teruya-Feldstein Icahn School of Medicine at Mount Sinai
Yongkun Wei
Yongkun Wei The University of Texas MD Anderson Cancer Center
Fuu Jen Tsai
Fuu Jen Tsai China Medical University

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