World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
60
Citations
13896
World Ranking
3150
National Ranking
1375

Overview

Jonathan Schug is affiliated with the University of Pennsylvania in the United States. Their research spans multiple disciplines, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. They have contributed extensively to the fields of Surgery, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Epidemiology.

Their work covers significant topics related to pancreatic function and diabetes, diabetes and associated disorders, diabetes management and research, single-cell and spatial transcriptomics, epigenetics and DNA methylation, cell image analysis techniques, and genetics and neurodevelopmental disorders.

Jonathan Schug has published research papers in various scientific venues, with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory), Diabetes, Nature Metabolism, Gastroenterology, and Molecular Metabolism.

Some of their recent notable papers include:

  • Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes, 2022, Nature Metabolism
  • Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D, 2020, Molecular Metabolism
  • Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry, 2021, Cell Reports
  • A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver, 2020, Proceedings of the National Academy of Sciences
  • Highly Multiplexed Image Analysis of Intestinal Tissue Sections in Patients With Inflammatory Bowel Disease, 2021, Gastroenterology

Jonathan Schug frequently collaborates with several co-authors, including Klaus H. Kaestner, Ali Naji, Deeksha Lahori, Daniel Traum, and Robert B. Faryabi. The most frequent co-author is Klaus H. Kaestner, with 22 joint works.

Best Publications

  • PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

    Martina I. Lefterova;Yong Zhang;David J. Steger;Michael Schupp

  • Promoter features related to tissue specificity as measured by Shannon entropy

    Jonathan Schug;Winfried-Paul Schuller;Claudia Kappen;J Michael Salbaum

  • PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data

    Amit Bahl;Brian P. Brunk;Jonathan Crabtree;Martin J. Fraunholz

  • Epigenomic plasticity enables human pancreatic α to β cell reprogramming

    Nuria C. Bramswig;Logan J. Everett;Jonathan Schug;Craig Dorrell

  • Using TESS to predict transcription factor binding sites in DNA sequence.

    Jonathan Schug

  • Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM)

    Gregory R. Grant;Michael H. Farkas;Angel D. Pizarro;Nicholas F. Lahens

  • Single-cell transcriptomics of the human endocrine pancreas

    Yue J. Wang;Jonathan Schug;Kyoung Jae Won;Chengyang Liu

  • Foxa1 and Foxa2 Are Essential for Sexual Dimorphism in Liver Cancer

    Zhaoyu Li;Geetu Tuteja;Jonathan Schug;Klaus H. Kaestner

  • Human islets contain four distinct subtypes of β cells.

    Craig Dorrell;Jonathan Schug;Pamela S. Canaday;Holger A. Russ

  • MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function.

    Lindsay B. McKenna;Jonathan Schug;Anastassios Vourekas;Jaime B. McKenna

  • Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.

    Vasumathi Kameswaran;Nuria C. Bramswig;Lindsay B. McKenna;Melinda Penn

  • K2/Kleisli and GUS: experiments in integrated access to genomic data sources

    S. B. Davidson;J. Crabtree;B. P. Brunk;J. Schug

  • Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

    Shannon E. Mullican;Christine A. Gaddis;Theresa Alenghat;Meera G. Nair

  • Glucocorticoid Receptor-Dependent Gene Regulatory Networks

    Phillip Phuc Le;Joshua R Friedman;Jonathan Schug;John E Brestelli

  • Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes

    Amanda M. Ackermann;Amanda M. Ackermann;Zhiping Wang;Jonathan Schug;Ali Naji

  • Propagation of adipogenic signals through an epigenomic transition state

    David J. Steger;Gregory R. Grant;Michael Schupp;Takuya Tomaru

  • Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

    Hongfang Wang;James Zou;Bo Zhao;Eric Johannsen

  • Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice

    Craig Dorrell;Laura Erker;Jonathan Schug;Janel L. Kopp

  • Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

    Ruiyu Xie;Logan J. Everett;Hee-Woong Lim;Nisha A. Patel

  • Transcriptomes of the major human pancreatic cell types

    C. Dorrell;J. Schug;C. F. Lin;P. S. Canaday

Frequent Co-Authors

Klaus H. Kaestner
Klaus H. Kaestner University of Pennsylvania
Christian J. Stoeckert
Christian J. Stoeckert University of Pennsylvania
Ali Naji
Ali Naji University of Pennsylvania
Markus Grompe
Markus Grompe Oregon Health & Science University
Jessica C. Kissinger
Jessica C. Kissinger University of Georgia
David S. Roos
David S. Roos University of Pennsylvania
Mitchell A. Lazar
Mitchell A. Lazar University of Pennsylvania
David J. Steger
David J. Steger University of Pennsylvania
Dirk Schübeler
Dirk Schübeler Friedrich Miescher Institute
Struan F.A. Grant
Struan F.A. Grant University of Pennsylvania

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in Genetics opens the door to several related online educational paths. Many students start their journey with foundational healthcare training or seek flexible study options to balance work and learning.

For those interested in healthcare administration, reviewing the best online medical billing and coding schools can provide a fast entry into the medical field. If your goal is to earn your degree more quickly, you might consider a fast track bachelor's degree online to accelerate your educational timeline.

Flexibility is essential for many students. Choosing a self paced online degree allows you to learn at your own speed, making it easier to balance education with life's other demands. Additionally, some schools make the application process easier and more affordable—explore online schools no application fee to reduce your upfront costs.

Whether your interest lies in genetics or a related healthcare field, these online options can help you start or advance your career, offering a range of flexibility and financial support.

Best Scientists Citing Jonathan Schug

Trending Scientists

Recently Published Articles