World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
17333
World Ranking
4876
National Ranking
47

Research.com Recognitions

  • 2014 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Susanne Mandrup is affiliated with the University of Southern Denmark in Denmark. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a focus on molecular biology, physiology, epidemiology, surgery, and genetics as subfields.

The scientist's main topics of work include adipose tissue and metabolism, genomics and chromatin dynamics, adipokines, inflammation, and metabolic diseases, single-cell and spatial transcriptomics, RNA research and splicing, liver disease diagnosis and treatment, and pancreatic function and diabetes.

Frequently, Susanne Mandrup has published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Nature Metabolism
  • Scientific Reports
  • Nature Communications

Their recent papers include:

  • Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution, 2020, Cell Metabolism
  • Adipose tissue at single-cell resolution, 2023, Cell Metabolism
  • An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors, 2021, Molecular Cell
  • Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis, 2021, Cell
  • Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities, 2021, Nature Metabolism

Susanne Mandrup collaborates with various researchers, including:

  • Ronni Nielsen
  • Jesper Grud Skat Madsen
  • Ann-Britt Marcher
  • Aleksander Krag
  • Lasse K. Markussen

The scientist has received recognition through memberships in scientific organizations such as:

  • Member of Academia Europaea (2014)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis.

    Ronni Nielsen;Thomas Askov Pedersen;Dik Hagenbeek;Panagiotis Moulos

  • PPARγ and the global map of adipogenesis and beyond

    Martina I. Lefterova;Anders K. Haakonsson;Mitchell A. Lazar;Susanne Mandrup

  • PPARs: Fatty acid sensors controlling metabolism

    Lars la Cour Poulsen;Majken Siersbæk;Susanne Mandrup

  • Adipogenesis: forces that tip the scales.

    Ormond A MacDougald;Susanne Mandrup

  • PPARγ in adipocyte differentiation and metabolism – Novel insights from genome-wide studies

    Rasmus Siersbæk;Ronni Nielsen;Susanne Mandrup

  • Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis

    Rasmus Siersbæk;Ronni Nielsen;Sam John;Myong-Hee Sung

  • ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION

    C S Hwang;T M Loftus;S Mandrup;M D Lane

  • Antiobesity mechanisms of action of conjugated linoleic acid.

    Arion Kennedy;Kristina Martinez;Soren Schmidt;Susanne Mandrup

  • Isomer-specific regulation of metabolism and PPARγ signaling by CLA in human preadipocytes

    J. Mark Brown;Maria Sandberg Boysen;Søren Skov Jensen;Ron F. Morrison

  • Transcriptional networks and chromatin remodeling controlling adipogenesis.

    Rasmus Siersbæk;Ronni Nielsen;Susanne Mandrup

  • The Orphan Nuclear Receptor Rev-Erbα Is a Peroxisome Proliferator-activated Receptor (PPAR) γ Target Gene and Promotes PPARγ-induced Adipocyte Differentiation

    Coralie Fontaine;Guillaume Dubois;Yannick Duguay;Torben Helledie

  • Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.

    Sheril Alex;Katja Lange;Tom Amolo;Jeffrey S Grinstead;Jeffrey S Grinstead

  • Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading.

    Maria Stahl Madsen;Rasmus Siersbæk;Michael Boergesen;Ronni Nielsen

  • Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

    Michael Boergesen;Thomas Åskov Pedersen;Barbara Gross;Simon J van Heeringen

  • Transcription Factor Cooperativity in Early Adipogenic Hotspots and Super-Enhancers

    Rasmus Siersbæk;Atefeh Rabiee;Ronni Nielsen;Simone Sidoli

  • Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha

    Cheng-Shine Hwang;S. Mandrup;O. A. Macdougald;D. E. Geiman

  • Patients With High Bone Mass Phenotype Exhibit Enhanced Osteoblast Differentiation and Inhibition of Adipogenesis of Human Mesenchymal Stem Cells

    Weimin Qiu;Tom E Andersen;Jens Bollerslev;Susanne Mandrup

  • Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution

    Anitta Kinga Sárvári;Elvira Laila Van Hauwaert;Lasse Kruse Markussen;Ellen Gammelmark

  • Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation

    Rasmus Siersbæk;Jesper Grud Skat Madsen;Biola Maria Javierre;Ronni Nielsen

  • Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men

    S. C. Jacobsen;C. Brons;C. Brons;J. Bork-Jensen;J. Bork-Jensen;R. Ribel-Madsen

Frequent Co-Authors

Karsten Kristiansen
Karsten Kristiansen University of Copenhagen
Nils J. Færgeman
Nils J. Færgeman University of Southern Denmark
Ole Nørregaard Jensen
Ole Nørregaard Jensen University of Southern Denmark
Pierre Maechler
Pierre Maechler University of Geneva
Satrajit Sinha
Satrajit Sinha University at Buffalo, State University of New York
Bruce E. Torbett
Bruce E. Torbett Seattle Children's Hospital
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Reiner A. Veitia
Reiner A. Veitia Université Paris Cité
Peggy J. Farnham
Peggy J. Farnham University of Southern California

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