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Microbiology

D-Index
57
Citations
12978
World Ranking
3554
National Ranking
1404

Overview

Bruce E. Torbett is affiliated with Seattle Children's Hospital in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these disciplines, their work focuses extensively on subfields such as Molecular Biology, Virology, Infectious Diseases, Ecology, and Epidemiology.

The scientist's research encompasses a variety of topics, including:

  • HIV Research and Treatment
  • Bacteriophages and microbial interactions
  • HIV/AIDS drug development and treatment
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Genomics and Phylogenetic Studies
  • RNA Research and Splicing

Their recent publications demonstrate a focus on viral mechanisms, RNA biology, and host-pathogen interactions. Notable papers include:

  • "Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase," 2020, Journal of Molecular Biology
  • "Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions," 2022, Cell Death and Disease
  • "Interactions of HIV-1 Capsid with Host Factors and Their Implications for Developing Novel Therapeutics," 2021, Viruses
  • "ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids," 2023, GigaScience
  • "MrHAMER yields highly accurate single molecule viral sequences enabling analysis of intra-host evolution," 2021, Nucleic Acids Research

Bruce E. Torbett frequently co-authors with a select group of collaborators, including:

  • Christian M. Gallardo
  • Andrew Routh
  • Mario P. Tschan
  • Magali Humbert
  • Stephanea Sotcheff

Their work has been published across various venues, with regular contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Journal of Molecular Biology
  • Biophysical Journal
  • Blood

Best Publications

  • Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

    Scott R. McKercher;Bruce E. Torbett;Karen L. Anderson;Gregory W. Henkel

  • Transduction of Human CD34+ Cells That Mediate Long-Term Engraftment of NOD/SCID Mice by HIV Vectors

    Hiroyuki Miyoshi;Kent A. Smith;Donald E. Mosier;Inder M. Verma

  • Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice.

    Luc J.W. van der Laan;Christopher Lockey;Bradley C. Griffeth;Francine S. Frasier

  • Patterns of cytokine gene expression by CD4+ T cells from young and old mice.

    M V Hobbs;W O Weigle;D J Noonan;B E Torbett

  • A new murine CD4+ T cell subset with an unrestricted cytokine profile.

    G S Firestein;W D Roeder;J A Laxer;K S Townsend

  • PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding

    Pu Zhang;Xiaobo Zhang;Atsushi Iwama;Channing Yu

  • Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice.

    D N Ernst;M V Hobbs;B E Torbett;A L Glasebrook

  • Virtual Screening for HIV Protease Inhibitors: A Comparison of AutoDock 4 and Vina

    Max W. Chang;Christian Ayeni;Sebastian Breuer;Bruce E. Torbett

  • A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

    Michael J. Giffin;Holly Heaslet;Ashraf Brik;Ying-Chuan Lin

  • Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

    Karen L. Anderson;Kent A. Smith;Kent A. Smith;Kris Conners;Kris Conners;Scott R. McKercher;Scott R. McKercher

  • Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates

    Donald E. Mosier;Richard J. Gulizia;Paul D. MacIsaac;Bruce E. Torbett

  • Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor

    Fouzia Amirache;Camille Lévy;Caroline Costa;Philippe-Emmanuel Mangeot

  • Transcription Factor PU.1 Is Necessary for Development of Thymic and Myeloid Progenitor-Derived Dendritic Cells

    Karen L. Anderson;Hugh Perkin;Charles D. Surh;Sara Venturini

  • Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBPε and PU.1

    Adrian F. Gombart;Scott H. Kwok;Karen L. Anderson;Yuji Yamaguchi

  • The Class I HLA Repertoire of Pancreatic Islets Comprises the Nonclassical Class Ib Antigen HLA-G

    Vincenzo Cirulli;Jessie Zalatan;Michael McMaster;Robyn Prinsen

  • Neutrophils Deficient in PU.1 Do Not Terminally Differentiate or Become Functionally Competent

    Karen L. Anderson;Kent A. Smith;Frederic Pio;Bruce E. Torbett

  • hu-PBL-SCID mice: a model for human immune function, AIDS, and lymphomagenesis.

    Bruce E. Torbett;Gaston Picchio;Donald E. Mosier

  • Presentation of chemokine SDF-1α by fibronectin mediates directed migration of T cells

    Anthony J. Pelletier;Luc J. W. van der Laan;Patrick Hildbrand;Michael A. Siani

  • CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus

    HyunJun Kang;Petra Minder;Mi Ae Park;Walatta-Tseyon Mesquitta

  • The Transcription Factor Encyclopedia

    Dimas Yusuf;Stefanie L. Butland;Magdalena I. Swanson;Eugene I. Bolotin

  • Additional file 4

    Dimas Yusuf;Stefanie L. Butland;Magdalena I. Swanson;Eugene Bolotin

Frequent Co-Authors

Martin F. Fey
Martin F. Fey University of Bern
John H. Elder
John H. Elder Scripps Research Institute
Donald E. Mosier
Donald E. Mosier Scripps Research Institute
Carlos F. Barbas
Carlos F. Barbas Scripps Research Institute
Robert F. Hevner
Robert F. Hevner University of California, San Diego
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Reiner A. Veitia
Reiner A. Veitia Université Paris Cité
Peggy J. Farnham
Peggy J. Farnham University of Southern California

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