D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 121 Citations 65,629 284 World Ranking 321 National Ranking 204
Biology and Biochemistry D-index 110 Citations 54,692 280 World Ranking 666 National Ranking 438

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

2014 - Fellow of the American Academy of Arts and Sciences

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Cancer

Her primary scientific interests are in Cell biology, Transcription factor, Hypoxia, Biochemistry and Regulation of gene expression. Her work deals with themes such as Embryonic stem cell, Angiogenesis and Molecular biology, which intersect with Cell biology. Her Angiogenesis study is related to the wider topic of Cancer research.

M. Celeste Simon interconnects Intestinal epithelium, Homeostasis and Conditional gene knockout in the investigation of issues within Transcription factor. The concepts of her Hypoxia study are interwoven with issues in Cell growth, Cancer cell, Immunology, CD38 and Cell type. Her Regulation of gene expression study integrates concerns from other disciplines, such as Phenotype, Erythropoiesis, Hypoxia-inducible factors, Disease and Gene isoform.

Her most cited work include:

  • Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase (1494 citations)
  • Hypoxia inducible factors and the response to hypoxic stress (1482 citations)
  • Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease (1403 citations)

What are the main themes of her work throughout her whole career to date?

M. Celeste Simon mostly deals with Cell biology, Cancer research, Hypoxia-inducible factors, Transcription factor and Molecular biology. Her Cell biology study incorporates themes from Embryonic stem cell, Endocrinology and Internal medicine, Angiogenesis. The Cancer research study combines topics in areas such as Carcinogenesis, Tumor progression, Immunology and Cell growth.

Her Hypoxia-inducible factors study combines topics from a wide range of disciplines, such as Inflammation, HIF1A and Pathology. Her Transcription factor research includes themes of Regulation of gene expression and Signal transduction. Her biological study spans a wide range of topics, including Cell culture and Transcription, Gene expression, Gene, Transactivation.

She most often published in these fields:

  • Cell biology (54.79%)
  • Cancer research (41.02%)
  • Hypoxia-inducible factors (29.64%)

What were the highlights of her more recent work (between 2015-2021)?

  • Cancer research (41.02%)
  • Cell biology (54.79%)
  • Cancer (8.08%)

In recent papers she was focusing on the following fields of study:

M. Celeste Simon mainly focuses on Cancer research, Cell biology, Cancer, Tumor microenvironment and Hypoxia. Her research integrates issues of Cell culture, Clear cell renal cell carcinoma, Metastasis, Sarcoma and Tumor progression in her study of Cancer research. Her Metastasis research focuses on EPAS1 and how it connects with Cell growth.

Her studies in Cell biology integrate themes in fields like Phenotype, Lipid metabolism, Transcription factor and Medical education. Her research in Tumor microenvironment intersects with topics in Liver cancer, Stromal cell, Gene expression and FBP1. The various areas that M. Celeste Simon examines in her Hypoxia study include Inflammation, Tumor tissue and Neuroscience.

Between 2015 and 2021, her most popular works were:

  • Glutathione metabolism in cancer progression and treatment resistance. (280 citations)
  • Oxygen availability and metabolic adaptations (195 citations)
  • Cellular adaptation to hypoxia through hypoxia inducible factors and beyond. (159 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

M. Celeste Simon mainly investigates Cancer research, Cancer, Cell biology, Cancer cell and Tumor microenvironment. Her studies in Cancer research integrate themes in fields like KRAS, Metastasis, Sarcoma and Enzyme. Her studies deal with areas such as Phenotype, Malignancy and Clear cell renal cell carcinoma as well as Cancer.

Her Cell biology study integrates concerns from other disciplines, such as Lipid metabolism and Cellular adaptation, Hypoxia. Her Cancer cell study incorporates themes from Glutathione, Angiogenesis, Antioxidant and Tumor initiation. The Immunology study combines topics in areas such as Transcription factor and Hypoxia-inducible factors.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

Joan E Durbin;Renée Hackenmiller;M.Celeste Simon;David E Levy.
Cell (1996)

1887 Citations

Hypoxia inducible factors and the response to hypoxic stress

Amar J. Majmundar;Waihay J. Wong;M. Celeste Simon.
Molecular Cell (2010)

1881 Citations

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

Tullia Lindsten;Andrea J. Ross;Ayala King;Wei Xing Zong.
Molecular Cell (2000)

1730 Citations

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

Brian Keith;Randall S. Johnson;M. Celeste Simon;M. Celeste Simon.
Nature Reviews Cancer (2012)

1677 Citations

Mop3 Is an Essential Component of the Master Circadian Pacemaker in Mammals

Maureen K. Bunger;Lisa D. Wilsbacher;Susan M. Moran;Cynthia Clendenin.
Cell (2000)

1623 Citations

Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation

Cheng-Jun Hu;Li-Yi Wang;Lewis A. Chodosh;Brian Keith.
Molecular and Cellular Biology (2003)

1586 Citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

Larysa Pevny;M. Celeste Simon;Elizabeth Robertson;William H. Klein.
Nature (1991)

1567 Citations

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Robert D. Guzy;Beatrice Hoyos;Emmanuel Robin;Hong Chen.
Cell Metabolism (2005)

1399 Citations

The impact of O2 availability on human cancer.

Jessica A. Bertout;Shetal A. Patel;M. Celeste Simon.
Nature Reviews Cancer (2008)

1318 Citations

Hypoxia-inducible factors, stem cells, and cancer.

Brian Keith;M. Celeste Simon;M. Celeste Simon.
Cell (2007)

1249 Citations

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