World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
21168
World Ranking
17818
National Ranking
7293

Brian Keith publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Brian Keith sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 67 publications — 1st percentile

1% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Brian Keith D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Brian Keith sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Brian Keith is affiliated with the University of Pennsylvania in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields, including cancer research, molecular biology, oncology, pulmonary and respiratory medicine, and epidemiology.

The scientist's research is focused primarily on cancer-related topics, particularly in areas involving cancer metabolism, hypoxia, lipid regulation, molecular pathways, and prognosis mechanisms such as ferroptosis. Key thematic areas also include renal cell carcinoma treatment, metabolomics and mass spectrometry studies, and RNA modifications relevant to cancer.

Brian Keith's publication record includes contributions to high-impact journals and prominent publication venues. Some of the recurrent outlets for their research include:

  • Cancer Research
  • Nature Cell Biology
  • Nature Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism

Recent notable papers authored or coauthored by Brian Keith cover diverse aspects of cancer biology and metabolism:

  • FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome, 2020, Nature Cell Biology
  • Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer, 2024, Nature Cancer
  • Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis, 2020, Cell Metabolism
  • ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism, 2021, Cancer & Metabolism
  • Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment, 2024, Cell Reports

Brian Keith collaborates frequently with several researchers, including M. Celeste Simon, Celeste Simon, Michelle Burrows, Clementina Mesaros, and Yanqing Jiang. These collaborations likely support investigations in cancer biology and metabolic regulation.

Best Publications

  • HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

    Brian Keith;Randall S. Johnson;M. Celeste Simon;M. Celeste Simon

  • Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation

    Cheng-Jun Hu;Li-Yi Wang;Lewis A. Chodosh;Brian Keith

  • Hypoxia-inducible factors, stem cells, and cancer.

    Brian Keith;M. Celeste Simon;M. Celeste Simon

  • Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

    Omkar U. Kawalekar;Roddy S. O’Connor;Joseph A. Fraietta;Lili Guo

  • The role of oxygen availability in embryonic development and stem cell function.

    M. Celeste Simon;Brian Keith

  • HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth

    Kelly L. Covello;James Kehler;Hongwei Yu;John D. Gordan

  • Hypoxia-induced energy stress regulates mRNA translation and cell growth.

    Liping Liu;Timothy P. Cash;Russell G. Jones;Brian Keith

  • Hypoxia-inducible factor–2 (HIF-2) regulates hepatic erythropoietin in vivo

    Erinn B. Rankin;Mangatt P. Biju;Qingdu Liu;Travis L. Unger

  • Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.

    Avery D. Posey;Robert D. Schwab;Alina C. Boesteanu;Catharina Steentoft

  • Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation.

    Sonia Guedan;Avery D. Posey;Carolyn Shaw;Anna Wing

  • HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

    John D. Gordan;Priti Lal;Vijay R. Dondeti;Richard Letrero

  • HIF-2α, but not HIF-1α, promotes iron absorption in mice

    Maria Mastrogiannaki;Pavle Matak;Brian Keith;M. Celeste Simon

  • Acute postnatal ablation of Hif-2α results in anemia

    Michaela Gruber;Cheng-Jun Hu;Randall S. Johnson;Eric J. Brown

  • Fructose-1,6-bisphosphatase opposes renal carcinoma progression

    Bo Li;Bo Qiu;David S. M. Lee;David S. M. Lee;Zandra E. Walton

  • Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

    Hongxia Z. Imtiyaz;Emily P. Williams;Michele M. Hickey;Shetal A. Patel

  • Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

    Biliang Hu;Jiangtao Ren;Yanping Luo;Brian Keith

  • Hypoxia-Inducible Factor 2 Regulates Hepatic Lipid Metabolism

    Erinn B. Rankin;Jennifer Rha;Mary A. Selak;Travis L. Unger

  • Oxygen availability and metabolic adaptations

    Michael S. Nakazawa;Brian Keith;M. Celeste Simon

  • Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia

    Pinelopi P. Kapitsinou;Qingdu Liu;Travis L. Unger;Jennifer Rha

  • HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

    Bo Qiu;Daniel Ackerman;Danielle J. Sanchez;Bo Li

Frequent Co-Authors

M. Celeste Simon
M. Celeste Simon University of Pennsylvania
Carl H. June
Carl H. June University of Pennsylvania
Itzhak Nissim
Itzhak Nissim Children's Hospital of Philadelphia
Anthony A. Mancuso
Anthony A. Mancuso University of Florida
J. Alan Diehl
J. Alan Diehl Case Western Reserve University
Randall S. Johnson
Randall S. Johnson University of Cambridge
Ian A. Blair
Ian A. Blair University of Pennsylvania
Katherine L. Nathanson
Katherine L. Nathanson University of Pennsylvania
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh

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