His scientific interests lie mostly in Pheochromocytoma, Internal medicine, Endocrinology, Paraganglioma and Nuclear medicine. His study in Pheochromocytoma is interdisciplinary in nature, drawing from both Mutation and Neuroendocrine tumors. His study looks at the relationship between Endocrinology and topics such as Multiple endocrine neoplasia type 2, which overlap with Gene mutation.
His work carried out in the field of Paraganglioma brings together such families of science as Germline mutation, SDHB, Malignancy, Somatic cell and Germline. He has included themes like Magnetic resonance imaging and Computed tomography in his Nuclear medicine study. His studies in Pathology integrate themes in fields like SDHA and Oncology.
Karel Pacak focuses on Pheochromocytoma, Internal medicine, Paraganglioma, Endocrinology and Pathology. His Pheochromocytoma study combines topics in areas such as Neuroendocrine tumors, Positron emission tomography, Radiology and Cancer research. His Positron emission tomography research is multidisciplinary, relying on both Magnetic resonance imaging, Functional imaging and Scintigraphy.
His work on Catecholamine, Epinephrine and Normetanephrine as part of general Internal medicine study is frequently connected to Context, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His studies deal with areas such as Genetics, Mutation, Germline mutation, SDHB and Disease as well as Paraganglioma. His research in Metanephrines intersects with topics in Metanephrine and Urology.
His primary areas of investigation include Paraganglioma, Pheochromocytoma, Cancer research, Internal medicine and SDHB. To a larger extent, Karel Pacak studies Pathology with the aim of understanding Paraganglioma. The various areas that Karel Pacak examines in his Pheochromocytoma study include Immunohistochemistry, Precision medicine, Germline mutation, Radiology and Metastasis.
His research in Internal medicine focuses on subjects like Cardiology, which are connected to Normetanephrine. His SDHB study also includes fields such as
Paraganglioma, Pheochromocytoma, Cancer research, Internal medicine and Neuroendocrine tumors are his primary areas of study. His Paraganglioma study contributes to a more complete understanding of Pathology. Karel Pacak undertakes interdisciplinary study in the fields of Pheochromocytoma and HRAS through his research.
His biological study spans a wide range of topics, including Acquired immune system, Toll-like receptor, Gene expression profiling, Mutation and EPAS1. Karel Pacak has researched Internal medicine in several fields, including Germline mutation, Endocrinology, Gastroenterology and Oncology. In Nuclear medicine, Karel Pacak works on issues like Guideline, which are connected to Positron emission tomography.
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Pheochromocytoma and paraganglioma: An endocrine society clinical practice guideline
Jacques W.M. Lenders;Quan Yang Duh;Graeme Eisenhofer;Anne Paule Gimenez-Roqueplo.
The Journal of Clinical Endocrinology and Metabolism (2014)
Biochemical diagnosis of pheochromocytoma: which test is best?
Jacques W. M. Lenders;Karel Pacak;McClellan M. Walther;W. Marston Linehan.
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf.
Stressor specificity of central neuroendocrine responses: implications for stress-related disorders.
Karel Pacák;Miklós Palkovits;Miklós Palkovits.
Endocrine Reviews (2001)
Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma.
Karel Pacak;W. Marston Linehan;Graeme Eisenhofer;McClellan M. Walther.
Annals of Internal Medicine (2001)
Pheochromocytoma: recommendations for clinical practice from the First International Symposium
Karel Pacak;Graeme Eisenhofer;Håkan Ahlman;Stefan R Bornstein.
Nature Clinical Practice Endocrinology & Metabolism (2007)
Cushing’s Syndrome Due to Ectopic Corticotropin Secretion: Twenty Years’ Experience at the National Institutes of Health
Ioannis Ilias;David J. Torpy;Karel Pacak;Nancy Mullen.
The Journal of Clinical Endocrinology and Metabolism (2005)
Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
Paul Lee;Joyce D. Linderman;Sheila Smith;Robert J. Brychta.
Cell Metabolism (2014)
Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction.
Barry A. Borlaug;Vojtech Melenovsky;Stuart D. Russell;Kristy Kessler.
An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.
Francien H van Nederveen;José Gaal;Judith Favier;Esther Korpershoek.
Lancet Oncology (2009)
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