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Medicine

D-Index
126
Citations
73486
World Ranking
2906
National Ranking
1612

Overview

Karel Pacak is affiliated with the National Institutes of Health in the United States and specializes in medicine with a focus on biochemistry, genetics, and molecular biology. Their work spans multiple subfields including surgery, endocrinology, diabetes and metabolism, cancer research, neurology, and oncology.

The primary research topics covered by Karel Pacak include adrenal and paraganglionic tumors, cancer, hypoxia, and metabolism, pituitary gland disorders and treatments, hormonal regulation and hypertension, neuroblastoma research and treatments, glioma diagnosis and treatment, and neuroendocrine tumor research advances.

Frequent collaborators in their research are:

  • Mercedes Robledo
  • Graeme Eisenhofer
  • Zhengping Zhuang
  • David Taïeb
  • Felix Beuschlein

Karel Pacak has published extensively in several academic journals, with notable frequent publication venues including:

  • Endocrine Related Cancer
  • Journal of the Endocrine Society
  • The Journal of Clinical Endocrinology & Metabolism
  • Frontiers in Endocrinology
  • Endocrine Abstracts

Significant papers authored or co-authored by Karel Pacak include:

  • "Genetics, diagnosis, management and future directions of research of phaeochromocytoma and paraganglioma: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension," 2020, Journal of Hypertension
  • "International consensus on initial screening and follow-up of asymptomatic SDHx mutation carriers," 2021, Nature Reviews Endocrinology
  • "Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma," 2023, Nature Communications
  • "New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications," 2022, Cancers
  • "Catecholamine physiology and its implications in patients with COVID-19," 2020, The Lancet Diabetes & Endocrinology

Best Publications

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pheochromocytoma and paraganglioma: An endocrine society clinical practice guideline

    Jacques W.M. Lenders;Quan Yang Duh;Graeme Eisenhofer;Anne Paule Gimenez-Roqueplo

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Biochemical diagnosis of pheochromocytoma: which test is best?

    Jacques W. M. Lenders;Karel Pacak;McClellan M. Walther;W. Marston Linehan

  • Stressor specificity of central neuroendocrine responses: implications for stress-related disorders.

    Karel Pacák;Miklós Palkovits;Miklós Palkovits

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma.

    Karel Pacak;W. Marston Linehan;Graeme Eisenhofer;McClellan M. Walther

  • Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

    Paul Lee;Joyce D. Linderman;Sheila Smith;Robert J. Brychta

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Cushing’s Syndrome Due to Ectopic Corticotropin Secretion: Twenty Years’ Experience at the National Institutes of Health

    Ioannis Ilias;David J. Torpy;Karel Pacak;Nancy Mullen

  • Pheochromocytoma: recommendations for clinical practice from the First International Symposium

    Karel Pacak;Graeme Eisenhofer;Håkan Ahlman;Stefan R Bornstein

  • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction.

    Barry A. Borlaug;Vojtech Melenovsky;Stuart D. Russell;Kristy Kessler

  • The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer.

    Herbert Chen;Rebecca S. Sippel;M. Sue O'Dorisio;Aaron I. Vinik

  • An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.

    Francien H van Nederveen;José Gaal;Judith Favier;Esther Korpershoek

  • Preoperative management of the pheochromocytoma patient.

    Karel Pacak

  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Lauren Fishbein;Lauren Fishbein;Ignaty Leshchiner;Ignaty Leshchiner;Vonn Walter;Vonn Walter;Ludmila Danilova;Ludmila Danilova

  • Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD.

    Barbara Pasini;Sarah R. McWhinney;Thalia Bei;Ludmila Matyakhina

  • Biochemical Diagnosis of Pheochromocytoma: How to Distinguish True- from False-Positive Test Results

    Graeme Eisenhofer;David S. Goldstein;McClellan M. Walther;Peter Friberg

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

Frequent Co-Authors

David S. Goldstein
David S. Goldstein National Institutes of Health
Zhengping Zhuang
Zhengping Zhuang National Institutes of Health
Electron Kebebew
Electron Kebebew Stanford University
Jacques W.M. Lenders
Jacques W.M. Lenders Radboud University
W. Marston Linehan
W. Marston Linehan National Institutes of Health
Massimo Mannelli
Massimo Mannelli University of Florence
Constantine A. Stratakis
Constantine A. Stratakis Foundation for Research and Technology Hellas
Irwin J. Kopin
Irwin J. Kopin National Institutes of Health
Felix Beuschlein
Felix Beuschlein University of Zurich

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