What is he best known for?
The fields of study he is best known for:
- Internal medicine
- Gene
- Cancer
His scientific interests lie mostly in Pheochromocytoma, Internal medicine, Endocrinology, Paraganglioma and Nuclear medicine.
His study in Pheochromocytoma is interdisciplinary in nature, drawing from both Mutation and Neuroendocrine tumors.
His study looks at the relationship between Endocrinology and topics such as Multiple endocrine neoplasia type 2, which overlap with Gene mutation.
His work carried out in the field of Paraganglioma brings together such families of science as Germline mutation, SDHB, Malignancy, Somatic cell and Germline.
He has included themes like Magnetic resonance imaging and Computed tomography in his Nuclear medicine study.
His studies in Pathology integrate themes in fields like SDHA and Oncology.
His most cited work include:
- Pheochromocytoma and paraganglioma: An endocrine society clinical practice guideline (1086 citations)
- Biochemical diagnosis of pheochromocytoma: which test is best? (853 citations)
- Stressor specificity of central neuroendocrine responses: implications for stress-related disorders. (747 citations)
What are the main themes of his work throughout his whole career to date?
Karel Pacak focuses on Pheochromocytoma, Internal medicine, Paraganglioma, Endocrinology and Pathology.
His Pheochromocytoma study combines topics in areas such as Neuroendocrine tumors, Positron emission tomography, Radiology and Cancer research.
His Positron emission tomography research is multidisciplinary, relying on both Magnetic resonance imaging, Functional imaging and Scintigraphy.
His work on Catecholamine, Epinephrine and Normetanephrine as part of general Internal medicine study is frequently connected to Context, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His studies deal with areas such as Genetics, Mutation, Germline mutation, SDHB and Disease as well as Paraganglioma.
His research in Metanephrines intersects with topics in Metanephrine and Urology.
He most often published in these fields:
- Pheochromocytoma (48.27%)
- Internal medicine (41.76%)
- Paraganglioma (35.55%)
What were the highlights of his more recent work (between 2018-2021)?
- Paraganglioma (35.55%)
- Pheochromocytoma (48.27%)
- Cancer research (16.62%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Paraganglioma, Pheochromocytoma, Cancer research, Internal medicine and SDHB.
To a larger extent, Karel Pacak studies Pathology with the aim of understanding Paraganglioma.
The various areas that Karel Pacak examines in his Pheochromocytoma study include Immunohistochemistry, Precision medicine, Germline mutation, Radiology and Metastasis.
His research in Internal medicine focuses on subjects like Cardiology, which are connected to Normetanephrine.
His SDHB study also includes fields such as
- SDHA most often made with reference to SDHD,
- Metabolomics most often made with reference to Succinate dehydrogenase.
His work on Brown adipose tissue is typically connected to Context as part of general Endocrinology study, connecting several disciplines of science.
Between 2018 and 2021, his most popular works were:
- Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. (71 citations)
- European Association of Nuclear Medicine Practice Guideline/Society of Nuclear Medicine and Molecular Imaging Procedure Standard 2019 for radionuclide imaging of phaeochromocytoma and paraganglioma. (50 citations)
- Current Management of Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician in the Era of Precision Medicine. (36 citations)
In his most recent research, the most cited papers focused on:
- Internal medicine
- Gene
- Cancer
Paraganglioma, Pheochromocytoma, Cancer research, Internal medicine and Neuroendocrine tumors are his primary areas of study.
His Paraganglioma study contributes to a more complete understanding of Pathology.
Karel Pacak undertakes interdisciplinary study in the fields of Pheochromocytoma and HRAS through his research.
His biological study spans a wide range of topics, including Acquired immune system, Toll-like receptor, Gene expression profiling, Mutation and EPAS1.
Karel Pacak has researched Internal medicine in several fields, including Germline mutation, Endocrinology, Gastroenterology and Oncology.
In Nuclear medicine, Karel Pacak works on issues like Guideline, which are connected to Positron emission tomography.
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