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Immunology

D-Index
66
Citations
14264
World Ranking
2774
National Ranking
58

Overview

Jan Ernerudh is affiliated with Linköping University in Sweden and works primarily within the fields of Medicine and Immunology and Microbiology. Their research explores several subfields, with a focus on Immunology, Obstetrics and Gynecology, Molecular Biology, Epidemiology, and Pulmonary and Respiratory Medicine.

Their scientific contributions address a variety of main topics including:

  • Reproductive System and Pregnancy
  • Pregnancy and preeclampsia studies
  • Preterm Birth and Chorioamnionitis
  • Neonatal Respiratory Health Research
  • Multiple Sclerosis Research Studies
  • Menopause: Health Impacts and Treatments
  • Immunodeficiency and Autoimmune Disorders

Ernerudh's recent papers illustrate a strong interest in immunological mechanisms and biomarkers related to pregnancy complications, autoimmune diseases, and neurological conditions. Notable publications include:

  • "Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis," published in 2023 in Nature Communications
  • "Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy," published in 2021 in Frontiers in Immunology
  • "Decidual stromal cells support tolerance at the human foetal-maternal interface by inducing regulatory M2 macrophages and regulatory T-cells," published in 2021 in Journal of Reproductive Immunology
  • "Novel blood test for early biomarkers of preeclampsia and Alzheimer's disease," published in 2021 in Scientific Reports
  • "The human placenta shapes the phenotype of decidual macrophages," published in 2023 in Cell Reports

Ernerudh frequently publishes in scientific journals such as:

  • Frontiers in Immunology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Journal of Reproductive Immunology

Collaborations are a significant feature of their research, with frequent co-authors including Maria C. Jenmalm, Johanna Raffetseder, Mika Gustafsson, Sandra Hellberg, and Johan Mellergård. These collaborations encompass a broad span of immunological and reproductive health topics.

Best Publications

  • An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

    Anders Wikby;Frederick Ferguson;Rosalyn Forsey;Julie Thompson

  • Seminal plasma proteins: what role do they play?

    Heriberto Rodríguez-Martínez;Ulrik Kvist;Jan Ernerudh;Libia Sanz

  • Gene expression profiling of human decidual macrophages: evidence for immunosuppressive phenotype.

    Charlotte Gustafsson;Jenny Mjösberg;Andreas Matussek;Robert Geffers

  • Macrophages at the Fetal–Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10

    Judit Svensson;Maria C. Jenmalm;Andreas Matussek;Robert Geffers

  • FOXP3+ Regulatory T Cells and T Helper 1, T Helper 2, and T Helper 17 Cells in Human Early Pregnancy Decidua

    Jenny Mjösberg;Göran Berg;Maria C. Jenmalm;Jan Ernerudh

  • The Human Fetal Placenta Promotes Tolerance against the Semiallogeneic Fetus by Inducing Regulatory T Cells and Homeostatic M2 Macrophages

    Judit Svensson-Arvelund;Ratnesh B. Mehta;Robert Lindau;Elahe Mirrasekhian

  • Cytokine mapping of sera from women with preeclampsia and normal pregnancies

    Yvonne Jonsson;Marie Rubèr;Leif Matthiesen;Göran Berg

  • The immune risk phenotype is associated with IL-6 in the terminal decline stage: findings from the Swedish NONA immune longitudinal study of very late life functioning.

    Anders Wikby;Bengt-Olof Nilsson;Rosalyn Forsey;Julie Thompson

  • Plasma cytokine profiles in elderly humans.

    R J Forsey;J M Thompson;J Ernerudh;T L Hurst

  • Immunology of Preeclampsia

    Leif Matthiesen;Göran Berg;Jan Ernerudh;Christina Ekerfelt

  • No Immune Risk Profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study.

    Jan Strindhall;Bengt-Olof Nilsson;Sture Löfgren;Jan Ernerudh

  • The inverted CD4/CD8 ratio and associated parameters in 66-year-old individuals: the Swedish HEXA immune study

    Jan Strindhall;Mårten Skog;Jan Ernerudh;M Bengner

  • Systemic Reduction of Functionally Suppressive CD4dimCD25highFoxp3+ Tregs in Human Second Trimester Pregnancy Is Induced by Progesterone and 17β-Estradiol

    Jenny Mjösberg;Judit Svensson;Emma Johansson;Lotta Hellström

  • Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid

    Johan Mellergård;Måns Edström;Magnus Vrethem;Jan Ernerudh

  • Cytokine secretion patterns of NK cells and macrophages in early human pregnancy decidua and blood: implications for suppressor macrophages in decidua.

    C Lidström;L Matthiesen;G Berg;S Sharma

  • Interleukin-6 levels in relation to psychosocial factors: Studies on serum, saliva, and in vitro production by blood mononuclear cells

    Elaine Sjögren;Per Leanderson;Margareta Kristenson;Jan Ernerudh

  • Lyme neuroborreliosis in children: a prospective study of clinical features, prognosis, and outcome.

    Barbro Hedin Skogman;Stefan Croner;Maria Nordwall;Mattias Eknefelt

  • Subclinical myositis is common in primary Sjögren's syndrome and is not related to muscle pain.

    Bjorn Lindvall;Ann Bengtsson;Jan Ernerudh;Per Eriksson

  • The placenta in toxicology. Part II : Systemic and local immune adaptations in pregnancy

    Judit Svensson-Arvelund;Jan Ernerudh;Eberhard Buse;J Mark Cline

  • Lymphocyte subsets and mitogen stimulation of blood lymphocytes in normal pregnancy.

    Leif Matthiesen;Göran Berg;Jan Ernerudh;Leif Håkansson

  • Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis

    Irene Håkansson;Anders Tisell;Petra Cassel;Kaj Blennow;Kaj Blennow

Frequent Co-Authors

Maria C. Jenmalm
Maria C. Jenmalm Linköping University
Sven Bergström
Sven Bergström Umeå University
Surendra Sharma
Surendra Sharma Brown University
Jenny Mjösberg
Jenny Mjösberg Karolinska Institute
Tomas Olsson
Tomas Olsson Karolinska Institute
Boo Johansson
Boo Johansson University of Gothenburg
Per Eriksson
Per Eriksson Karolinska University Hospital
Lennart Nilsson
Lennart Nilsson Karolinska Institute
Mikael Benson
Mikael Benson Linköping University
Jesper Tegnér
Jesper Tegnér King Abdullah University of Science and Technology

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