World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16871
World Ranking
6698
National Ranking
3112

Overview

Yatrik M. Shah is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine. Within these broad domains, Shah's work includes significant contributions to molecular biology, cancer research, oncology, hematology, and genetics.

The scientist's main research themes focus on cancer, hypoxia, and metabolism; iron metabolism and related disorders; ferroptosis and cancer prognosis; epigenetics and DNA methylation; hemoglobinopathies and related disorders; gut microbiota and health; and pancreatic and hepatic oncology research.

Shah has contributed to numerous scientific articles published across a variety of journals. Frequently published venues include bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Blood, Journal of Biological Chemistry, and Gastroenterology.

Recent papers authored or co-authored by Shah feature the following titles and publication years:

  • CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4, 2022, Cancer Cell
  • Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine, 2020, Journal of Biological Chemistry
  • Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance, 2021, Cancer Cell
  • GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis, 2021, Nature Communications
  • Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment, 2021, Nature Reviews Cancer

The scientist collaborates frequently with multiple co-authors, notable among them are Costas A. Lyssiotis, Nupur K. Das, Sumeet Solanki, Brandon Chen, and Rashi Singhal.

Best Publications

  • The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention

    Jeffrey M. Peters;Yatrik M. Shah;Frank J. Gonzalez

  • Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

    Yatrik M. Shah;Tsutomu Matsubara;Shinji Ito;Sun Hee Yim

  • Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

    Insook Kim;Keiichirou Morimura;Yatrik Shah;Qian Yang

  • Peroxisome Proliferator-Activated Receptor α Regulates a MicroRNA-Mediated Signaling Cascade Responsible for Hepatocellular Proliferation

    Yatrik M. Shah;Keiichirou Morimura;Qian Yang;Tomotaka Tanabe

  • PPARα: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

    Frank J. Gonzalez;Yatrik M. Shah

  • Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

    Kim Cheng;Kenneth Ho;Rebecca Stokes;Christopher Scott

  • Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

    Matthew Taylor;Aijuan Qu;Erik R. Anderson;Tsutomu Matsubara

  • Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression

    Yatrik M. Shah;Xiaochao Ma;Keiichirou Morimura;Insook Kim

  • Peroxisome proliferator activated receptor γ in colonic epithelial cells protects against experimental inflammatory bowel disease

    Masahiro Adachi;Reiko Kurotani;Keiichiro Morimura;Yatrik Shah

  • Iron homeostasis in the liver.

    Erik R Anderson;Yatrik M Shah

  • Serum metabolomics reveals irreversible inhibition of fatty acid β-oxidation through the suppression of PPARα activation as a contributing mechanism of acetaminophen-induced hepatotoxicity

    Chi Chen;Kristopher W. Krausz;Yatrik M. Shah;Jeffrey R. Idle

  • Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine

    Rashi Singhal;Yatrik M. Shah

  • Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.

    Nupur K. Das;Andrew J. Schwartz;Gabrielle Barthel;Naohiro Inohara

  • Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis

    Xiang Xue;Sadeesh K. Ramakrishnan;Kevin Weisz;Daniel Triner

  • Hypoxia-inducible factors: a central link between inflammation and cancer

    Daniel Triner;Yatrik M. Shah

  • Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

    Huabing Zhang;Sadeesh K. Ramakrishnan;Daniel Triner;Brook Centofanti

  • Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice

    Xiang Xue;Sadeesh Ramakrishnan;Erik Anderson;Matthew Taylor

  • Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.

    Chi Chen;Yatrik M. Shah;Keiichirou Morimura;Kristopher W. Krausz

  • Pregnane X receptor as a target for treatment of inflammatory bowel disorders

    Jie Cheng;Yatrik M. Shah;Frank J. Gonzalez

  • Hypoxia-Inducible Factor Augments Experimental Colitis Through an MIF-Dependent Inflammatory Signaling Cascade

    Yatrik M. Shah;Shinji Ito;Keiichirou Morimura;Chi Chen

Frequent Co-Authors

Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Kristopher W. Krausz
Kristopher W. Krausz National Institutes of Health
Costas A. Lyssiotis
Costas A. Lyssiotis University of Michigan–Ann Arbor
M. Bishr Omary
M. Bishr Omary University of Michigan–Ann Arbor
Jeffrey R. Idle
Jeffrey R. Idle University of Bern
Liangyou Rui
Liangyou Rui University of Michigan–Ann Arbor
Joel K. Greenson
Joel K. Greenson University of Michigan–Ann Arbor
Jason R. Spence
Jason R. Spence University of Michigan–Ann Arbor
Stefano Rivella
Stefano Rivella Children's Hospital of Philadelphia
Chi Chen
Chi Chen University of Minnesota

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