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Liangyou Rui

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
13207
World Ranking
14893
National Ranking
6236

Liangyou Rui publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Liangyou Rui sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 124 publications — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Liangyou Rui D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Liangyou Rui sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Liangyou Rui is a researcher affiliated with the University of Michigan-Ann Arbor in the United States. Their research focuses primarily on biochemistry, genetics, molecular biology, and medicine, with 38 publications in each of these main fields. The scientist's work spans multiple subfields including molecular biology, physiology, cancer research, epidemiology, and endocrine and autonomic systems.

The main topics of research include adipose tissue and metabolism, regulation of appetite and obesity, liver disease diagnosis and treatment, RNA modifications and cancer, epigenetics and DNA methylation, endoplasmic reticulum stress and disease, as well as liver physiology and pathology.

Liangyou Rui has contributed to a number of scientific papers. Some recent publications are:

  • Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease, 2020, Nature Communications
  • Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes, 2020, Journal of Clinical Investigation
  • Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis, 2022, Nature Metabolism
  • Reprogramming of Hepatic Metabolism and Microenvironment in Nonalcoholic Steatohepatitis, 2022, Annual Review of Nutrition
  • Biliary NIK promotes ductular reaction and liver injury and fibrosis in mice, 2022, Nature Communications

The frequent publication venues for Liangyou Rui include:

  • Diabetes
  • Nature Communications
  • Advanced Science
  • Journal of Clinical Investigation
  • Nature Metabolism

Frequent co-authors collaborating with Liangyou Rui are:

  • Lin Jiang
  • Min-Hyun Kim
  • Zhiguo Zhang
  • Xiao Yan Zhong
  • Hong Shen

Liangyou Rui was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • Energy metabolism in the liver

    Liangyou Rui

  • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.

    Liangyou Rui;Minsheng Yuan;Daniel Frantz;Steven Shoelson

  • Insulin/IGF-1 and TNF-α stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

    Liangyou Rui;Vincent Aguirre;Jason K. Kim;Gerald I. Shulman

  • Recent advances in understanding leptin signaling and leptin resistance

    David L. Morris;Liangyou Rui

  • Leptin signaling and leptin resistance.

    Yingjiang Zhou;Liangyou Rui

  • The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

    Bo Shan;Xiaoxia Wang;Ying Wu;Chi Xu

  • Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice.

    Decheng Ren;Minghua Li;Chaojun Duan;Liangyou Rui

  • Neuronal SH2B1 is essential for controlling energy and glucose homeostasis

    Decheng Ren;Yingjiang Zhou;David Morris;Minghua Li

  • Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.

    Liangyou Rui;Tracey L. Fisher;Jeffrey Thomas;Morris F. White

  • Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice†

    Qiong Wang;Lei Jiang;Jue Wang;Shoufeng Li

  • Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.

    L Rui;L S Mathews;K Hotta;T A Gustafson

  • Human SH2B1 mutations are associated with maladaptive behaviors and obesity

    Michael E. Doche;Elena G. Bochukova;Hsiao Wen Su;Laura R. Pearce

  • SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin

    Chaojun Duan;Minghua Li;Liangyou Rui

  • Identification of SH2-Bβ as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2

    Liangyou Rui;Christin Carter-Su

  • Brown and Beige Adipose Tissues in Health and Disease.

    Liangyou Rui

  • Identification of MUP1 as a regulator for glucose and lipid metabolism in mice.

    Yingjiang Zhou;Lin Jiang;Liangyou Rui

  • Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s–PPARα axis signalling

    Mengle Shao;Bo Shan;Yang Liu;Yiping Deng

  • Disruption of the SH2-B Gene Causes Age-Dependent Insulin Resistance and Glucose Intolerance

    Chaojun Duan;Hongyan Yang;Morris F. White;Liangyou Rui

  • Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.

    Xin Tong;Marina Muchnik;Zheng Chen;Manish Patel

  • SH2-B is required for nerve growth factor-induced neuronal differentiation.

    Liangyou Rui;James Herrington;Christin Carter-Su

Frequent Co-Authors

Christin Carter-Su
Christin Carter-Su University of Michigan–Ann Arbor
Morris F. White
Morris F. White Boston Children's Hospital
Inês Barroso
Inês Barroso University of Exeter
Yatrik M. Shah
Yatrik M. Shah University of Michigan–Ann Arbor
David L. Morris
David L. Morris University of New South Wales
I. Sadaf Farooqi
I. Sadaf Farooqi University of Cambridge
Ying Wu
Ying Wu Northwestern University
M. Bishr Omary
M. Bishr Omary University of Michigan–Ann Arbor
Wen-Jun Li
Wen-Jun Li Sun Yat-sen University
Stephen O'Rahilly
Stephen O'Rahilly University of Cambridge

External Links

Personal website of Liangyou Rui

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Related Online Degrees & Career Pathways

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By aligning your degree choice with your career interests, online pathways make it possible to gain specialized knowledge and skills in the growing fields related to Biology and Biochemistry.

Best Scientists Citing Liangyou Rui

Morris F. White

Morris F. White

Boston Children's Hospital

Publications: 35

Christin Carter-Su

Christin Carter-Su

University of Michigan–Ann Arbor

Publications: 33

Laurie J. Goodyear

Laurie J. Goodyear

Harvard University

Publications: 29

Stuart J. Frank

Stuart J. Frank

University of Alabama at Birmingham

Publications: 20

David Meyre

David Meyre

University of Lorraine

Publications: 20

Jason K. Kim

Jason K. Kim

University of Massachusetts Chan Medical School

Publications: 19

Philippe Froguel

Philippe Froguel

Imperial College London

Publications: 19

Lício A. Velloso

Lício A. Velloso

State University of Campinas

Publications: 19

Martin G. Myers

Martin G. Myers

University of Toronto

Publications: 19

Norbert Perrimon

Norbert Perrimon

Harvard University

Publications: 16

Michael F. Hirshman

Michael F. Hirshman

Harvard University

Publications: 16

Akihiko Yoshimura

Akihiko Yoshimura

Keio University

Publications: 15

Paresh Dandona

Paresh Dandona

University at Buffalo, State University of New York

Publications: 15

Gerald I. Shulman

Gerald I. Shulman

Yale University

Publications: 15

Florian Lang

Florian Lang

University of Tübingen

Publications: 14

Gökhan S. Hotamisligil

Gökhan S. Hotamisligil

Harvard University

Publications: 14

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