2026 Jason R. Spence: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	73	5860	5406	2776	2492	222	22876

Overview

Jason R. Spence is affiliated with the University of Michigan-Ann Arbor in the United States. Their research covers key areas within medicine and biochemistry, genetics, and molecular biology, focusing extensively on molecular biology and its applications.

The scientist's fields of study include:

Medicine
Biochemistry, Genetics and Molecular Biology

Within these broader fields, their work delves into specific subfields such as:

Molecular Biology
Surgery
Pulmonary and Respiratory Medicine
Oncology
Genetics

Jason R. Spence's main research topics span across several areas:

Renal and related cancers
Neonatal Respiratory Health Research
Cancer Cells and Metastasis
Congenital Diaphragmatic Hernia Studies
Digestive system and related health
Single-cell and spatial transcriptomics
Pluripotent Stem Cells Research

Their frequent co-authors include:

Angeline Wu
Yu-Hwai Tsai
Tristan Frum
Emily M. Holloway
Sha Huang

Jason R. Spence has published extensively in well-known venues, with the most frequent being:

bioRxiv (Cold Spring Harbor Laboratory)
Cell stem cell
Development
Developmental Cell
Nature

Some notable recent papers include:

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19, 2020, published in Immunity
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor, 2022, published in Nature
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis, 2020, published in Nature
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells, 2020, published in Cell stem cell
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19, 2021, published in Proceedings of the National Academy of Sciences

Best Publications

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

2401
Citations
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

Jason R. Spence;Christopher N. Mayhew;Scott A. Rankin;Matthew F. Kuhar

1925
Citations
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

Kyle W. McCracken;Emily M. Catá;Calyn M. Crawford;Katie L. Sinagoga

944
Citations
In vitro generation of human pluripotent stem cell derived lung organoids

Briana R Dye;David R Hill;Michael A H Ferguson;Yu-Hwai Tsai

773
Citations
An in vivo model of human small intestine using pluripotent stem cells

Carey L Watson;Maxime M Mahe;Jorge Múnera;Jonathan C Howell

572
Citations
Facile isolation and the characterization of human retinal stem cells

Brenda L. K. Coles;Brigitte Angénieux;Tomoyuki Inoue;Katia Del Rio-Tsonis

501
Citations
Synthetic hydrogels for human intestinal organoid generation and colonic wound repair

Ricardo Cruz-Acuña;Miguel Quirós;Attila E. Farkas;Priya H. Dedhia

433
Citations
Generating human intestinal tissue from pluripotent stem cells in vitro.

Kyle W McCracken;Jonathan C Howell;James M Wells;Jason R Spence

433
Citations
Sox17 and Sox4 Differentially Regulate β-Catenin/T-Cell Factor Activity and Proliferation of Colon Carcinoma Cells

Débora Sinner;Jennifer J. Kordich;Jason R. Spence;Robert Opoka

380
Citations
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

Joana P. Bernardes;Neha Mishra;Florian Tran;Thomas Bahmer

377
Citations
Sox17 Regulates Organ Lineage Segregation of Ventral Foregut Progenitor Cells

Jason R. Spence;Alex W. Lange;Suh Chin J. Lin;Klaus H. Kaestner

335
Citations
Generation of lung organoids from human pluripotent stem cells in vitro.

Alyssa J. Miller;Briana R. Dye;Daysha Ferrer-Torres;David R. Hill

333
Citations
Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function

Jhansi L. Leslie;Sha Huang;Judith S. Opp;Melinda S. Nagy

323
Citations
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

Briana E. Rockich;Steven M. Hrycaj;Hung Ping Shih;Melinda S. Nagy

276
Citations
Organoid Models of Human Gastrointestinal Development and Disease.

Priya H. Dedhia;Nina Bertaux-Skeirik;Yana Zavros;Jason R. Spence

260
Citations
Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo

Stacy R. Finkbeiner;David R. Hill;Christopher H. Altheim;Priya H. Dedhia

245
Citations
Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.

Jorge O. Múnera;Nambirajan Sundaram;Scott A. Rankin;David Hill

238
Citations
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.

Nupur K. Das;Andrew J. Schwartz;Gabrielle Barthel;Naohiro Inohara

228
Citations
Vertebrate intestinal endoderm development

Jason R. Spence;Ryan Lauf;Noah F. Shroyer

221
Citations
In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells

Alyssa J. Miller;David R. Hill;Melinda S. Nagy;Yoshiro Aoki

219
Citations