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Darrell N. Kotton

Darrell N. Kotton

D-Index & Metrics

Molecular Biology

D-Index
71
Citations
17735
World Ranking
1379
National Ranking
700

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Darrell N. Kotton is affiliated with Boston University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on Pulmonary and Respiratory Medicine, Molecular Biology, Infectious Diseases, Surgery, and Immunology.

The scientist's work covers several main topics, including:

  • Neonatal Respiratory Health Research
  • SARS-CoV-2 and COVID-19 Research
  • Renal and related cancers
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Energy Harvesting in Wireless Networks
  • Congenital Diaphragmatic Hernia Studies
  • Medical Imaging and Pathology Studies

Some of their recent publications are:

  • "The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future," 2020, published in Cell Stem Cell
  • "SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response," 2020, published in Cell Stem Cell
  • "Human distal airways contain a multipotent secretory cell that can regenerate alveoli," 2022, published in Nature
  • "SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes," 2021, published in Proceedings of the National Academy of Sciences
  • "Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells," 2021, published in Nature Cell Biology

Their frequent co-authors include Jessie Huang, Carlos Villacorta-Martín, Konstantinos-Dionysios Alysandratos, Finn Hawkins, and Andrew A. Wilson. Their collaboration with these researchers reflects a sustained contribution to the fields related to lung biology and respiratory diseases.

Darrell N. Kotton has published extensively in several venues, with notable frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Stem Cell
  • American Journal of Respiratory and Critical Care Medicine
  • Nature
  • Nature Communications

The scientist has been recognized as a member of the Association of American Physicians.

Best Publications

  • Telomere dysfunction induces metabolic and mitochondrial compromise

    Ergiin Sahin;Simona Colla;Marc Liesa;Javid Moslehi

  • Regeneration and orthotopic transplantation of a bioartificial lung

    Harald C Ott;Ben Clippinger;Claudius Conrad;Christian Schuetz

  • Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

    Cesar A. Sommer;Matthias Stadtfeld;George J. Murphy;Konrad Hochedlinger

  • Bone marrow-derived cells as progenitors of lung alveolar epithelium.

    Darrell N. Kotton;Bei Yang Ma;Wellington V. Cardoso;Elisabeth A. Sanderson

  • Lung regeneration: mechanisms, applications and emerging stem cell populations

    Darrell N Kotton;Edward E Morrisey

  • Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette

    Aba Somers;Jyh‐Chang Jean;Cesar A. Sommer;Amel Omari

  • Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

    Anjali Jacob;Anjali Jacob;Michael Morley;Finn Hawkins;Finn Hawkins;Katherine B. McCauley;Katherine B. McCauley

  • Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells.

    Tyler A. Longmire;Tyler A. Longmire;Laertis Ikonomou;Laertis Ikonomou;Finn Hawkins;Finn Hawkins;Constantina Christodoulou;Constantina Christodoulou

  • Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.

    Katherine B. McCauley;Finn Hawkins;Finn Hawkins;Maria Serra;Maria Serra;Dylan C. Thomas

  • SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

    Jessie Huang;Jessie Huang;Adam J. Hume;Kristine M. Abo;Kristine M. Abo;Rhiannon B. Werder;Rhiannon B. Werder;Rhiannon B. Werder

  • The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.

    Maria C. Basil;Jeremy Katzen;Anna E. Engler;Minzhe Guo

  • Excision of Reprogramming Transgenes Improves the Differentiation Potential of iPS Cells Generated with a Single Excisable Vector

    Cesar A. Sommer;Andreia Gianotti Sommer;Tyler A. Longmire;Constantina Christodoulou

  • Side population cells and Bcrp1 expression in lung

    Ross Summer;Darrell N. Kotton;Xi Sun;Bei Ma

  • Failure of bone marrow to reconstitute lung epithelium.

    Darrell N. Kotton;Attila J. Fabian;Richard C. Mulligan

  • Self-renewing endodermal progenitor lines generated from human pluripotent stem cells.

    Xin Cheng;Lei Ying;Lin Lu;Aline M. Galvão

  • SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes.

    Yize Li;David M. Renner;Courtney E. Comar;Jillian N. Whelan

  • The Prolonged Life-Span of Alveolar Macrophages

    Jaime Murphy;Ross Summer;Andrew A. Wilson;Darrell N. Kotton

  • miR-129 regulates cell proliferation by downregulating Cdk6 expression

    Junjie Wu;Jun Qian;Chun Li;Letty Kwok

  • Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.

    Cecile Terrenoire;Kai Wang;Kelvin W. Chan Tung;Wendy K. Chung

  • Figure 3, A.

    Wellington V Cardoso;Darrell N Kotton

Frequent Co-Authors

Gustavo Mostoslavsky
Gustavo Mostoslavsky Boston University
Edward E. Morrisey
Edward E. Morrisey University of Pennsylvania
Wellington V. Cardoso
Wellington V. Cardoso Columbia University
Richard C. Mulligan
Richard C. Mulligan Harvard University
Andrew Emili
Andrew Emili Boston University
Orian S. Shirihai
Orian S. Shirihai University of California, Los Angeles
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai
Michael F. Beers
Michael F. Beers University of Pennsylvania
Gordon Keller
Gordon Keller University of Toronto
Joseph P. Mizgerd
Joseph P. Mizgerd Boston University

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