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Biology and Biochemistry

D-Index
94
Citations
36532
World Ranking
1988
National Ranking
1083

Overview

Scott H. Randell is a researcher affiliated with the University of North Carolina at Chapel Hill in the United States. Their work focuses primarily on the field of medicine, with significant contributions to pulmonary and respiratory medicine, molecular biology, infectious diseases, epidemiology, and surgery.

The scientist's research covers several main topics, including:

  • Neonatal Respiratory Health Research
  • Cystic Fibrosis Research Advances
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory viral infections research
  • Tracheal and airway disorders
  • Viral gastroenteritis research and epidemiology
  • Energy Harvesting in Wireless Networks

Among recent publications attributed to the research network associated with Randell, notable studies include:

  • "SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract," 2020, published in Cell
  • "SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo," 2020, published in Science
  • "Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction," 2020, published in Cell Stem Cell
  • "Human distal lung maps and lineage hierarchies reveal a bipotent progenitor," 2022, published in Nature
  • "Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells," 2020, published in Cell Stem Cell

Frequent collaborators in their research include:

  • Richard C. Boucher
  • Kenichi Okuda
  • Ralph S. Baric
  • Rhianna E. Lee
  • Hong Dang

Scott H. Randell's publications appear regularly in several venues, including:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cystic Fibrosis
  • American Journal of Respiratory and Critical Care Medicine
  • American Journal of Respiratory Cell and Molecular Biology

Their significant volume of work spans areas impacting respiratory health, infectious disease pathology, and molecular mechanisms underlying pulmonary function and dysfunction.

Best Publications

  • Type 2 alveolar cells are stem cells in adult lung

    Christina E. Barkauskas;Michael J. Cronce;Craig R. Rackley;Emily J. Bowie

  • SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

    Yixuan J. Hou;Kenichi Okuda;Caitlin E. Edwards;David R. Martinez

  • Basal cells as stem cells of the mouse trachea and human airway epithelium

    Jason R. Rock;Mark W. Onaitis;Emma L. Rawlins;Yun Lu

  • Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

    Dieter Worlitzsch;Robert Tarran;Martina Ulrich;Ute Schwab

  • Evidence for Periciliary Liquid Layer Depletion, Not Abnormal Ion Composition, in the Pathogenesis of Cystic Fibrosis Airways Disease

    Hirotoshi Matsui;Barbara R Grubb;Robert Tarran;Scott H Randell

  • A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

    Vineet D. Menachery;Boyd L. Yount;Kari Debbink;Sudhakar Agnihothram

  • Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.

    Brigid L.M. Hogan;Christina E. Barkauskas;Harold A. Chapman;Jonathan A. Epstein

  • SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

    Yixuan J. Hou;Shiho Chiba;Peter Halfmann;Camille Ehre

  • Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

    Jason R. Rock;Scott H. Randell;Brigid L. M. Hogan

  • Evidence for stem-cell niches in the tracheal epithelium.

    D W Borthwick;M Shahbazian;Q T Krantz;J R Dorin

  • Notch-dependent differentiation of adult airway basal stem cells.

    Jason R. Rock;Xia Gao;Yan Xue;Scott H. Randell

  • Coordinated clearance of periciliary liquid and mucus from airway surfaces.

    H Matsui;S H Randell;S W Peretti;C W Davis

  • Airway epithelial cells: current concepts and challenges.

    Ronald G. Crystal;Scott H. Randell;John F. Engelhardt;Judith Voynow

  • Effective Mucus Clearance Is Essential for Respiratory Health

    Scott H. Randell;Richard C. Boucher

  • Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer.

    Raymond J. Pickles;Douglas McCarty;Hirotoshi Matsui;Pádraig J. Hart

  • Activation of Toll-Like Receptor 2 on Human Tracheobronchial Epithelial Cells Induces the Antimicrobial Peptide Human β Defensin-2

    Cheryl J. Hertz;Qi Wu;Edith Martin Porter;Yan J. Zhang

  • Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus.

    S. J. Anthony;S. J. Anthony;Kirsten Vk Gilardi;V. D. Menachery;Tracey Goldstein

  • Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

    Deborah M. Cholon;Nancy L. Quinney;M. Leslie Fulcher;Charles R. Esther

  • Human nasal and tracheo-bronchial respiratory epithelial cell culture

    M. Leslie Fulcher;Scott H. Randell

  • Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.

    Vonn Walter;Xiaoying Yin;Matthew D. Wilkerson;Christopher R. Cabanski;Christopher R. Cabanski

Frequent Co-Authors

Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
Wanda K. O'Neal
Wanda K. O'Neal University of North Carolina at Chapel Hill
Barry R. Stripp
Barry R. Stripp Cedars-Sinai Medical Center
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Vineet D. Menachery
Vineet D. Menachery The University of Texas Medical Branch at Galveston
Lisa E. Gralinski
Lisa E. Gralinski University of North Carolina at Chapel Hill
Boyd Yount
Boyd Yount University of North Carolina at Chapel Hill
Brigid L.M. Hogan
Brigid L.M. Hogan Duke University
Raymond J. Pickles
Raymond J. Pickles University of North Carolina at Chapel Hill
Matthew D. Wilkerson
Matthew D. Wilkerson Uniformed Services University of the Health Sciences

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