Lisa E. Gralinski

Overview

Best Publications

• Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

  Timothy P. Sheahan;Amy C. Sims;Rachel L. Graham;Vineet D. Menachery

  1740
  Citations

• SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

  Yixuan J. Hou;Kenichi Okuda;Caitlin E. Edwards;David R. Martinez

  1593
  Citations

• Return of the Coronavirus: 2019-nCoV.

  Lisa E. Gralinski;Vineet D. Menachery

  1587
  Citations

• Potently neutralizing and protective human antibodies against SARS-CoV-2.

  Seth J. Zost;Pavlo Gilchuk;James Brett Case;Elad Binshtein

  1155
  Citations

• A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

  Vineet D. Menachery;Boyd L. Yount;Kari Debbink;Sudhakar Agnihothram

  1130
  Citations

• SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

  Yixuan J. Hou;Shiho Chiba;Peter Halfmann;Camille Ehre

  935
  Citations

• Animal models for COVID-19.

  César Muñoz-Fontela;William E. Dowling;Simon G.P. Funnell;Pierre S. Gsell

  822
  Citations

• The genome architecture of the collaborative cross mouse genetic reference population

  Fuad A. Iraqi;Mustafa Mahajne;Yasser Salaymah;Hani Sandovski

  702
  Citations

• A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.

  Kenneth H. Dinnon;Sarah R. Leist;Alexandra Schäfer;Caitlin E. Edwards

  667
  Citations

• A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

  Meagan Bolles;Damon Deming;Kristin Michelle Long;Sudhakar Agnihothram

  635
  Citations

• A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.

  Sarah R. Leist;Kenneth H. Dinnon;Alexandra Schäfer;Longping V. Tse

  626
  Citations

• Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

  Lisa E. Gralinski;Timothy Patrick Sheahan;Thomas E. Morrison;Vineet D. Menachery;Vineet D. Menachery

  609
  Citations

• A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.

  Ahmed O. Hassan;Natasha M. Kafai;Igor P. Dmitriev;Julie M. Fox

  604
  Citations

• Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.

  Alexandra C. Walls;Brooke Fiala;Alexandra Schäfer;Samuel Wrenn

  544
  Citations

• Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.

  Andrea J. Pruijssers;Andrea J. Pruijssers;Amelia S. George;Amelia S. George;Alexandra Schäfer;Sarah R. Leist

  517
  Citations

• SARS-like WIV1-CoV poised for human emergence

  Vineet D. Menachery;Boyd L. Yount;Amy C Sims;Kari Debbink

  485
  Citations

• Genetic analysis of complex traits in the emerging Collaborative Cross

  David L. Aylor;William Valdar;Wendy Foulds-Mathes;Ryan J. Buus

  399
  Citations

• SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.

  Angela Wahl;Lisa E. Gralinski;Claire E. Johnson;Wenbo Yao

  395
  Citations

• Molecular pathology of emerging coronavirus infections

  Lisa E Gralinski;Ralph S Baric

  373
  Citations

• Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.

  C. Garrett Rappazzo;Longping V. Tse;Chengzi I. Kaku;Daniel Wrapp

  337
  Citations