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Genetics

D-Index
65
Citations
18821
World Ranking
2678
National Ranking
1176

Overview

Shannon K. McWeeney is affiliated with Oregon Health & Science University in the United States. Their research spans primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a significant focus on Molecular Biology, Hematology, Immunology, Infectious Diseases, and Genetics as subfields of study.

The main topics of McWeeney's work include:

  • Acute Myeloid Leukemia Research
  • Protein Degradation and Inhibitors
  • Chronic Myeloid Leukemia Treatments
  • Cancer Genomics and Diagnostics
  • Chronic Lymphocytic Leukemia Research
  • Histone Deacetylase Inhibitors Research
  • Immune Cell Function and Interaction

Their recent scientific publications illustrate a strong emphasis on leukemia and immune system function. Selected papers include:

  • "Reporting guidelines for human microbiome research: the STORMS checklist," 2021, Nature Medicine
  • "Integrative analysis of drug response and clinical outcome in acute myeloid leukemia," 2022, Cancer Cell
  • "Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia," 2020, Nature Cancer
  • "The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance," 2021, Cancer Cell
  • "Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia," 2020, Proceedings of the National Academy of Sciences

Frequent collaboration is a notable aspect of McWeeney's scholarly work. The scientist has closely worked with:

  • Daniel Bottomly
  • Jeffrey Tyner
  • Brian Druker
  • Sophia Jeng
  • Stephen E. Kurtz

Their publications appear regularly in journals and platforms including:

  • Blood
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Blood Cancer Discovery

McWeeney's research contributes to advancing understanding in acute myeloid leukemia mechanisms, treatment responses, and the tumor microenvironment. Their work also extends into protein degradation pathways and immune cell interactions related to cancer and other diseases within the scope of molecular biology and hematology.

Best Publications

  • Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.

    Nicole M. Kuderer;Toni K. Choueiri;Dimpy P. Shah;Yu Shyr

  • Functional genomic landscape of acute myeloid leukaemia

    Jeffrey W. Tyner;Cristina E. Tognon;Cristina E. Tognon;Daniel Bottomly;Beth Wilmot

  • Defining the CREB Regulon: A Genome-Wide Analysis of Transcription Factor Regulatory Regions

    Soren Impey;Sean R. McCorkle;Hyunjoo Cha-Molstad;Jami M. Dwyer

  • The BioPAX community standard for pathway data sharing

    Emek Demir;Emek Demir;Michael P. Cary;Suzanne Paley;Ken Fukuda

  • The genome architecture of the collaborative cross mouse genetic reference population

    Fuad A. Iraqi;Mustafa Mahajne;Yasser Salaymah;Hani Sandovski

  • Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML

    Julia E. Maxson;Jason Gotlib;Daniel A. Pollyea;Angela G. Fleischman

  • MIFlowCyt: the minimum information about a Flow Cytometry Experiment.

    Jamie A. Lee;Josef Spidlen;Keith Boyce;Jennifer Cai

  • Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease

    P. Hemachandra Reddy;Shannon McWeeney;Byung S. Park;Maria Manczak

  • Reporting guidelines for human microbiome research: the STORMS checklist

    Chloe Mirzayi;Audrey Renson;Massive Analysis

  • High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy.

    Stephanie G. Willis;Thoralf Lange;Thoralf Lange;Thoralf Lange;Shadmehr Demehri;Shadmehr Demehri;Shadmehr Demehri;Sandra Otto;Sandra Otto;Sandra Otto

  • Controlling for Contaminants in Low-Biomass 16S rRNA Gene Sequencing Experiments.

    Lisa Karstens;Mark Asquith;Sean Davin;Damien Fair

  • Does the Urinary Microbiome Play a Role in Urgency Urinary Incontinence and Its Severity

    Lisa Karstens;Mark Asquith;Sean Davin;Patrick Stauffer

  • The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells

    Tamilla Nechiporuk;Stephen E. Kurtz;Olga Nikolova;Tingting Liu

  • Evaluating Gene Expression in C57BL/6J and DBA/2J Mouse Striatum Using RNA-Seq and Microarrays

    Daniel Bottomly;Nicole A. R. Walter;Nicole A. R. Walter;Jessica Ezzell Hunter;Priscila Darakjian

  • Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

    Lisa E. Gralinski;Armand Bankhead;Sophia Jeng;Vineet D. Menachery

  • A Viral microRNA Down-Regulates Multiple Cell Cycle Genes through mRNA 5′UTRs

    Finn Grey;Rebecca Tirabassi;Heather Meyers;Guanming Wu

  • Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity

    Andrea Sottoriva;Joost J.C. Verhoeff;Tijana Borovski;Shannon K. McWeeney

  • Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

    Martin T. Ferris;David L. Aylor;Daniel Bottomly;Alan C. Whitmore

  • Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia

    Alyssa Carey;David K. Edwards;Christopher A. Eide;Christopher A. Eide;Laura Newell

  • The Plasmodium genome database

    Jessica C. Kissinger;Brian P. Brunk;Jonathan Crabtree;Martin J. Fraunholz

Frequent Co-Authors

Brian J. Druker
Brian J. Druker Oregon Health & Science University
John K. Belknap
John K. Belknap Oregon Health & Science University
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Michael W. Deininger
Michael W. Deininger University of Utah
Vineet D. Menachery
Vineet D. Menachery The University of Texas Medical Branch at Galveston
Lisa E. Gralinski
Lisa E. Gralinski University of North Carolina at Chapel Hill
Fernando Pardo-Manuel de Villena
Fernando Pardo-Manuel de Villena University of North Carolina at Chapel Hill
John C. Crabbe
John C. Crabbe Oregon Health & Science University
Alexandra Schäfer
Alexandra Schäfer Duke University
Katrina M. Waters
Katrina M. Waters Pacific Northwest National Laboratory

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