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Gilles Tamagnan

Gilles Tamagnan

D-Index & Metrics

Neuroscience

D-Index
40
Citations
6181
World Ranking
8107
National Ranking
3478

Overview

Gilles Tamagnan is affiliated with Yale University in the United States and has a research focus spanning medicine, biochemistry, genetics, molecular biology, and neuroscience. Their work integrates several subfields including cellular and molecular neuroscience, neurology, molecular biology, genetics, and radiology, nuclear medicine, and imaging.

The scientist's main topics of study include:

  • Neuroscience and Neuropharmacology Research
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Medical Imaging Techniques and Applications
  • Nuclear Receptors and Signaling
  • Pharmacological Receptor Mechanisms and Effects
  • Cholesterol and Lipid Metabolism

The recent scholarly contributions of Gilles Tamagnan feature research published in respected journals, covering a range of subjects related to neuroinflammation, imaging, and receptor studies. Notable papers include:

  • "Brain microglia activation and peripheral adaptive immunity in Parkinson's disease: a multimodal PET study," 2022, Journal of Neuroinflammation
  • "Rapidly (and Successfully) Translating Novel Brain Radiotracers From Animal Research Into Clinical Use," 2020, Frontiers in Neuroscience
  • "Preclinical characterization of [18F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase," 2021, European Journal of Nuclear Medicine and Molecular Imaging
  • "Diagnostic value of striatal 18F-FP-DTBZ PET in Parkinson's disease," 2022, Frontiers in Aging Neuroscience
  • "Evaluation of (rac)-, (R)-, and (S)-18F-OF-NB1 for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Receptors in Nonhuman Primates," 2022, Journal of Nuclear Medicine

Frequent collaborators in their research include:

  • Olivier Barret
  • Shuying Liu
  • Hongwen Qiao
  • Tatsuki Koike
  • Cristian Constantinescu

Gilles Tamagnan's publications commonly appear in the following venues:

  • Journal of Nuclear Medicine
  • European Journal of Nuclear Medicine and Molecular Imaging
  • Frontiers in Aging Neuroscience
  • Journal of Medicinal Chemistry
  • Journal of Neuroinflammation

Their research contributions primarily address neurological conditions such as Parkinson's disease through advanced imaging techniques, receptor characterization, and neuropharmacology. The integration of nuclear imaging methods like PET in neurological and molecular studies is a significant aspect of their work.

Best Publications

  • Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers

    Julie K. Staley;Suchitra Krishnan-Sarin;Sami Zoghbi;Gilles Tamagnan

  • Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers.

    Julie K. Staley;Suchitra Krishnan-Sarin;Kelly P. Cosgrove;Erica Krantzler

  • 5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors

    Alexey G. Mukhin;Daniela Gündisch;Andrew G. Horti;Andrei O. Koren

  • Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study

    Andre Mueller;Santiago Bullich;Olivier Barret;Jennifer Madonia

  • Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies

    Heiko Kroth;Felix Oden;Jerome Molette;Hanno Schieferstein

  • One-step synthesis of 2-arylbenzothiazole (‘BTA’) and -benzoxazole precursors for in vivo imaging of β-amyloid plaques

    David Alagille;Ronald M. Baldwin;Gilles D. Tamagnan;Gilles D. Tamagnan

  • Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes.

    Tomas de Paulis;Kamondanai Hemstapat;Yelin Chen;Yongqin Zhang

  • A close structural analog of 2-methyl-6-(phenylethynyl)-pyridine acts as a neutral allosteric site ligand on metabotropic glutamate receptor subtype 5 and blocks the effects of multiple allosteric modulators.

    Alice L. Rodriguez;Yi Nong;Nishant K. Sekaran;David Alagille

  • β2-Nicotinic Acetylcholine Receptor Availability During Acute and Prolonged Abstinence From Tobacco Smoking

    Kelly P. Cosgrove;Jeffery Batis;Frederic Bois;Paul K. Maciejewski

  • Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex.

    Lucas Lecourtier;Houman Homayoun;Gilles Tamagnan;Bita Moghaddam

  • Sex differences in diencephalon serotonin transporter availability in major depression.

    Julie K. Staley;Gerard Sanacora;Gilles Tamagnan;Paul K. Maciejewski

  • Persistent β2*-Nicotinic Acetylcholinergic Receptor Dysfunction in Major Depressive Disorder

    Aybala Saricicek;Irina Esterlis;Kathleen H. Maloney;Yann S. Mineur

  • Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys.

    Gunasingh J. Masilamoni;James W. Bogenpohl;David Alagille;Kristen Delevich

  • The Phosphodiesterase 10 Positron Emission Tomography Tracer, [18F]MNI-659, as a Novel Biomarker for Early Huntington Disease

    David S. Russell;Olivier Barret;Danna L. Jennings;Joseph H. Friedman

  • [18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer's disease.

    Sandra Sanabria Bohórquez;Jan Marik;Annie Ogasawara;Jeff N Tinianow

  • N-Substituted Analogs of 2β-Carbomethoxy-3β-(4‘-iodophenyl)tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain

    John L. Neumeyer;Gilles Tamagnan;Shaoyin Wang;Yigong Gao

  • Radiosynthesis of [18F] N-3-fluoropropyl-2-β-carbomethoxy-3-β-(4-iodophenyl) nortropane and the first human study with positron emission tomography

    Thomas Chaly;Vijay Dhawan;Ken Kazumata;Angelo Antonini

  • Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nerves.

    Hajime A. Tokuno;Charles W. Bradberry;Brian Everill;Samuel K. Agulian

  • Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.

    Yaping Chu;Scott Muller;Adriana Tavares;Olivier Barret

  • A Novel Family of Potent Negative Allosteric Modulators of Group II Metabotropic Glutamate Receptors

    Kamondanai Hemstapat;Herve Da Costa;Yi Nong;Ashley E. Brady

  • Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects.

    Masahiro Fujita;John P. Seibyl;Bruce D. Vaupel;Gilles Tamagnan

Frequent Co-Authors

Robert B. Innis
Robert B. Innis National Institutes of Health
Kelly P. Cosgrove
Kelly P. Cosgrove Yale University
Yu-Shin Ding
Yu-Shin Ding New York University
Edythe D. London
Edythe D. London University of California, Los Angeles
Sherry A. McKee
Sherry A. McKee Yale University
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Marina R. Picciotto
Marina R. Picciotto Yale University
Tetsuya Suhara
Tetsuya Suhara National Institutes for Quantum and Radiological Science and Technology
Sami S. Zoghbi
Sami S. Zoghbi National Institutes of Health

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