World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
58
Citations
10712
World Ranking
10745
National Ranking
2957

Research.com Recognitions

  • 2011 - Fellow of the American Chemical Society
  • 1984 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Dopamine
  • Biochemistry

John L. Neumeyer mainly investigates Dopamine, Stereochemistry, Internal medicine, Endocrinology and Receptor. His Dopamine research integrates issues from Monoamine neurotransmitter, Serotonin, Neurotransmitter and Tropane. John L. Neumeyer has included themes like Ligand binding assay, GTPgammaS and Binding site in his Stereochemistry study.

In his study, Washout and Basal ganglia is inextricably linked to Human brain, which falls within the broad field of Internal medicine. The Globus pallidus research John L. Neumeyer does as part of his general Endocrinology study is frequently linked to other disciplines of science, such as Biting, therefore creating a link between diverse domains of science. His Receptor research includes elements of Substituent and Selectivity.

His most cited work include:

  • SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates (335 citations)
  • Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects (264 citations)
  • Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders (260 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Stereochemistry, Dopamine, Pharmacology, Receptor and Dopamine receptor. His research integrates issues of Chemical synthesis and Binding site in his study of Stereochemistry. His Dopamine research is multidisciplinary, incorporating perspectives in Tropane and Serotonin.

His research investigates the connection between Tropane and topics such as Dopamine transporter that intersect with problems in Nuclear medicine. His Pharmacology study combines topics from a wide range of disciplines, such as Spiperone, Dopamine antagonist and Dopamine agonist. His studies in Dopamine receptor integrate themes in fields like Dopaminergic and Nucleus accumbens.

He most often published in these fields:

  • Stereochemistry (44.24%)
  • Dopamine (32.12%)
  • Pharmacology (23.94%)

What were the highlights of his more recent work (between 2003-2021)?

  • Stereochemistry (44.24%)
  • Receptor (25.15%)
  • Agonist (19.09%)

In recent papers he was focusing on the following fields of study:

Stereochemistry, Receptor, Agonist, Pharmacology and Dopamine are his primary areas of study. His biological study spans a wide range of topics, including Opioid receptor, Chemical synthesis and Ligand. The study incorporates disciplines such as Structure–activity relationship, Aporphines and Aporphine in addition to Receptor.

As a part of the same scientific family, he mostly works in the field of Agonist, focusing on Dopamine receptor D2 and, on occasion, Dopaminergic and Radioligand. His Pharmacology study incorporates themes from Dopamine receptor, Inverse agonist and Apomorphine. His Dopamine research is covered under the topics of Endocrinology and Internal medicine.

Between 2003 and 2021, his most popular works were:

  • Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders (260 citations)
  • Advances in development of dopaminergic aporphinoids. (85 citations)
  • A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey (80 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Dopamine
  • Biochemistry

His scientific interests lie mostly in Stereochemistry, Agonist, Receptor, Pharmacology and Opioid. His Stereochemistry research includes themes of Opioid receptor, Chemical synthesis and Ligand. The various areas that John L. Neumeyer examines in his Agonist study include Pharmacophore, Dopamine receptor D2 and Structure–activity relationship.

His work in Receptor is not limited to one particular discipline; it also encompasses Dopamine. He has included themes like Biochemistry, Tropane and Serotonin in his Dopamine study. His studies deal with areas such as Morphine and Antagonist as well as Opioid.

Best Publications

  • SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.

    Marc Laruelle;Ronald M. Baldwin;Robert T. Malison;Yolanda Zea-Ponce

  • Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.

    B K Madras;R D Spealman;M A Fahey;J L Neumeyer

  • Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

    Marc Laruelle;Elizabeth Wallace;John P. Seibyl;Ronald M. Baldwin

  • Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders

    Na Ye;John L. Neumeyer;Ross J. Baldessarini;Xuechu Zhen

  • [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain.

    Neumeyer Jl;Wang Sy;Milius Ra;Baldwin Rm

  • N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters.

    J. L. Neumeyer;S. Wang;Yigong Gao;R. A. Milius

  • In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428.

    Dean F. Wong;Babington Yung;Robert F. Dannals;Elias K. Shaya;Elias K. Shaya

  • Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.

    Tatsuya Ishikawa;Vijay Dhawan;Ken Kazumata;Thomas Chaly

  • Dopamine Transporter Imaging with Fluorine-18-FPCIT and PET

    Ken Kazumata;Vijay Dhawan;Thomas Chaly;Angelo Antonini

  • Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT.

    Robert Innis;Ronald Baldwin;Elzbieta Sybirska;Yolanda Zea

  • Dopamine D2 receptor binding sites for agonists. A tetrahedral model.

    P Seeman;M Watanabe;D Grigoriadis;J L Tedesco

  • SPECT Imaging of Dopamine Transporters in Human Brain with Iodine-123-Fluoroalkyl Analogs of β-CIT

    Anissa Abi-Dargham;Mitchell S. Gandelman;Gabriel A. DeErausquin;Yolanda Zea-Ponce

  • Differences in the nature of the stereotyped behaviour induced by aporphine derivatives in the rat and in their actions in extrapyramidal and mesolimbic brain areas.

    Brenda Costall;Robert J. Naylor;John L. Neumeyer

  • Advances in development of dopaminergic aporphinoids.

    Ao Zhang;Yi Zhang;Alan R Branfman;Ross J Baldessarini

  • Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines.

    John L Neumeyer;Nora S Kula;Jack Bergman;Ross J Baldessarini

  • [11C]β-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations

    Lars Müller;Christer Halldin;Lars Farde;Per Karlsson

  • The Sigma-RBI handbook of receptor classification and signal transduction

    Keith J. Watling;J. W. Kebabian;John L. Neumeyer

  • Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.

    John L. Neumeyer;Ao Zhang;Wennan Xiong;Xiao-Hui Gu

  • N-Substituted Analogs of 2β-Carbomethoxy-3β-(4‘-iodophenyl)tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain

    John L. Neumeyer;Gilles Tamagnan;Shaoyin Wang;Yigong Gao

  • Radiosynthesis of [18F] N-3-fluoropropyl-2-β-carbomethoxy-3-β-(4-iodophenyl) nortropane and the first human study with positron emission tomography

    Thomas Chaly;Vijay Dhawan;Ken Kazumata;Angelo Antonini

  • Recent Progress in Development for Dopamine Receptor Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders

    Ao Zhang;John L. Neumeyer;Ross J. Baldessarini

Frequent Co-Authors

Ross J. Baldessarini
Ross J. Baldessarini Harvard University
Jean M. Bidlack
Jean M. Bidlack University of Rochester
Robert B. Innis
Robert B. Innis National Institutes of Health
Dennis S. Charney
Dennis S. Charney Icahn School of Medicine at Mount Sinai
Philip Seeman
Philip Seeman University of Toronto
Gilles Tamagnan
Gilles Tamagnan Yale University
Hyman B. Niznik
Hyman B. Niznik University of Toronto
Frank I. Tarazi
Frank I. Tarazi Harvard University
Paul Vouros
Paul Vouros Northeastern University
Bertha K. Madras
Bertha K. Madras Harvard University

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